A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome

Antzelevitch, 1994, Clinical relevance of cardiac arrhythmias generated by afterdepolarizations: role of M cells in the generation of U waves, triggered activity and torsade de pointes, J. Am. Coll. Cardiol., 23, 259, 10.1016/0735-1097(94)90529-0

Bazette, 1920, An analysis of the time-relationships of electrocardiograms, Heart, 7, 353

Benhorin, 1993, Evidence of genetic heterogeneity in the long QT syndrome, Science, 260, 1960, 10.1126/science.8316839

Bonner, 1987, Identification of a family of muscarinic acetylcholine receptor genes, Science, 237, 527, 10.1126/science.3037705

Bruggeman, 1993, ether-a-go-go encodes a voltage-gated channel permeable to K+ and Ca2+ and modulated by cAMP, Nature, 365, 445, 10.1038/365445a0

Covarrubias, 1991, Shaker, shal, shab, and shaw express independent K+ current systems, Neuron, 7, 763, 10.1016/0896-6273(91)90279-9

Curran, 1993, Locus heterogeneity of autosomal dominant long QT syndrome, J. Clin. Invest., 92, 799, 10.1172/JCI116653

Curran, 1993, The elastin gene is disrupted by a translocation associated with supravalvular aortic stenosis, Cell, 73, 159, 10.1016/0092-8674(93)90168-P

Feinberg, 1983, Techniques for radiolabeling DNA to high specific activity, Anal. Biochem., 132, 6, 10.1016/0003-2697(83)90418-9

Green, 1994, Integration of physical, genetic and cytogenetic maps of human chromosome 7: isolation and analysis of yeast artificial chromosomes for 117 mapped genetic markers, Hum. Mol. Genet., 3, 489, 10.1093/hmg/3.3.489

Green, 1995, A human chromosome 7 yeast artificial chromosome (YAC) resource: construction, characterization, and screening, Genomics, 10.1016/0888-7543(95)80123-4

Gyapay, 1994, The 1993–1994 Genethon human genetic linkage map, Nature Genet., 7, 246, 10.1038/ng0694supp-246

Heginbotham, 1994, Mutations in the K+ channel signature sequence, Biophys. J., 66, 1061, 10.1016/S0006-3495(94)80887-2

January, 1989, Early afterdepolarizations: mechanism of induction and block, Circ. Res., 64, 977, 10.1161/01.RES.64.5.977

Jiang, 1994, Two long QT syndrome loci map to chromosomes 3 and 7 with evidence for further heterogeneity, Nature Genet., 8, 141, 10.1038/ng1094-141

Kannel, 1987, Sudden death risk in overt coronary heart diseases: the Framingham study, Am. Heart J., 113, 799, 10.1016/0002-8703(87)90722-8

Keating, 1992, Linkage analysis and long QT syndrome: using genetics to study cardiovascular disease, Circulation, 85, 1973, 10.1161/01.CIR.85.6.1973

Keating, 1991, Linkage of a cardiac arrhythmia, the long QT syndrome, and the Harvey ras-1 gene, Science, 252, 704, 10.1126/science.1673802

Keating, 1991, Consistant linkage of the long QT syndrome to the Harvey ras-1 locus on chromosome 11, Am. J. Hum. Genet., 49, 1335

Koch, 1992, The skeletal muscle chloride channel in dominant and recessive human myotonia, Science, 257, 797, 10.1126/science.1379744

Lathrop, 1985, Multilocus linkage analysis in humans: detection of linkage and estimation of recombination, Am. J. Hum. Genet., 37, 482

Lichter, 1988, Delineation of individual human chromosomes in metaphase and interphase cells by in situ suppression hybridization using recombinant DNA libraries, Hum. Genet., 80, 224, 10.1007/BF01790090

Ludwig, 1994, Functional expression of a rat homologue of the voltage gated ether a go-go potassium channel reveals differences in selectivity and activation kinetics between the Drosophila channel and its mammalian counterpart, EMBO J., 13, 4451, 10.1002/j.1460-2075.1994.tb06767.x

Mackinnon, 1991, Determination of the subunit stoichiometry of a voltage-activated potassium channel, Nature, 350, 232, 10.1038/350232a0

Marchuk, 1990, Construction of T-vectors, a rapid and general system for direct cloning of unmodified PCR products, Nucl. Acids Res., 19, 1154, 10.1093/nar/19.5.1154

Orita, 1989, Detection of polymorphisms of human DNA by gel electrophoresis as single strand conformation polymorphisms, 86, 2766

Ptacek, 1991, Identification of a mutation in the gene causing hyperkalemic periodic paralysis, Cell, 67, 1021, 10.1016/0092-8674(91)90374-8

Romano, 1965, Congenital cardiac arrhythmia, Lancet, 1, 658, 10.1016/S0140-6736(65)91761-7

Roy, 1994, Exclusion of HRAS from long QT locus, Nature Genet., 8, 113, 10.1038/ng1094-113

Schwartz, 1975, The long QT syndrome, Am. Heart J., 109, 378, 10.1016/0002-8703(75)90089-7

Schwartz, 1995, The long QT syndrome, 788

Sternberg, 1990, Bacteriophage P1 cloning system for the isolation, amplification, and recovery of DNA fragments as large as 100 kilobase pairs, 87, 103

Surawicz, 1989, Electrophysiologic substrate of torsade de pointes: dispersion of repolarization or early afterdepolarizations?, J. Am. Coll. Cardiol., 14, 172, 10.1016/0735-1097(89)90069-7

Towbin, 1994, Evidence of genetic heterogeneity in Romano-Ward long QT syndrome (LQTs): analysis of 23 families, Circulation, 90, 2635, 10.1161/01.CIR.90.6.2635

Vincent, 1992, The spectrum of symptoms and QT intervals in carriers of the gene for the long QT syndrome, N. Engl. J. Med., 327, 846, 10.1056/NEJM199209173271204

Ward, 1964, A new familial cardiac syndrome in children, J. Ir. Med. Assoc., 54, 103

Warmke, 1994, A family of potassium channel genes related to eag in Drosophila and mammals, 91, 3438

Willich, 1987, Circadian variation in the incidence of sudden cardiac death in the Framingham heart study population, Am. J. Cardiol., 60, 801, 10.1016/0002-9149(87)91027-7