ALDH1 Is a Marker of Normal and Malignant Human Mammary Stem Cells and a Predictor of Poor Clinical Outcome

Cell Stem Cell - Tập 1 - Trang 555-567 - 2007
Christophe Ginestier1, Min Hee Hur2, Emmanuelle Charafe-Jauffret3, Florence Monville3, Julie Dutcher1, Marty Brown1, Jocelyne Jacquemier3, Patrice Viens3, Celina G. Kleer1, Suling Liu1, Anne Schott1, Dan Hayes1, Daniel Birnbaum3, Max S. Wicha1, Gabriela Dontu1
1Department of Internal Medicine, Comprehensive Cancer Center, University of Michigan, Ann Arbor, MI 48109, USA
2Cheil General Hospital, Sungkyunkwan University, Seoul 100-380, South Korea
3Laboratoire d'Oncologie Moléculaire, Centre de Recherche en Cancérologie de Marseille, UMR599 Inserm/Institut Paoli-Calmettes, Marseille 13009, France

Tài liệu tham khảo

Alexe, 2006, Breast cancer prognosis by combinatorial analysis of gene expression data, Breast Cancer Res., 8, R41, 10.1186/bcr1512 Al-Hajj, 2003, Prospective identification of tumorigenic breast cancer cells, Proc. Natl. Acad. Sci. USA, 100, 3983, 10.1073/pnas.0530291100 Armstrong, 2004, Phenotypic characterization of murine primitive hematopoietic progenitor cells isolated on basis of aldehyde dehydrogenase activity, Stem Cells, 22, 1142, 10.1634/stemcells.2004-0170 Boecker, 2002, Usual ductal hyperplasia of the breast is a committed stem (progenitor) cell lesion distinct from atypical ductal hyperplasia and ductal carcinoma in situ, J. Pathol., 198, 458, 10.1002/path.1241 Bonnet, 1997, Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell, Nat. Med., 3, 730, 10.1038/nm0797-730 Bonnet, 1999, CD8(+) minor histocompatibility antigen-specific cytotoxic T lymphocyte clones eliminate human acute myeloid leukemia stem cells, Proc. Natl. Acad. Sci. USA, 96, 8639, 10.1073/pnas.96.15.8639 Chute, 2006, Inhibition of aldehyde dehydrogenase and retinoid signaling induces the expansion of human hematopoietic stem cells, Proc. Natl. Acad. Sci. USA, 31, 11707, 10.1073/pnas.0603806103 Clarke, 2006, Cancer Stem Cells--Perspectives on Current Status and Future Directions: AACR Workshop on Cancer Stem Cells, Cancer Res., 66, 9339, 10.1158/0008-5472.CAN-06-3126 Collins, 2005, Prospective identification of tumorigenic prostate cancer stem cells, Cancer Res., 65, 10946, 10.1158/0008-5472.CAN-05-2018 Dontu, 2003, In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells, Genes Dev., 17, 1253, 10.1101/gad.1061803 Duester, 2000, Families of retinoid dehydrogenases regulating vitamin A function: Production of visual pigment and retinoic acid, Eur. J. Biochem., 267, 4315, 10.1046/j.1432-1327.2000.01497.x Fang, 2005, A tumorigenic subpopulation with stem cell properties in melanomas, Cancer Res., 65, 9328, 10.1158/0008-5472.CAN-05-1343 Ginestier, 2002, Distinct and complementary information provided by use of tissue and DNA microarrays in the study of breast tumor markers, Am. J. Pathol., 161, 1223, 10.1016/S0002-9440(10)64399-4 Gudjonsson, 2002, Isolation, immortalization, and characterization of a human breast epithelial cell line with stem cell properties, Genes Dev., 16, 693, 10.1101/gad.952602 Glinsky, 2005, Microarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer, J. Clin. Invest., 115, 1503, 10.1172/JCI23412 Hess, 2004, Functional characterization of highly purified human hematopoietic repopulating cells isolated according to aldehyde dehydrogenase activity, Blood, 104, 1648, 10.1182/blood-2004-02-0448 Hess, 2006, Selection based on CD133 and high aldehyde dehydrogenase activity isolates long-term reconstituting human hematopoietic stem cells, Blood, 107, 2162, 10.1182/blood-2005-06-2284 Jacquemier, 2005, Protein expression profiling identifies subclasses of breast cancer and predicts prognosis, Cancer Res., 65, 767, 10.1158/0008-5472.767.65.3 Jamieson, 2004, Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML, N. Engl. J. Med., 