Abou-Samra, 1992, 89, 2732
Allgeier, 1994, The human thyrotropin receptor activates G-proteins Gs and Gq/11, J. Biol. Chem., 269, 13733, 10.1016/S0021-9258(17)36705-4
Arshavsky, 1992, Regulation of deactivation of photoreceptor G protein by its target enzyme and cGMP, Nature, 357, 416, 10.1038/357416a0
Asano, 1984, Activation of the inhibitory GTP-binding protein of adenylate cyclase, Gi, by β-adrenergic receptors in reconstituted phospholipid vesicles, J. Biol. Chem., 259, 9351, 10.1016/S0021-9258(17)42705-0
Ashkenazi, 1987, An M2 muscarinic receptor subtype coupled to both adenylyl cyclase and phosphoinositide turnover, Science, 238, 672, 10.1126/science.2823384
Berstein, 1992, Phospholipase C-β1 is a GTPase-activating protein for Gq/11 its physiologic regulator, Cell, 70, 411, 10.1016/0092-8674(92)90165-9
Beth, 1986, Dynamics and interactions of the anion channel in intact human erythrocytes: an electron paramagnetic resonance spectroscopic study employing a new membrane-impermeant bifunctional spin-label, Biochemistry, 25, 3824, 10.1021/bi00361a013
Bourne, 1993, Molecular machines integrate coincident synaptic signals, Cell, 72, 65, 10.1016/S0092-8674(05)80029-7
Bubis, 1990, Sites of interaction in the complex between β- and γ-subunits of transducin, J. Biol. Chem., 265, 12995, 10.1016/S0021-9258(19)38258-4
Buxton, 1983, Compartments of cyclic AMP and protein kinase in mammalian cardiomyocytes, J. Biol. Chem., 258, 10233, 10.1016/S0021-9258(17)44447-4
Cali, 1992, Selective tissue distribution of G protein y subunits, including a new form of the γ subunits identified by cDNA cloning, J. Biol. Chem., 267, 24023, 10.1016/S0021-9258(18)35939-8
Carlson, 1986, Fractionation of the β subunit common to guanine nucleotidebinding regulatory proteins with the cytoskeleton, Mol. Pharmacol., 30, 463
Carty, 1990, Distinct guanine nucleotide binding and release properties of the three Gi proteins, J. Biol. Chem., 265, 6268, 10.1016/S0021-9258(19)39320-2
Casey, 1994, Lipid modifications of G proteins, Curr. Opin. Cell Biol., 6, 219, 10.1016/0955-0674(94)90139-2
Cerione, 1985, Specificity of the functional interactions of the β-adrenergic receptor and rhodopsin with guanine nucleotide regulatory proteins reconstituted in phospholipid vesicles, J. Biol. Chem., 260, 1493, 10.1016/S0021-9258(18)89619-3
Cerione, 1986, Functional reconstitution of the a2-adrenergic receptor with guanine nucleotide regulatory proteins in phospholipid vesicles, J. Biol. Chem., 261, 3901, 10.1016/S0021-9258(17)35732-0
Cerione, 1987, Functional differences in the βγ complexes of transducin and the inhibitory guanine nucleotide regulatory protein, Biochemistry, 26, 1485, 10.1021/bi00379a041
Chabre, 1994, Coupling of the α2A-adrenergic receptor to multiple G-proteins: a simple approach for estimating receptor-G-protein coupling efficiency in a transient expression system, J. Biol. Chem., 269, 5730, 10.1016/S0021-9258(17)37522-1
Clapham, 1993, New roles for G protein βγ dimers in transmembrane signaling, Nature, 365, 403, 10.1038/365403a0
Coleman, 1994, Structures of active conformations of Giα1 and the mechanism of GTP hydrolysis, Science, 265, 1405, 10.1126/science.8073283
Conklin, 1993, Structural elements of Gα subunits that interactwith Gβγ, receptors, and effectors, Cell, 73, 631, 10.1016/0092-8674(93)90245-L
Conklin, 1993, Substitution of three amino acids switches receptor specificity of Gqα to that of Giα, Nature, 363, 274, 10.1038/363274a0
