An intervention trial on efficacy of atropine and multi‐focal glasses in controlling myopic progression

Wiley - Tập 79 Số 3 - Trang 233-236 - 2001
Yung‐Feng Shih1, Chuhsing Kate Hsiao2, Chien‐Jen Chen2, Ching‐Wei Chang2, Por T. Hung1, Luke Lin1
1Department of Ophthalmology, National Taiwan University Hospital, Taipei.
2Institute of Epidemiology, National Taiwan University, Taipei, Taiwan

Tóm tắt

ABSTRACT. Purpose: This randomized clinical trial assessed the treatment effects of atropine and/or multi‐focal lenses in decreasing the progression rate of myopia in children.Methods: Two hundred and twenty‐seven schoolchildren with myopia, aged from 6 to 13 years, who were stratified based on gender, age and the initial amount of myopia were randomly assigned to three treatment groups: 0.5% atropine with multi‐focal glasses, multi‐focal glasses, and single vision spectacles. Each subject was followed for at least eighteen months. These results report on the 188 patients available for the follow‐up.Results: The mean progression of myopia in atropine with multi‐focal glasses group (0.41 D) was significantly less than the multi‐focal (1.19 D) and single vision group (1.40 D) (p<0.0001). But no significant difference was noted between the last two groups (p=0.44). The progression of myopia was significantly correlated with the increases of axial length (r=0.65, p=0.0001), but not with the changes of corneal power (r=−0.09), anterior chamber depth (r=−0.023), lens thickness (r=−0.08), or intra‐ocular pressure (r=−0.008).Conclusion: The 0.5% atropine with multi‐focal lenses can slow down the progression rate of myopia. However, multi‐focal lenses alone showed no difference in effect compared to control.

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Tài liệu tham khảo

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Thông tin
Thông tin xuất bản

Wiley

Tập 79 Số 3

233-236

Thông tin tác giả