Optimization of phycocyanin extraction from Spirulina platensis using factorial design

Abalde, 1998, Purification and characterization of phycocyanin from the marine cyanobacterium Synechococcus sp. IO9201, Plant Science, 136, 109, 10.1016/S0168-9452(98)00113-7 Bennett, 1973, Complementary chromatic adaptation in a filamentous blue-green alga, J. Cell Biol., 58, 419, 10.1083/jcb.58.2.419 Bermejo, 2002, Recovery of pure B-phycoerythrin from the microalga Porphyridium cruentum, J. Biotechnol., 93, 73, 10.1016/S0168-1656(01)00385-6 Bermejo, 2003, Preparative purification of B-phycoerythrin from the microalga Porphyridium cruentum by expanded-bed adsorption chromatography, J. Chromatogr. B, 790, 317, 10.1016/S1570-0232(03)00168-5 Box, 1978 Costa, 2000, Modelling of growth conditions for cyanobacterium Spirulina platensis in microcosms, World J. Microbiol. Biotechnol., 16, 15, 10.1023/A:1008992826344 Costa, 2002, Modelling of Spirulina platensis growth in fresh water using response surface methodology, World J. Microbiol. Biotechnol., 18, 603, 10.1023/A:1016822717583 Costa, 2003, Spirulina platensis growth in open raceway ponds using fresh water supplemented with carbon, nitrogen and metal ions, Z. Naturforsch, 58, 76, 10.1515/znc-2003-1-214 Costa, 2004, Improving Spirulina platensis biomass yield using a fed-batch process, Bioresour. Technol., 92, 237, 10.1016/j.biortech.2003.09.013 Haaland, 1989 Kalil, 2000, Response surface analysis and simulation as a tool for bioprocess design and optimization, Proc. Biochem., 35, 539, 10.1016/S0032-9592(99)00101-6 Liu, 2005, One-step chromatography method for efficient separation and purification of R-phycoerythrin from Polysiphonia urceolata, J. Biotechnol., 116, 91, 10.1016/j.jbiotec.2004.09.017 Minkova, 2003, Purification of C-phycocyanin from Spirulina (Arthrospira) fusiformis, J. Biotechnol., 102, 55, 10.1016/S0168-1656(03)00004-X Reddy, 2003, C-Phycocyanin, a selective cyclooxygenase-2 inhibitor, induces apoptosis in lipopolysaccharide-stimulated RAW 264.7 macrophages, Biochem. Biophys. Res. Commun., 304, 385, 10.1016/S0006-291X(03)00586-2 Reis, 1998, Production, extraction and purification of phycobiliproteins from Nostoc sp., Bioresour. Technol., 66, 181, 10.1016/S0960-8524(98)00064-9 Vonshak, 1997 Zarrouk, C., 1966. Contribution à l’étude d’une cyanophycée. Influence de divers facteurs physiques et chimiques sur la croissance et la photosynthèse de Spirulina maxima. Ph.D. Thesis, Paris.