Crespo, 1994, Rasdependent activation of MAP kinase pathway mediated by G-protein βγ subunits, Nature, 369, 418, 10.1038/369418a0
Daniel-Issakani, 1989, Lipopolysaccharide response is linked to the GTP binding protein, Gi−2, in the promonocytic cell line U937, J. Biol. Chem., 264, 20240, 10.1016/S0021-9258(19)47053-1
Denker, 1992, Mutagenesis of the amino terminus of the a subunit of the G protein, Go: in vitro characterization of αoβγ interactions, J. Biol. Chem., 267, 6272, 10.1016/S0021-9258(18)42691-9
Denker, 1992, Promotion of the GTP-liganded state of the Gαo protein by deletion of the C terminus, J. Biol. Chem., 267, 9998, 10.1016/S0021-9258(19)50190-9
Dohlman, 1991, Model systems for the study of seven-transmembrane-segment receptors, Annu. Rev. Biochem., 60, 653, 10.1146/annurev.bi.60.070191.003253
Dufau, 1978, Actions of choleragen and gonadotropin in isolated Leydig cells: functional compartmentalization of the hormoneactivated cyclic AMP response, J. Biol. Chem., 253, 3721, 10.1016/S0021-9258(17)34861-5
Faure, 1994, cAMP and βγ subunits of heterotrimeric G proteins stimulate the mitogenactivated protein kinase pathway in COS-7 cells, J. Biol. Chem., 269, 7851, 10.1016/S0021-9258(17)37127-2
Federman, 1992, Hormonal stimulation of adenylyl cyclase through Gi-protein βγ subunits, Nature, 356, 159, 10.1038/356159a0
Fung, 1983, Characterization of transducin from bovine retinal rod outer segments. II. Evidence for distinct binding sites and conformational changes revealed by limited proteolysis with trypsin, J. Biol. Chem., 258, 10503, 10.1016/S0021-9258(17)44484-X
Garritsen, 1994, Multiple domains of G protein β confer subunit specificity in βgg interaction, J. Biol. Chem., 269, 24418, 10.1016/S0021-9258(19)51100-0
Gilman, 1987, G proteins: transducers of receptor-generated signals, Annu. Rev. Biochem., 56, 615, 10.1146/annurev.bi.56.070187.003151
Graeser, 1993, Compartmentation of receptors and guanine nucleotide-binding proteins in NG108-15 cells: lack of cross-talk in agonist binding among the α2-adrenergic, muscarinic, and opiate receptors, Mol. Pharmacol., 43, 434
Gudermann, 1992, Evidence for dual coupling of the murine luteinizing hormone receptor to adenylyl cyclase and phosphoinositide breakdown and Ca2+ mobilization: studies with the cloned murine luteinizing hormone receptor expressed in L cells, J. Biol. Chem., 267, 4479, 10.1016/S0021-9258(18)42858-X
Hansen, 1994, Localization of a heterotrimeric G protein γ subunit to focal adhesions and associated stress fibers, J. Cell. Biol., 126, 811, 10.1083/jcb.126.3.811
Hausdorff, 1992, Tyrosine phosphorylation of G protein a subunits by pp60c-src, 89, 5720
Huff, 1985, Physical and immunological characterization of a guanine nucleotide-binding protein purified from bovine cerebral cortex, J. Biol. Chem., 260, 10864, 10.1016/S0021-9258(19)85162-1
Iiri, 1994, Rapid GDP release from Gsα in patients with gain and loss of endocrine function, Nature, 371, 164, 10.1038/371164a0
Jahangeer, 1993, The disaggregation theory of signal transduction revisited: further evidence that G proteins are multimeric and disaggregate to monomers when activated, 90, 8782
Katada, 1987, A novel mechanism for the inhibition of adenylate cyclase via inhibitory GTPbinding proteins: calmodulin-dependent inhibition of the cyclase catalyst by the βγ subunits of GTP-binding proteins, J. Biol. Chem., 262, 11897, 10.1016/S0021-9258(18)45290-8
