Acute and subacute effects of nicorandil and isosorbide dinitrate on vessel wall properties of large arteries and hemodynamics in healthy volunteers

M. J. F. Kool1, Janneke J. Spek1, H. A. Struyker Boudier1, A.P.G. Hoeks2, Robert S. Reneman3, R. H. Van Herwaarden4, Luc M. Van Bortel1
1Dept. of Pharmacology, University of Limburg, The Netherlands
2Department of Biophysics, University of Limburg, the Netherlands
3Department of Physiology, Cardiovascular Research Institute Maastricht, University of Limburg, The Netherlands
4E. Merck Nederland, Amsterdam, the Netherlands

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