Interleukin-6 is a key mediator of the hepatoprotective and pro-proliferative effects of ischaemic preconditioning in mice

Journal of Hepatology - Tập 45 - Trang 20-27 - 2006
Narci Teoh1, Jacqueline Field1, Geoffrey Farrell1
1Storr Liver Unit, Westmead Millennium Institute, University of Sydney at Westmead Hospital, Westmead, NSW 2145, Australia

Tài liệu tham khảo

Jaeschke, 2003, Molecular mechanisms of hepatic ischemia-reperfusion injury and preconditioning, Am J Physiol Gastrointest Liver Physiol, 284, G15, 10.1152/ajpgi.00342.2002 Teoh, 2003, Hepatic ischaemia reperfusion injury. Pathogenic mechanisms and basis for protection, J Gastroenterol Hepatol, 18, 891, 10.1046/j.1440-1746.2003.03056.x Jaeschke, 1990, Neutrophils contribute to ischemia-reperfusion injury in rat liver in vivo, Fed Am Soc Exp Biol J, 4, 3355 Jaeschke, 1993, Complement activates Kupffer cells and neutrophils during reperfusion after hepatic ischemia, Am J Physiol Gastrointest Liver Physiol, 264, G801, 10.1152/ajpgi.1993.264.4.G801 Colletti, 1990, Role of tumor necrosis factor-α in the pathophysiologic alterations after hepatic ischemia/reperfusion injury in the rat, J Clin Invest, 85, 1936, 10.1172/JCI114656 Rudiger, 2002, Tumor necrosis factor α, but not Fas, mediates hepatocellular apoptosis in the murine ischemic liver, Gastroenterology, 122, 202, 10.1053/gast.2002.30304 Teoh, 2003, Low dose TNF-α protects against hepatic ischemia-reperfusion injury in mice: implications for preconditioning, Hepatology, 37, 118, 10.1053/jhep.2003.50009 Teoh, 2004, Dual role of tumor necrosis factor-α in hepatic ischemia reperfusion injury: studies in tumor necrosis factor-α gene knockout mice, Hepatology, 39, 412, 10.1002/hep.20035 Peralta, 1999, Protective effect of liver preconditioning on liver and lung injury induced by hepatic ischemia-reperfusion in the rat, Hepatology, 30, 1481, 10.1002/hep.510300622 Clavien, 2000, Protective effects of ischemic preconditioning for liver resection performed under inflow occlusion in humans, Ann Surg, 232, 163, 10.1097/00000658-200008000-00001 Teoh, 2002, Hepatic ischemic preconditioning in mice is associated with activation of NF-κB, p38 kinase and cell cycle entry, Hepatology, 36, 94, 10.1053/jhep.2002.33134 Clavien, 2003, A prospective randomized study in 100 consecutive patients undergoing major liver resection with versus without ischemic preconditioning, Ann Surg, 238, 843, 10.1097/01.sla.0000098620.27623.7d Brenner, 1998, Signal transduction during liver regeneration, J Gastroenterol Hepatol, 13, S93, 10.1111/jgh.1998.13.s1.93 Fausto, 2000, Liver regeneration, J Hepatol, 32, 19, 10.1016/S0168-8278(00)80412-2 Yamada, 1997, Initiation of liver growth by tumor necrosis factor: deficient liver regeneration in mice lacking type 1 tumor necrosis factor receptor, Proc Natl Acad Sci USA, 94, 1441, 10.1073/pnas.94.4.1441 Webber, 1998, Tumor necrosis factor primes hepatocytes for DNA replication in the rat, Hepatology, 28, 1226, 10.1002/hep.510280509 Xu, 1998, Glutathione modulates rat and mouse hepatocyte sensitivity to tumour necrosis factor α toxicity, Gastroenterology, 115, 1229, 10.1016/S0016-5085(98)70095-2 Cressman, 1994, Rapid activation of post-hepatectomy factor/nuclear factor kappa B in hepatocytes, a primary response in the regenerating liver, J Biol Chem, 269, 30429, 10.1016/S0021-9258(18)43831-8 Fitzgerald, 1995, Rapid DNA binding by nuclear factor kappa B in hepatocytes at the start of liver