Regulating B‐cell activation and survival in response to TLR signals

Immunology and Cell Biology - Tập 85 Số 6 - Trang 471-475 - 2007
Steve Gerondakis1, Raelene J. Grumont1, Ashish Banerjee1
1The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia

Tóm tắt

Following encounters with microbes, cellular activation programs that involve the control of proliferation and survival are initiated in follicular B cells either via the B‐cell receptor in a specific antigen‐defined manner, or through Toll‐like receptors (TLRs) that recognize specific microbial products. This review summarizes and discusses recent findings that shed light on how the nuclear factor κB pathway controls and coordinates B‐cell division and survival following TLR4 engagement.

Từ khóa


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Thông tin xuất bản

Immunology and Cell Biology

Tập 85 Số 6

471-475

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