Blood proteins from transgenic animal bioreactors

Transfusion Medicine Reviews - Tập 10 - Trang 131-143 - 1996
Henryk Luboń1,2, Rekha K. Paleyanda1,2, William H. Velander1,2, William N. Drohan1,2
1Jerome H. Holland Laboratory, Plasma Derivatives Department, American Red Cross, Rockville, MD
2Virginia Polytechnic and State University, Blacksburg, VA. USA

Tài liệu tham khảo

Hanahan, 1989, Transgenic mice as probes into complex systems, Science, 246, 1265, 10.1126/science.2686032

Pursel, 1989, Genetic engineering of livestock, Science, 244, 1281, 10.1126/science.2499927

Jänne, 1992, Transgenic animals as bioproducers of therapeutic proteins, Ann Med, 24, 273, 10.3109/07853899209149954

Lee, 1994, Production of biomedical proteins in the milk of transgenic dairy cows: The state of the art, J Contr Rel, 29, 213, 10.1016/0168-3659(94)90068-X

Clark, 1989, Expression of human anti-hemophilic factor IX in the milk of transgenic sheep, Bio/Technol, 7, 487, 10.1038/nbt0589-487

Clark, 1992, Rescuing transgene expression by co-integration, Bio/Technol, 10, 1450, 10.1038/nbt1192-1450

Velander, 1992, Production of biologically active protein C in the milk of transgenic mice, Ann NY Acad Sci, 665, 391, 10.1111/j.1749-6632.1992.tb42602.x

Shani, 1992, Expression of human serum albumin in the milk of transgenic mice, Transgenic Res, 1, 195, 10.1007/BF02524750

Wright, 1991, High level expression of active human alpha-1-antitrypsin in the milk of transgenic sheep, Bio/Technol, 9, 830, 10.1038/nbt0991-830

Swanson, 1992, Production of functional human hemoglobin in transgenic swine, Bio/Technol, 10, 557, 10.1038/nbt0592-557

Sifers, 1987, Tissue specific expression of the human alpha-1-antitrypsin gene in transgenic mice, Nucl Acids Res, 15, 1459, 10.1093/nar/15.4.1459

Kelsey, 1987, Species- and tissue-specific expression of human α1-antitrypsin in transgenic mice, Genes Dev, 1, 161, 10.1101/gad.1.2.161

Rüther, 1987, The human alpha-1-antitrypsin gene is efficiently expressed from two tissue-specific promoters in transgenic mice, Nucl Acids Res, 15, 7519, 10.1093/nar/15.18.7519

Massoud, 1991, Expression of active recombinant human α1-antitrypsin in transgenic animals, J Biotechnol, 18, 193, 10.1016/0168-1656(91)90247-S

Walsh, 1989, High levels of human Apolipoprotein A-I in transgenic mice result in increased plasma levels of small high density lipoprotein (HDL) particles comparable to human HDL3, J Biol Chem, 264, 6488, 10.1016/S0021-9258(18)83374-9

Linton, 1993, Transgenic mice expressing high plasma concentrations of human apolipoprotein B100 and Lipoprotein (a), J Clin Invest, 92, 3029, 10.1172/JCI116927

Jallat, 1990, Characterization of recombinant human factor IX expressed in transgenic mice and in derived trans-immortalized hepatic cell lines, EMBO J, 9, 3295, 10.1002/j.1460-2075.1990.tb07529.x

Iwanaga, 1989, Liver-specific and high-level expression of human serum amyloid P component gene in transgenic mice, Dev Genet, 10, 365, 10.1002/dvg.1020100504

Behringer, 1989, Synthesis of functional human hemoglobin in transgenic mice, Science, 245, 971, 10.1126/science.2772649

Hanscombe, 1989, High-level erythroid-specific expression of the human α-globin gene in transgenic mice and the production of human hemoglobin in murine erythrocytes, Genes Dev, 3, 1572, 10.1101/gad.3.10.1572

O'Donnell, 1994, Influence of the chemical nature of side chain at β108 of Hemoglobin A on the modulation of the oxygen affinity by chloride ions, J Biol Chem, 269, 27692, 10.1016/S0021-9258(18)47041-X

