A brief review of bioluminescent systems (2019)

Current Genetics - Tập 65 - Trang 877-882 - 2019
Aubin Fleiss1,2, Karen S. Sarkisyan1,2,3,4
1Synthetic Biology Group, MRC London Institute of Medical Sciences, London, UK
2Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK
3Planta LLC, Moscow, Russia
4Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, Moscow, Russia

Tóm tắt

Despite being widely used in reporter technologies, bioluminescent systems are largely understudied. Of at least forty different bioluminescent systems thought to exist in nature, molecular components of only seven light-emitting reactions are known, and the full biochemical pathway leading to light emission is only understood for two of them. Here, we provide a succinct overview of currently known bioluminescent systems highlighting available tools for research and discussing future applications.

Tài liệu tham khảo

Deluca M (1976) Firefly luciferase. Adv Enzymol Relat Areas Mol Biol 44:37–68

Fallon TR, Lower SE, Chang CH, Bessho-Uehara M, Martin GJ, Bewick AJ, Behringer M et al (2018) Firefly genomes illuminate parallel origins of bioluminescence in beetles. eLife. https://doi.org/10.7554/eLife.36495

Gupta RK, Patterson SS, Ripp S, Simpson ML, Sayler GS (2003) Expression of the photorhabdus luminescens lux genes (luxA, B, C, D, and E) in Saccharomyces cerevisiae. FEMS Yeast Res 4(3):305–313

Kaskova ZM, Tsarkova AS, Yampolsky IV (2016) 1001 Lights: luciferins, luciferases, their mechanisms of action and applications in chemical analysis, biology and medicine. Chem Soc Rev. https://doi.org/10.1039/c6cs00296j

Kotlobay AA, Sarkisyan KS, Mokrushina YA, Marcet-Houben M, Serebrovskaya EO, Markina NM, Somermeyer LG et al (2018) genetically encodable bioluminescent system from fungi. Proc Natl Acad Sci USA 115(50):12728–12732

Kotlobay AA et al (2019) Natural luciferases: properties and prospects of applications in biomedical research. Acta Nat (under revision)

Krichevsky A, Meyers B, Vainstein A, Maliga P, Citovsky V (2010) Autoluminesc plants. PloS One 5(11):e15461

Landau J, Cameron J, Worthington SS (2009) Avatar (film). 20th Century Fox

Shimomura O, Yampolsky IV (2019) Bioluminescence, chemical principles and methods, 3rd edn. World Scientific Publishing Co Pte Ltd, Hackensack

Verdes A, Gruber DF (2017) Glowing worms: biological, chemical, and functional diversity of bioluminescent annelids. Integr Comp Biol. https://doi.org/10.1093/icb/icx017