Endotoxin and immune activation in chronic heart failure: a prospective cohort study

The Lancet - Tập 353 - Trang 1838-1842 - 1999
Josef Niebauer1,2, Hans-Dieter Volk3, Michael Kemp1, Martin Dominguez4, Ralf R Schumann5, Mathias Rauchhaus1, Philip A Poole-Wilson1, Andrew JS Coats1, Stefan D Anker1,6
1Cardiac Medicine, National Heart and Lung Institute, Imperial College School of Medicine, London, UK
2Kardiologie, Herzzentrum der Universität Leipzig, Germany
3Institut für Medizinische immunologie, Universitätsklinikum Charité, Berlin, Germany
4Heart Science Center, Harefield Hospital, UK
5Institut für Mikrobiologie und Hygiene, Universitätsklinikum Charité, Berlin
6Franz-Volhard-Klinik am Max-Delbrück Centrum für Molekulare Medizin, Charité, Campus Berlin-Buch, Berlin

Tài liệu tham khảo

Levine, 1990, Elevated circulating levels of tumor necrosis factor in severe chronic heart failure, N Engl J Med, 323, 236, 10.1056/NEJM199007263230405 Anker, 1997, Hormonal changes and catabolic/anabolic imbalance in chronic heart failure: the importance of cardiac cachexia, Circulation, 96, 526, 10.1161/01.CIR.96.2.526 Torre-Amione, 1996, Tumor necrosis factor-α and tumor necrosis factor receptors in the failing human heart, Circulation, 93, 704, 10.1161/01.CIR.93.4.704 Anker, 1997, Elevated soluble CD14 receptors and altert cytokines in chronic heart failure, Am J Cardiol, 79, 1426, 10.1016/S0002-9149(97)00159-8 Schumann, 1990, Structure and function of lipopolysaccharide binding protein, Science, 249, 429, 10.1126/science.2402637 Tobias, 1997, Lipopolysaccharide (LPS) binding proteins BPI and LBP from different types of complexes with LPS, J Biol Chem, 272, 18682, 10.1074/jbc.272.30.18682 Lamping, 1998, LPS-binding protein protects mice from septic shock caused by LPS or gram-negative bacteria, J Clin Invest, 101, 2065, 10.1172/JCI2338 Ziegler-Heitbrock, Ulevitch, 1993, CD14: cell surface receptor and differentiation marker, Immunol Today, 14, 121, 10.1016/0167-5699(93)90212-4 Clark, 1996, Exercise limitation in chronic heart failure: central role of the periphery, J Am Coll Cardiol, 28, 1092, 10.1016/S0735-1097(96)00323-3 Sautner, 1998, Early effects of catecholamine therapy on mucosal integrity, intestinal blood flow, and oxygen metabolism in porcine endotoxin shock, Ann Surg, 228, 239, 10.1097/00000658-199808000-00014 Lamping, 1996, Effect of site-directed mutagenisis of gasic residues (Arg 94, Lys 95, Lys 99) of lipopolysaccharide (LPS)-binding protein on binding and transfer of LPS and subsequent immune cell activation, J Immunol, 157, 4648, 10.4049/jimmunol.157.10.4648 Assicot, 1993, High serum procalcitonin concentrations in patients with sepsis and infection, Lancet, 341, 515, 10.1016/0140-6736(93)90277-N Yang, 1998, Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling, Nature, 395, 284, 10.1038/26239 Gomez-Jimenez, 1995, L-arginine: nitric oxide pathway in endotoxemia and human septic shock, Crit Care Med, 23, 253, 10.1097/00003246-199502000-00009 Vanderheyden, 1998, Pro-inflammatory cytokines and endothelium-dependent vasodilation in the forearm: serial assessment in patients with congestive heart failure, Eur Heart J, 19, 747, 10.1053/euhj.1997.0828 Vonhof, 1998, Monocyte activation in congestive heart failure due to coronary artery disease and idiopathic dilated cardiomyopathy, Int J Cardiol, 63, 237, 10.1016/S0167-5273(97)00332-X Wagner, 1998, Adenosine inhibits lipopolysaccharide-induced secretion of tumor necrosis factoralpha in the failing human heart, Circulation, 97, 521, 10.1161/01.CIR.97.6.521 Keel, 1996, Endotoxin tolerance after severe injury and its regulatory mechanisms, J Trauma, 41, 430, 10.1097/00005373-199609000-00008 Randow, 1995, Mechanism of endotoxin desensitization: involvement of interleukin 10 and transforming growth factor beta, J Exp Med, 181, 1887, 10.1084/jem.181.5.1887 Anker, 1997, Tumor necrosis factor and steroid metabolism in chronic heart failure: possible relation to muscle wasting, J Am Coll Cardiol, 30, 997, 10.1016/S0735-1097(97)00262-3 Lew, 1997, Lipopolysaccharide induces cell shrinkage in rabbit ventricular cardiac myocytes, Am J Physiol, 272, H2989 Starr, 1995, Direct action of endotoxin on cardiac muscle, Shock, 3, 380 Munger, 1996, Circulating concentrations of proinflammatory cytokines in mild or moderate heart failure secondary to ischemic or idiopathic dilated cardiomyopathy, Am J Cardiol, 77, 723, 10.1016/S0002-9149(97)89206-5 Keith, 1998, Increased oxidative stress in patients with congestive heart failure, J Am Coll Cardiol, 31, 1352, 10.1016/S0735-1097(98)00101-6 Anker, 1998, Tumor necrosis factor alpha as a predictor of peak leg blood flow in patients with chronic heart failure, Q J Med, 91, 199, 10.1093/qjmed/91.3.199 Yan, 1995, Induction of interleukin-6 (IL-6) by hypoxia in vascular cells, J Biol Chem, 270, 11463, 10.1074/jbc.270.19.11463 Eggesbo, 1994, LPS-induced release of IL-1 beta, IL-6, IL-8, TNF-alpha and sCD14 in whole blood and PBMC from persons with high or low levels of HDL-lipoprotein, Cytokine, 6, 521, 10.1016/1043-4666(94)90080-9