Sharma, 1994, An isologous promoter permits high level expression of human hemoglobin in transgenic swine, Bio/Technol, 12, 55, 10.1038/nbt0194-55

Hochi, 1992, Secretion of bovine α-lactalbumin into the milk of transgenic rats, Mol Reprod Dev, 33, 160, 10.1002/mrd.1080330207

Paleyanda, 1994, Regulation of human Protein C gene expression by the mouse WAP promoter, Transgenic Res, 3, 335, 10.1007/BF01976765

Günzburg, 1991, A mammary-specific promoter directs expression of growth hormone not only to the mammary gland, but also to Bergman glia cells in transgenic mice, Mol Endocrinol, 5, 123, 10.1210/mend-5-1-123

Barash, 1994, Ectopic expression of β-lactoglobulin/human serum albumin fusion genes in transgenic mice: Hormonal regulation and in situ localization, Transgenic Res, 3, 141, 10.1007/BF01973981

Greenberg, 1991, A heterologous hormone response element enhances expression of rat β-casein promoter-driven chloramphenicol acetyltransferase fusion genes in themammary gland of transgenic mice, Mol Endocrinol, 5, 1504, 10.1210/mend-5-10-1504

Carver, 1993, Transgenic livestock as bioreactors: Stable expression of human alpha-1-antitrypsin by a flock of sheep, Bio/Technol, 11, 1263, 10.1038/nbt1193-1263

Ebert, 1991, Transgenic production of a variant of human tissue-type plasminogen activator in the milk: Generation of transgenic goats and analysis of expression, Bio/Technol, 9, 835, 10.1038/nbt0991-835

Ebert, 1994, Induction of human tissue plasminogen activator in the mammary gland of transgenic goats, Bio/Technol, 12, 699, 10.1038/nbt0794-699

Bischoff, 1992, A 17.6 kbp region located upstream of the rabbit WAP gene directs high level expression of a functional human protein variant in transgenic mouse milk, FEBS Lett, 305, 265, 10.1016/0014-5793(92)80683-8

Reddy, 1991, Expression of human growth hormone in the milk of transgenic mice, Anim Biotech, 2, 15, 10.1080/10495399109525745

Carver, 1992, Expression of human α1-antitrypsin in transgenic sheep, Cytotechnology, 9, 77, 10.1007/BF02521734

Rao, 1994, Recombinant hemoglobin A produced in transgenic swine: Structural equivalence with human hemoglobin A, Art Cells, Blood Subs, Immob Biotech, 22, 695, 10.3109/10731199409117900

Drohan, 1994, Inefficient processing of human protein C in the mouse mammary gland, Transgenic Res, 3, 355, 10.1007/BF01976767

Drohan, 1994, Production and purification of recombinant human protein C from the milk of transgenic swine, 501

Gordon, 1987, Production of human tissue plasminogen activator in transgenic mouse milk, Bio/Technol, 5, 1183, 10.1038/nbt1187-1183

Denman, 1991, Transgenic expression of a variant of human tissue-type plasminogen activator in goat milk: Purification and characterization of the recombinant enzyme, Bio/Technol, 9, 839, 10.1038/nbt0991-839

Choo, 1987, Expression of active human clotting factor IX in transgenic mice: Use of cDNA with complete mRNA sequence, Nucl Acids Res, 15, 871, 10.1093/nar/15.3.871

pavirani, 1989, Recombinant proteins of therapeutic interest expressed by lymphoid cell lines derived from transgenic mice, Bio/Technol, 7, 1049, 10.1038/nbt1089-1049

Lee, 1995, Proteolytic processing of human protein C in swine mmmary gland, J Biochem, 118, 81, 10.1093/oxfordjournals.jbchem.a124895

Jenkins, 1994, Glycosylation of recombinant proteins: Problems and prospects, Enzyme Microb Technol, 16, 354, 10.1016/0141-0229(94)90149-X

Goochee, 1991, The oligosaccharides of glycoproteins: Bioprocess factors affecting oligosaccharide structure and their effect on glycoprotein properties, Bio/Technol, 9, 1347, 10.1038/nbt1291-1347

