Accelerated fractionation (AF) compared to conventional fractionation (CF) improves loco-regional control in the radiotherapy of advanced head and neck cancers: results of the EORTC 22851 randomized trial

Ang, 1996, Overall time factor in postoperative radiation: results of a prospective randomised trial, Radiother. Oncol., 40, S30, 10.1016/S0167-8140(96)80117-4

Barendsen, 1982, Dose fractionation, dose rate and isoeffect relationships for normal tissue response, Int. J. Radiat. Oncol. Biol. Phys., 8, 1981, 10.1016/0360-3016(82)90459-X

Begg, 1985, Method to measure the duration of DNA synthesis and the potential doubling time from a single sample, Cytometry, 6, 620, 10.1002/cyto.990060618

Begg, 1990, The predictive value of cell kinetic measurements in a European trial of accelerated fractionation in advanced head and neck tumors: an interim report, Int. J. Radiat. Oncol. Biol. Phys., 19, 1449, 10.1016/0360-3016(90)90357-P

Cox, 1972, Regression models and life-tables, J. R. Statist. Soc., B 34, 187

Cummings, 1996, A prospective randomized trial of hyperfractionated versus conventional once daily radiation for advanced squamous cell carcinomas of the pharynx and larynx, 40, S30

Dische, 1989, Continuous, hyperfractionated, accelerated fractionation (CHART): an interim report upon late morbidity, Radiother. Oncol., 16, 67, 10.1016/0167-8140(89)90071-6

Fowler, 1992, Loss of local control with prolongation in radiotherapy, Int. J. Radiat. Oncol. Biol. Phys., 23, 457, 10.1016/0360-3016(92)90768-D

Fowler, 1990, Further analysis of the time factor in squamous cell carcinoma of the tonsillar region, Radiother. Oncol., 19, 237, 10.1016/0167-8140(90)90150-U

Freedman, 1982, Tables of the number of patients required in clinical trials using the logrank test, Statist. Med., 1, 121, 10.1002/sim.4780010204

Horiot, 1982, Clinical experience with multiple fractions per day (MFD) in the radiotherapy of head and neck carcinoma, J. Eur. Radiother., 3, 79

Horiot, 1985, A phase III study of accelerated fractionation in the radiotherapy of advanced head and neck carcinoma

Horiot, 1988, European Organisation for Research on Treatment of Cancer trials using radiotherapy with multiple fractions per day. A 1978–1987 survey, 149, 10.1159/000415105

Horiot, 1992, Hypeifractionation versus conventional fractionation in oropharyngeal carcinoma: final analysis of a randomized trial of the EORTC cooperative group of radiotherapy, Radiother. Oncol., 25, 231, 10.1016/0167-8140(92)90242-M

Horiot, 1996

Kaplan, 1958, Non parametric estimation from incomplete observations, J. Am. Statist. Assoc., 53, 457, 10.1080/01621459.1958.10501452

Lindstrom, 1991, Re-analysis of the time factor in local control by radiotherapy of T3 T4 squamous cell carcinoma of the larynx, Int. J. Radiat. Oncol. Biol. Phys., 21, 813, 10.1016/0360-3016(91)90702-6

Maciejewski, 1983, The influence of the number of fractions and of overall treatment time on local control and late complication rate in squamous cell carcinoma of the larynx, Int. J. Radiat. Oncol. Biol. Phys., 9, 321, 10.1016/0360-3016(83)90290-0

Mantel, 1966, Evaluation of survival data and two new rank order statistics arising in its consideration, Cancer Chemother. Rep., 50, 163

Overgaard, 1996, Conventional radiotherapy as the primary treatment of squamous cell carcinoma (SCC) of the head and neck. A randomised multicenter study of 5 versus 6 fractions per week. Preliminary report from the Dahanca 6 and 7 trial, Radiother. Oncol., 40, S31, 10.1016/S0167-8140(96)80119-8

Parsons, 1980, A re-evaluation of splitcourse technique for squamous cell carcinoma of the head and neck, Int. J. Radiat. Oncol. Biol. Phys., 6, 1645, 10.1016/0360-3016(80)90246-1

Pavy, 1995, Late effects toxicity scoring: the SOMA scale, Radiother. Oncol., 35, 11, 10.1016/0167-8140(95)97448-M

Pocock, 1975, Sequential treatment assignment with balancing for prognostic factors in the controlled clinical trial, Biometrics, 31, 103, 10.2307/2529712

Saunders, 1996, On behalf of the CHART Steering Committee. Randomised multicentre trials of CHART versus conventional radiotherapy in head and neck and non small cell lung cancer: an interim report, Br. J. Cancer, 73, 1455, 10.1038/bjc.1996.276

Steel, 1993, Tumour growth kinetics, 8

van den Bogaert, 1985, Late results of multiple fractions per day (MFD) with Misonidazole in advanced cancer of the head and neck. A pilot study of the EORTC radiotherapy group, Radiother. Oncol., 3, 139, 10.1016/S0167-8140(85)80018-9

van den Bogaert, 1989, Radiotherapy with multiple fractions per day, 209

van den Bogaert, 1995, The EORTC randomized trial on three fractions per day and Misonidazole (trial n∘ 22811) in advanced head and neck cancers: long-term results and side effects, Radiother. Oncol., 35, 91, 10.1016/0167-8140(95)01538-R

van den Bogaert, 1995, The EORTC randomized trial on three fractions per day and Misonidazole in advanced head and neck cancers: prognostic factors, Radiother. Oncol., 35, 100, 10.1016/0167-8140(95)01539-S

Wang, 1988, Local control of oropharyngeal carcinoma after two accelerated hyperfractionation schemes, Int. J. Radiat. Oncol. Biol. Phys., 14, 1143, 10.1016/0360-3016(88)90390-2

Withers, 1987, Hyperfractionation, 223