Absorption and Disposition of Ginsenosides after Oral Administration of Panax notoginseng Extract to Rats

Drug Metabolism and Disposition - Tập 37 Số 12 - Trang 2290-2298 - 2009
Houfu Liu1, Junling Yang, Feifei Du, Xiumei Gao, Xutao Ma, Yühong Huang, F. Xu, Wei Niu, Fengqing Wang, Yu Mao, Yan Sun, Tong Lu, Changxiao Liu, Boli Zhang, Chuan Li
1Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zhangjiang Hi-tech Park, Shanghai 201203, China

Tóm tắt

Từ khóa


Tài liệu tham khảo

Akao, 1998, Appearance of compound K, a major metabolite of ginsenoside Rb1 by intestinal bacteria, in rat plasma after oral administration—measurement of compound K by enzyme immunoassay, Biol Pharm Bull, 21, 245, 10.1248/bpb.21.245

Chinese Pharmacopoeia Commission, 2005, Pharmacopoeia of the People's Republic of China, vol I, 10

10.1210/jc.2003-031823

10.1111/j.1745-7254.2008.00850.x

10.1023/A:1018943613122

10.1016/j.ejphar.2006.08.001

10.1055/s-2006-957938

10.1111/j.1440-1681.1995.tb02925.x

Lee, 2003, Ginsenoside-Rb1 acts as a weak phytoestrogen in MCF-7 human breast cancer cells, Arch Pharm Res, 26, 58, 10.1007/BF03179933

10.1002/bmc.400

10.1002/bmc.567

10.1002/bmc.813

10.1248/bpb.30.847

10.1016/j.jchromb.2004.05.002

10.1016/S0169-409X(00)00129-0

10.1021/jf026228i

10.1124/dmd.108.021592

10.1001/archinte.158.20.2225

10.1211/jpp.58.8.0001

Odani, 1983, Studies on the absorption, distribution, excretion and metabolism of ginseng saponins. II. The absorption, distribution and excretion of ginsenoside Rg1 in the rat, Chem Pharm Bull, 31, 292, 10.1248/cpb.31.292

Odani, 1983, Studies on the absorption, distribution, excretion and metabolism of ginseng saponins. III. The absorption, distribution and excretion of ginsenoside Rb1 in the rat, Chem Pharm Bull, 31, 1059, 10.1248/cpb.31.1059

10.1016/j.ab.2006.02.025

10.1161/01.CIR.0000140676.88412.CF

10.1023/A:1026451721686

10.1124/dmd.31.8.1065

10.1021/jm020017n

10.1002/rcm.3129

10.1016/S0378-8741(02)00317-3