Katz, 1995, A segment of the C-terminal half of the G-protein subunit specifies its interaction with the γ1 subunit
Kaziro, 1991, Structure and function of signal-transducing GTP-binding proteins, Annu. Rev. Biochem., 60, 349, 10.1146/annurev.bi.60.070191.002025
Keefer, 1994, Unique structural features important for stabilization versus polarization of the α2A-adrenergic receptor on the basolateral membrane of Madin-Darby canine kidney cells, J. Biol. Chem., 269, 16425, 10.1016/S0021-9258(17)34024-3
Kisselev, 1994, A farnesylated domain in the G protein γ subunit is a specific determinant of receptor coupling, J. Biol. Chem., 269, 21399, 10.1016/S0021-9258(17)31815-X
Kleuss, 1991, Assignment of G-protein subtypes to specific receptors inducing inhibition of calcium currents, Nature, 353, 43, 10.1038/353043a0
Kleuss, 1992, Different β-subunits determine G-protein interaction with transmembrane receptors, Nature, 358, 424, 10.1038/358424a0
Kleuss, 1993, Selectivity in signal transduction determined by γ subunits of heterotrimeric G proteins, Science, 259, 832, 10.1126/science.8094261
Koch, 1991, SH2 and SH3 domains: elements that control interactions of cytoplasmic signaling proteins, Science, 252, 668, 10.1126/science.1708916
Lambright, 1994, Structural determinants for activation of the α-subunit of a heterotrimeric G protein, Nature, 369, 621, 10.1038/369621a0
Lechleiter, 1991, Subcellular patterns of calcium release determined by G protein-specific residues of muscarinic receptors, Nature, 350, 505, 10.1038/350505a0
Lee, 1995, Multiple regions of Gα16 contribute to the specificity of activation by the C5a receptor, Mol. Pharmacol.
Lee, 1992, Regulation of retinal cGMP cascade by phosducin in bovine rod photoreceptor cells: interaction of phosducin and transducin, J. Biol. Chem., 267, 25104, 10.1016/S0021-9258(19)74012-5
Linder, 1990, Purification and characterization of Goa. and three types of Giα after expression in Escherichia coli, J. Biol. Chem., 265, 8243, 10.1016/S0021-9258(19)39064-7
Logothetis, 1987, The βγ subunits of GTP-binding proteins activate the muscarinic K+ channel in heart, Nature, 325, 321, 10.1038/325321a0
Lounsbury, 1991, Phosphorylation of Gz in human platelets: selectivity and site of modification, J. Biol. Chem., 266, 22051, 10.1016/S0021-9258(18)54743-8
Lupas, 1992, Do G protein subunits associate via a three-stranded coiled coil?, FEBS Lett., 314, 105, 10.1016/0014-5793(92)80952-D
Maeda, 1994, A twocomponent system that regulates an osmosensing MAP kinase cascade in yeast, Nature, 369, 242, 10.1038/369242a0
Munshi, 1991, A1 adenosine receptors of bovine brain couple to guanine nucleotide-binding proteins Gi1, Gi2, and G0, J. Biol. Chem., 266, 22285, 10.1016/S0021-9258(18)54567-1
Neer, 1994, G proteins: critical control points for transmembrane signals, Protein Sci., 3, 3, 10.1002/pro.5560030102
Neer, 1994, The ancient regulatory-protein family of WD-repeat proteins, Nature, 371, 297, 10.1038/371297a0
Noel, 1993, The 2.2 A crystal structure of transducin-α complexed with GTPγS, Nature, 366, 654, 10.1038/366654a0
Pitcher, 1992, Role of βγ subunits of G proteins in targeting the β-adrenergic receptor kinase to membrane-bound receptors, Science, 257, 1264, 10.1126/science.1325672
Pronin, 1992, Interaction between G-protein β and γ subunit types is selective, 89, 6220