James, 1995, N-glycosylation of recombinant human interferon-γ produced in different animal expression systems, Bio/Technol, 13, 592, 10.1038/nbt0695-592

Harris, 1993, O-linked fucose and other post-translational modifications unique to EGF modules, Glycobiology, 3, 219, 10.1093/glycob/3.3.219

Paleyanda, 1995, γ-Carboxylation of human vitamin K-dependent proteins in the mouse mammary gland, 6, 108

Taylor, 1992, A transgenic mouse that expresses a diversity of human sequence heavy and light chain immunoglobulins, Nucl Acids Res, 20, 6287, 10.1093/nar/20.23.6287

Lonberg, 1994, Antigenspecific human antibodies from mice comprising four distinct genetic modifications, Nature, 368, 856, 10.1038/368856a0

Klobasa, 1987, Composition of sow milk during lactation, J Anim Sci, 64, 1458, 10.2527/jas1987.6451458x

Klobasa, 1989, Variations in the concentrations of immunoglobulins IgG1, IgG2, IgM and IgA in sheep: 1. Changes in the blood serum and in the milk of sheep ofdifferent breeds and cross-breeds during lactation (German), Berl Munch Tierartztl Wochenschr, 102, 123

Sanchez, 1988, Concentration of lactoferrin and transferrin throughout lactation in cow's colostrum and milk, Biol Chem Hoppe-Seyler, 369, 1005, 10.1515/bchm3.1988.369.2.1005

Thompson, 1993, Genetically modified animals: Ethical issues, J Anim Sci, 71, 51, 10.2527/1993.71suppl_351x

Bruggemann, 1993, Environmental safety issues for genetically modified animals, J Anim Sci, 71, 47, 10.2527/1993.71suppl_347x

Dente, 1988, Expression of human α1-acid glycoprotein genes in cultured cells and in transgenic mice, Genes Dev, 2, 259, 10.1101/gad.2.2.259

Ciliberto, 1987, Inducible and tissue-specific expression of human C-reactive protein in transgenic mice, EMBO J, 6, 4017, 10.1002/j.1460-2075.1987.tb02745.x

Mikkelsen, 1992, Tissue-specific expression in the salivary glands of transgenic mice, Nucl Acids Res, 20, 2249, 10.1093/nar/20.9.2249

Lo, 1991, Expression of mouse IgA by transgenic mice, pigs and sheep, Eur J Immunol, 21, 1001, 10.1002/eji.1830210421

Yamamura, 1987, Tissucspecific and developmental expression of human transthyretin gene in transgenic mice, Dev Genet, 8, 195, 10.1002/dvg.1020080404

Colman, 1995, The transgenic mammary gland as a bioreactor: Expectations and realisations, 6, 107

DiTullio, 1992, Production of cystic fibrosis transmembrane conductance regulator in the milk of transgenic mice, Bio/Technol, 10, 74, 10.1038/nbt0192-74

Devinoy, 1994, High level production of human growth hormone in the milk of transgenic mice: The upstream region of the rabbit whey acidic protein (WAP) gene targets transgene expression to the mammary gland, Transgenic Res, 3, 79, 10.1007/BF01974085

Ninomiya, 1994, Functions of milk protein gene 5′ flanking regions on human growth hormone gene, Mol Reprod Dev, 37, 276, 10.1002/mrd.1080370306

Bühler, 1990, Rabbit β-casein promoter directs secretion of human interleukin-2 into the milk of transgenic rabbits, Bio/Technol, 8, 140, 10.1038/nbt0290-140

Krimpenfort, 1991, Generation of transgenic dairy cattle using in vitro embryo production, Bio/Technol, 9, 844, 10.1038/nbt0991-844

Riego, 1993, Production of transgenic mice and rabbits that carry and express the human tissue plasminogen activator cDNA under the control of a bovine αS1 casein promoter, Theriogenology, 39, 1173, 10.1016/0093-691X(93)90015-W

Meade, 1990, Bovine alpha1-casein gene sequences direct high level expression of active human urokinase in mouse milk, Bio/Technol, 8, 443, 10.1038/nbt0590-443