A Phase 3 Trial of Bevacizumab in Ovarian Cancer

New England Journal of Medicine - Tập 365 Số 26 - Trang 2484-2496 - 2011
Timothy Perren1, Ann Marie Swart2, Sokbom Kang3, Jonathan A. Ledermann4, Éric Pujade-Lauraine5, Gunnar B. Kristensen6, Mark Sculpher7, Philip Beale8, Andrés Cervantes9, Christian Kurzeder10, Andreas du Bois11, Jalid Sehouli12, Rainer Kimmig13, A. Stähle14, Fiona Collinson1, Sharadah Essapen15, Charlie Gourley16, Alain Lortholary17, Frédèric Selle18, Luís Manso19, Dong Liang20, Marie Plante21, Dan Stark22, Wendi Qian23,2, Mahesh Parmar2, Amit M. Oza24
1St James's Institute of Oncology, St James's University Hospital, Leeds
2Medical Research Council Clinical Trials Unit
3Städtischen Klinikum Solingen, Klinik für Gynäkologie und Geburtshilfe, Solingen
4University College London Biomedical Research Centre, University College London Hospitals
5Université Paris Descartes, Assistance Publique–Hôpitaux de Paris, Hôpitaux Universitaires Paris Centre, Paris
6Department of Gynecologic Oncology and Institute of Medical Informatics, Oslo University Hospital, Oslo
7Department of Obstetrics and Gynecology, University of British Columbia, Vancouver
8Australia New Zealand Gynaecological Oncology Group, Camperdown, NSW, Australia
9Department of Hematology and Medical Oncology, Institute of Health Research Hospital Clinico, University of Valencia, Valencia, Spain
10Universitätsklinikum Ulm, Ulm
11Dr. Horst Schmidt Klinik, Wiesbaden
12Charité Campus Virchow-Klinikum, Berlin
13Universitätsklinikum Essen, Essen
14St. Vincentius Kliniken Karlsruhe
15Foundation Trust, Guildford
16University of Edinburgh Cancer Research Centre, Institute of Genetics and Molecular Medicine, Edinburgh
17Centre Catherine de Sienne, Nantes
18Service d'Oncologie Medicale, Assistance Publique–Hôpitaux de Paris, Hôpital Tenon, Paris
19Department of Oncology, Rigshospitalet, Copenhagen
20Women's Clinic, Helsinki University Central Hospital, Helsinki
21Department of Obstetrics and Gynecology, Laval University, Quebec, QC
22Leeds Institute of Molecular Medicine, Leeds
23Cambridge Cancer Trials Center, Cambridge University Hospitals NHS Foundation Trust, Cambridge
24Princess Margaret Hospital, Toronto

Tóm tắt

Từ khóa


Tài liệu tham khảo

10.1200/JCO.2008.19.1684

10.1200/JCO.2005.03.2938

10.1093/jnci/djj296

10.1093/jnci/djq362

10.1056/NEJMoa052985

10.1056/NEJM199612263352603

Markman M, 2001, J Clin Oncol, 19, 1001, 10.1200/JCO.2001.19.4.1001

10.1016/S0140-6736(09)61157-0

10.1097/00000658-197203000-00014

10.1093/jnci/82.1.4

10.1093/jnci/90.6.447

Huang S, 2000, Cancer Res, 60, 5334

10.1056/NEJMoa032691

Sandler A, Gray R, Brahmer J. Randomised phase II/III trial of paclitaxel (P) plus carboplatin (C) with or without bevacizumab (NSC #704865) in patients with advanced non-squamous non-small cell lung cancer (NSCLC): an Eastern Cooperative Oncology Group (ECOG) trial. Presented at the 41st Annual Meeting of the American Society of Clinical Oncology, Orlando, FL, May 13–17, 2005.

10.1016/j.ejca.2008.07.042

10.1200/JCO.2007.11.5345

10.1200/JCO.2007.12.0782

10.1200/JCO.2007.12.1939

10.1056/NEJMoa1104390

10.1093/jnci/92.3.205

10.1093/jnci/djh081

10.1002/sim.1203