Rahmatullah, 1994, Direct interaction of the α and γ subunits of the G proteins, J. Biol. Chem., 269, 3574, 10.1016/S0021-9258(17)41902-8
Reuveny, 1994, Activation of the cloned muscarinic potassium channel by G protein βγ subunits, Nature, 370, 143, 10.1038/370143a0
Sargiacomo, 1993, Signal transducing molecules and GPI-linked proteins form a caveolin-rich insoluble complex in MDCK cells, J. Cell Biol., 122, 789, 10.1083/jcb.122.4.789
Schlegel, 1979, Activation of adenylate cyclase in hepatic membranes involves interactions of the catalytic unit with multimeric complexes of regulatory proteins, J. Biol. Chem., 254, 5168, 10.1016/S0021-9258(18)50575-5
Schmidt, 1992, Specificity of G protein β and γ subunit interactions, J. Biol. Chem., 267, 13807, 10.1016/S0021-9258(19)49638-5
Senogles, 1990, Specificity of receptor-G protein interactions, J. Biol. Chem., 265, 4507, 10.1016/S0021-9258(19)39592-4
Simon, 1991, Diversity of G proteins in signal transduction, Science, 252, 802, 10.1126/science.1902986
Smrcka, 1993, Regulation of purified subtypes of phosphatidylinositol-specific phospholipase Cβ by G protein α and βγ subunits, J. Biol. Chem., 268, 9667, 10.1016/S0021-9258(18)98401-2
Spring, 1994, A 14-amino acid region of the G protein y subunit is sufficient to confer selectivity of γ binding to the β subunit, J. Biol. Chem., 269, 22882, 10.1016/S0021-9258(17)31727-1
Strittmatter, 1990, Go is a major growth cone protein subject to regulation by GAP-43, Nature, 344, 836, 10.1038/344836a0
Tang, 1991, Type-specific regulation of adenylyl cyclase by G protein βγ subunits, Science, 254, 1500, 10.1126/science.1962211
Thomas, 1993, G protein αo subunit: mutation of conserved cysteines identifies a subunit contact surface and alters GDP affinity, 90, 10295
Thomas, 1993, The G protein βγ subunit: physical and chemical characterization, Biochemistry, 32, 8628, 10.1021/bi00084a034
Touhara, 1994, Binding of G protein βγ-subunits to pleckstrin homology domains, J. Biol. Chem., 269, 10217, 10.1016/S0021-9258(17)34048-6
von Zastrow, 1993, Subtype-specific differences in the intracellular sorting of G proteincoupled receptors, J. Biol. Chem., 268, 763, 10.1016/S0021-9258(18)53997-1
Voyno-Yasenetskaya, 1994, Gα13 stimulates Na-H exchange, J. Biol. Chem., 269, 4721, 10.1016/S0021-9258(17)37604-4
Watson, 1994, A fifth member of the mammalian G-protein β-subunit family, J. Biol. Chem., 269, 22150, 10.1016/S0021-9258(17)31768-4
Wickman, 1994, Recombinant G-protein βγ-subunits activate the muscarinicgated atrial potassium channel, Nature, 368, 255, 10.1038/368255a0
Wieland, 1993, Guanine nucleotide-specific phosphate transfer by guanine nucleotide-binding regulatory protein β-subunits: characterization of the phosphorylated amino acid, J. Biol. Chem., 268, 18111, 10.1016/S0021-9258(17)46818-9
Wilcox, 1994, Analysis of G protein γ subunit heterogeneity using mass spectroscopy, J. Biol. Chem., 269, 12508, 10.1016/S0021-9258(18)99904-7
Wong, 1994, Chimeric muscarinic cholinergic: β-adrenergic receptors that are functionally promiscuous among G proteins, J. Biol. Chem., 269, 18968, 10.1016/S0021-9258(17)32261-5
Xiao, 1994, β2-adrenergic receptorstimulated increase in cAMP in rat heart cells is not coupled to changes in Ca2+ dynamics, contractility, or phospholamban phosphorylation, J. Biol. Chem., 269, 19151, 10.1016/S0021-9258(17)32287-1