Acute physiological responses during blood substitution with colloidal gelatin in conscious rats
Tóm tắt
The effects of exchange-transfusion with a proprietary gelatin-based plasma volume expander, Haemaccel, have been investigated in conscious, chronically-catheterized rats. No adverse changes in basic cardiovascular or respiratory functions occurred during the procedure although an increase in intravascular fluid sodium but not potassium concentration was observed.
Tài liệu tham khảo
The Haemaccel used in these studies was kindly donated by Mr N. Cockburn, Hoechst Pharmaceuticals, Hounslow, UK.
Geyer, R.P., Fedn Proc.34 (1975) 1525.
Riess, J.G., and LeBlanc, M., Angew. Chem.17 (1978) 621.
Naito, R., and Yokoyama, K., in: Perfluorochemical blood substitutes, Green Cross Tech. Inform., Ser. No. 5. Green Cross Corp. Osaka 1978.
Fournier, G., Barrois, V., Girard, C., Robert, D., and Foulleteir, L., Experientia36 (1980), 568.
Baldwin, J.E., and Gill, B., Med. Lab. Sci.29 (1982) 45.
Lowe, K.C., Biologist30 (1983) 105.
Lowe, K.C., McNaughton, D.C., and Hardy, R.N., in: Oxygen-carring colloidal blood substitutes, p. 91. Eds R. Frey, H. Beisbarth and K. Stosseck. W. Zuckschwerdt Verlag, Munich 1982.
Snedecor, G.W., and Cochran, W.G., in: Statistical methods, 6th edn. Iowa State College Press, Ames 1967.
Ringler, D.H., and Dabich, L., in: The laboratory rat, vol. 1, p. 105. Eds H.J. Baker, J.R. Lindsey and S.H. Weisbroth. Academic Press, New York 1979.
Walsh, G.M., Ferrone, R.A., Tsuchiyu, M., Woodsand, E.F., and Deland, E.C., Am. J. Physiol.239 (1980) H805.