regeneration, Cell Growth Differ, 6, 417 Cressman, 1996, Liver failure and defective hepatocyte regeneration in interleukin-6-deficient mice, Science, 274, 1379, 10.1126/science.274.5291.1379 Yamada, 1998, Analysis of liver regeneration in mice lacking type 1 or type 2 tumor necrosis factor receptor: requirement for type 1 but not type 2 receptor, Hepatology, 28, 959, 10.1002/hep.510280410 Selzner, 2002, Cold ischemia decreases liver regeneration after partial liver transplantation in the rat: a TNF-alpha/IL-6 -dependent mechanism, Hepatology, 36, 812, 10.1053/jhep.2002.35535 Camargo, 1997, Interleukin-6 protects liver against warm ischemia/reperfusion injury and promotes hepatocyte proliferation in the rodent, Hepatology, 26, 1513, 10.1002/hep.510260619 Selzner, 1999, Ischemia impairs liver regeneration after major tissue loss in rodents: protective effects of interleukin-6, Hepatology, 30, 469, 10.1002/hep.510300215 Sun, 2003, In vitro interleukin-6 prevents mortality associated with fatty liver transplants in rats, Gastroenterology, 125, 202, 10.1016/S0016-5085(03)00696-6 Hong, 2004, Interleukin-6 alleviates hepatic steatosis and ischemia/reperfusion injury in mice with fatty liver disease, Hepatology, 40, 933, 10.1002/hep.20400 Essani, 1996, Endotoxin-induced activation of nuclear factor transcription factor-κB and expression of E-selectin messenger RNA in hepatocytes, kupffer cells, and endothelial cells in vivo, J Immunology, 156, 2956, 10.4049/jimmunol.156.8.2956 Blindenbacher, 2003, Interleukin-6 is important for survival after partial hepatectomy in mice, Hepatology, 38, 674, 10.1053/jhep.2003.50378 Wuestefeld, 2003, Interleukin-6/glycoprotein 130-dependent pathways are protective during liver regeneration, J Biol Chem, 278, 11281, 10.1074/jbc.M208470200 Guidi, 2003, Interleukin-6 release in the hepatic blood outflow during normothermic liver ischaemia in humans, Dig Liver Dis, 35, 409, 10.1016/S1590-8658(03)00156-7 Cressman, 1995, Rapid activation of the STAT3 transcription factor complex in liver regeneration, Hepatology, 21, 1443, 10.1002/hep.1840210531 Serafin, 2004, Ischemic preconditioning affects interleukin release in fatty livers of rats undergoing ischemia/reperfusion, Hepatology, 39, 688, 10.1002/hep.20089 Taub, 2003, Hepatoprotection via the IL-6/STAT3 pathway, J Clin Invest, 112, 978, 10.1172/JCI19974 Hirano, 2000, Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors, Oncogene, 19, 2548, 10.1038/sj.onc.1203551 Vajdova, 2004, Ischemic preconditioning and intermittent clamping improve murine hepatic microcirculation and kupffer cell function after ischemic injury, Liver Transpl, 10, 520, 10.1002/lt.20126 Debonera, 2001, Activation of interleukin-6/STAT3 and liver regeneration following transplantation, J Surg Res, 96, 289, 10.1006/jsre.2001.6086 Leclercq, 2003, Leptin-specific mechanisms for impaired liver regeneration in ob/ob mice after toxic injury, Gastroenterology, 124, 1451, 10.1016/S0016-5085(03)00270-1 Wustefeld, 2000, Hyperstimulation with interleukin-6 inhibits cell cycle progression after hepatectomy in mice, Hepatology, 32, 514, 10.1053/jhep.2000.16604 Veldhuis, 1996, Potential use of recombinant human interleukin-6 in clinical oncology, Leuk Lymphoma, 20, 673, 10.3109/10428199609052418 Tate, 2001, Phase I trial of simultaneous administration of GM-CSF and IL-6 in patients with renal cell carcinoma: clinical and laboratory effects, Ann Oncol, 12, 655, 10.1023/A:1011123432765