351, 657, 10.1056/NEJMoa040258 Kelly, 2002, Genetics of myeloid leukemias, Annu. Rev. Genomics Hum. Genet., 3, 179, 10.1146/annurev.genom.3.032802.115046 Kleer, 2003, EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells, Proc. Natl. Acad. Sci. USA, 100, 11606, 10.1073/pnas.1933744100 Krivtsov, 2006, Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9, Nature, 442, 818, 10.1038/nature04980 Kuperwasser, 2004, Reconstruction of functionally normal and malignant human breast tissues in mice, Proc. Natl. Acad. Sci. USA, 101, 4966, 10.1073/pnas.0401064101 Lahad, 2005, Stem cell-ness: A “magic marker” for cancer, J. Clin. Invest., 115, 1463, 10.1172/JCI25455 Li, 2003, Pluripotent stem cells from the adult mouse inner ear, Nat. Med., 9, 1293, 10.1038/nm925 Li, 2007, Identification of pancreatic cancer stem cells, Cancer Res., 67, 1030, 10.1158/0008-5472.CAN-06-2030 Magni, 1996, Induction of cyclophosphamide-resistance by aldehyde-dehydrogenase gene transfer, Blood, 87, 1097, 10.1182/blood.V87.3.1097.bloodjournal8731097 Matsui, 2004, Characterization of clonogenic multiple myeloma cells, Blood, 103, 2332, 10.1182/blood-2003-09-3064 Molofsky, 2004, Diverse mechanisms regulate stem cell self-renewal, Curr. Opin. Cell Biol., 16, 700, 10.1016/j.ceb.2004.09.004 O'Brien, 2006, A human colon cancer cell capable of initiating tumour growth in immunodeficient mice, Nature, 445, 106, 10.1038/nature05372 Orimo, 2005, Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion, Cell, 121, 335, 10.1016/j.cell.2005.02.034 Passegue, 2003, Normal and leukemic hematopoiesis: Are leukemias a stem cell disorder or a reacquisition of stem cell characteristics?, Proc. Natl. Acad. Sci. USA, 100, 11842, 10.1073/pnas.2034201100 Pearce, 2005, Characterization of cells with a high aldehyde dehydrogenase activity from cord blood and acute myeloid leukemia samples, Stem Cells, 23, 752, 10.1634/stemcells.2004-0292 Prince, 2007, Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma, Proc. Natl. Acad. Sci. USA, 104, 973, 10.1073/pnas.0610117104 Reya, 2001, Stem cells, cancer, and cancer stem cells, Nature, 414, 105, 10.1038/35102167 Ricci-Vitiani, 2006, Identification and expansion of human colon-cancer-initiating cells, Nature, 445, 111, 10.1038/nature05384 Sell, 2004, Stem cell origin of cancer and differentiation therapy, Crit. Rev. Oncol. Hematol., 51, 1, 10.1016/j.critrevonc.2004.04.007 Shackleton, 2006, Generation of a functional mammary gland from a single stem cell, Nature, 439, 84, 10.1038/nature04372 Singh, 2004, Identification of human brain tumour initiating cells, Nature, 432, 396, 10.1038/nature03128 Singh, 2004, Cancer stem cells in nervous system tumors, Oncogene, 23, 7267, 10.1038/sj.onc.1207946 Sophos, 2003, Aldehyde dehydrogenase gene superfamily: The 2002 update, Chem. Biol. Interact., 143-144, 5, 10.1016/S0009-2797(02)00163-1 Stingl, 1998, Phenotypic and functional characterization in vitro of a multipotent epithelial cell present in the normal adult human breast, Differentiation, 63, 201, 10.1111/j.1432-0436.1998.00201.x Stingl, 2006, Purification and unique properties of mammary epithelial stem cells, Nature, 439, 993, 10.1038/nature04496 Tlsty, 2001, Stromal cells can contribute oncogenic signals, Semin. Cancer Biol., 11, 97, 10.1006/scbi.2000.0361 van't Veer, 2002, Gene expression profiling predicts clinical outcome of breast cancer, Nature, 415, 530, 10.1038/415530a Villadsen, 2007, Evidence for a stem cell hierarchy in the adult human breast, J. Cell Biol., 177, 87, 10.1083/jcb.200611114 Wicha, 2006, Cancer stem cells: An old idea--a paradigm shift, Cancer Res., 66, 1883, 10.1158/0008-5472.CAN-05-3153 Yoshida, 1998, Human aldehyde dehydrogenase gene family, Eur. J. Biochem., 251, 549, 10.1046/j.1432-1327.1998.2510549.x