A randomised multicentre trial of CHART versus conventional radiotherapy in head and neck cancer

Radiotherapy and Oncology - Tập 44 Số 2 - Trang 123-136 - 1997
Stanley Dische1, Michele I. Saunders2, Ann Barrett3, Angela Harvey4, Della Gibson4, Mahesh Parmar4
1Marie Curie Research Wing, Mount Vernon Hospital, Northwood, Middlesex, UK
2Marie Curie Research Wing,#N#Mount Vernon Hospital,#N#Rickmansworth Road,#N#Northwood, Middlesex HA6 2RN, UK
3Beatson Oncology Centre, Western Infirmary, Glasgow, UK
4Medical Research Council Cancer Trials Office, Cambridge UK

Tóm tắt

Từ khóa


Tài liệu tham khảo

Aird, 1995, Quality assurance in the CHART clinical trial, Radiother. Oncol., 36, 235, 10.1016/0167-8140(95)01598-B

Coyle, 1997, Costs of conventional radical radiotherapy versus continuous hyperfractionated accelerated radiotherapy (CHART) in the treatment of patients with head and neck cancer and carcinoma of the bronchus, Clin. Oncol., 10.1016/S0936-6555(05)80065-2

Dische, 1993, Regaud Lecture, Malmö, 1992. The clinical science of radiation oncology, Radiother. Oncol., 28, 93, 10.1016/0167-8140(93)90001-O

Dische, 1989, The recording of morbidity related to radiotherapy, Radiother. Oncol., 16, 103, 10.1016/0167-8140(89)90026-1

Fowler, 1984, Fractionated radiation therapy after Standqvist, Acta Radiol. Oncol., 23, 209, 10.3109/02841868409136014

Hansen, 1997, Importance of overall treatment time for the outcome of radiotherapy of advanced head and neck carcinoma: dependency on tumor differentiation, Radiother. Oncol., 43, 47, 10.1016/S0167-8140(97)01904-X

Horiot, 1997, Accelerated fractionation (AF) compared to conventional fractionation (CF) improves loco-regional control in the radiotherapy of advanced head and neck cancers: results of the EORTC 22851 Randomized Trial, Radiother. Oncol., 10.1016/S0167-8140(97)00079-0

International Commission on Radiation Units and Measurements, 1978, Dose specification for reporting external beam therapy with photons and electrons, Report 29

Leslie, 1991, Parotid gland function following accelerated and conventionally fractionated radiotherapy, Radiother. Oncol., 22, 133, 10.1016/0167-8140(91)90009-6

Million, 1992, The larynx…so to speak: everything I wanted to know about laryngeal cancer I learned in the last 32 years, Int. J. Radiat. Oncol. Biol. Phys., 23, 691, 10.1016/0360-3016(92)90641-T

Overgaard, 1986, Primary radiotherapy of larynx and pharynx carcinoma — an analysis of some factors influencing local control and survival, Int. J. Radiat. Oncol. Biol. Phys., 12, 515, 10.1016/0360-3016(86)90058-1

Overgaard, 1996, Conventional radiotherapy as the primary treatment of squamous cell carcinoma (SCC) of the head and neck. A randomized multicenter study of 5 versus 6 fractions per week — preliminary report from the DAHANCA 6 and 7 trial, Radiother. Oncol., 40, S31, 10.1016/S0167-8140(96)80119-8

Parmar, 1994, The CHART trials: Bayesian design and monitoring in practice, Stat. Med., 13, 1297, 10.1002/sim.4780131304

Saunders, 1996, Accelerated hyperfractionation in non small cell lung cancer, 721

Saunders, 1986, Radiotherapy employing three fractions in each day over a continuous period of 12 days, Br. J. Radiol., 59, 523, 10.1259/0007-1285-59-701-523

Saunders, 1996, Randomised multicentre trials of CHART vs conventional radiotherapy in head and neck and non-small cell lung cancer: an interim report, Br. J. Cancer, 73, 1455, 10.1038/bjc.1996.276

Saunders, 1991, Experience with CHART, Int. J. Radiat. Oncol. Biol. Phys., 21, 871, 10.1016/0360-3016(91)90722-G

Saunders, 1989, Continuous hyperfractionated accelerated radiotherapy in locally advanced carcinoma of the head and neck region, Int. J. Radiat. Oncol. Biol. Phys., 17, 1287, 10.1016/0360-3016(89)90538-5

Trott, 1985, What is known about tumour proliferation rates to choose between accelerated fractionation or hyperfractionation, Radiother. Oncol., 3, 1, 10.1016/S0167-8140(85)80002-5

Wilson, 1995, Studies in bromodeoxyuridine in head and neck cancer and accelerated radiotherapy, Radiother. Oncol., 36, 189, 10.1016/0167-8140(95)01567-Z

Wilson, 1988, Cell proliferation in human tumours measured by in vivo labelling with bromodeoxyuridine, Br. J. Radiol., 61, 419, 10.1259/0007-1285-61-725-419