Rothenberg, 2006, The eosinophil., Annu Rev Immunol, 24, 147, 10.1146/annurev.immunol.24.021605.090720
Garofalo, 1992, Eosinophil degranulation in the respiratory tract during naturally acquired respiratory syncytial virus infection., J Pediatr, 120, 28, 10.1016/S0022-3476(05)80592-X
Everard, 1994, Analysis of cells obtained by bronchial lavage of infants with respiratory syncytial virus infection., Arch Dis Child, 71, 428, 10.1136/adc.71.5.428
Harrison, 1999, Respiratory syncytical virus-induced chemokine expression in the lower airways: eosinophil recruitment and degranulation., Am J Respir Crit Care. Med, 159, 1918, 10.1164/ajrccm.159.6.9805083
Matthews, 2005, Role of CCL11 in eosinophilic lung disease during respiratory syncytial virus infection., J Virol, 79, 2050, 10.1128/JVI.79.4.2050-2057.2005
Johnson, 2003, IL-13 is sufficient for respiratory syncytial virus G glycoprotein-induced eosinophilia after respiratory syncytial virus challenge., J Immunol, 170, 2037, 10.4049/jimmunol.170.4.2037
Singh, 2006, Bronchiolitis to asthma: a review and call for studies of gene-viral interactions in asthma causation., Am J Respir Crit Care Med, 19, 19
Everard, 2006, The role of the respiratory syncytial virus in airway syndromes in childhood., Curr Allergy Asthma Rep, 6, 97, 10.1007/s11882-006-0046-z
Busse, 1997, Viruses in asthma., J Allergy Clin Immunol, 100, 147, 10.1016/S0091-6749(97)70216-1
Nagase, 2003, Expression and function of Toll-like receptors in eosinophils: activation by Toll-like receptor 7 ligand., J Immunol, 171, 3977, 10.4049/jimmunol.171.8.3977
Alexopoulou, 2001, Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3., Nature, 413, 732, 10.1038/35099560
Diebold, 2004, Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA., Science, 303, 1529, 10.1126/science.1093616
Heil, 2004, Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8., Science, 303, 1526, 10.1126/science.1093620
Lund, 2004, Recognition of single-stranded RNA viruses by Toll-like receptor 7., Proc Natl Acad Sci U S A, 101, 5598, 10.1073/pnas.0400937101
Lund, 2003, Toll-like receptor 9-mediated recognition of Herpes simplex virus-2 by plasmacytoid dendritic cells., J Exp Med, 198, 513, 10.1084/jem.20030162
O'Neill, 2003, The Toll-IL-1 receptor adaptor family grows to five members., Trends Immunol, 24, 286, 10.1016/S1471-4906(03)00115-7
Domachowske, 1998, Recombinant human eosinophil-derived neurotoxin/RNase 2 functions as an effective antiviral agent against respiratory syncytial virus., J Infect Dis, 177, 1458, 10.1086/515322
Adamko, 1999, Ovalbumin sensitization changes the inflammatory response to subsequent parainfluenza infection. Eosinophils mediate airway hyperresponsiveness, m(2) muscarinic receptor dysfunction, and antiviral effects., J Exp Med, 190, 1465, 10.1084/jem.190.10.1465
Rosenberg, 2001, Eosinophils, eosinophil ribonucleases, and their role in host defense against respiratory virus pathogens., J Leukoc Biol, 70, 691, 10.1189/jlb.70.5.691
Dent, 1990, Eosinophilia in transgenic mice expressing interleukin 5., J Exp Med, 172, 1425, 10.1084/jem.172.5.1425
Haynes, 2001, Involvement of toll-like receptor 4 in innate immunity to respiratory syncytial virus., J Virol, 75, 10730, 10.1128/JVI.75.22.10730-10737.2001
Rees, 1990, Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo., Br J Pharmacol, 101, 746, 10.1111/j.1476-5381.1990.tb14151.x
Forbes, 2004, Immunopathogenesis of experimental ulcerative colitis is mediated by eosinophil peroxidase., J Immunol, 172, 5664, 10.4049/jimmunol.172.9.5664
Foster, 2000, Dissociation of inflammatory and epithelial responses in a murine model of chronic asthma., Lab Invest, 80, 655, 10.1038/labinvest.3780068
Yang, 2003, Eotaxin-2 and IL-5 cooperate in the lung to regulate IL-13 production and airway eosinophilia and hyperreactivity., J Allergy Clin Immunol, 112, 935, 10.1016/j.jaci.2003.08.010
MacKenzie, 2001, Eosinophils promote allergic disease of the lung by regulating CD4(+) Th2 lymphocyte function., J Immunol, 167, 3146, 10.4049/jimmunol.167.6.3146
Shi, 2000, Lymph node trafficking and antigen presentation by endobronchial eosinophils., J Clin Invest, 105, 945, 10.1172/JCI8945
Yu, 2002, Targeted deletion of a high-affinity GATA-binding site in the GATA-1 promoter leads to selective loss of the eosinophil lineage in vivo., J Exp Med, 195, 1387, 10.1084/jem.20020656
Humbles, 2004, A critical role for eosinophils in allergic airways remodeling., Science, 305, 1776, 10.1126/science.1100283
Adamko, 2004, The induction of eosinophil peroxidase release: improved methods of measurement and stimulation., J Immunol Methods, 291, 101, 10.1016/j.jim.2004.05.003
Holt, 1978, Inhibitory activity of unstimulated alveolar macrophages on T-lymphocyte blastogenic response., Am Rev Respir Dis, 118, 791, 10.1164/arrd.1978.118.4.791
Schwarze, 1997, Respiratory syncytial virus infection results in airway hyperresponsiveness and enhanced airway sensitization to allergen., J Clin Invest, 100, 226, 10.1172/JCI119516
Park, 2003, Respiratory syncytial virus-induced airway hyperresponsiveness is independent of IL-13 compared with that induced by allergen., J Allergy Clin Immunol, 112, 1078, 10.1016/j.jaci.2003.08.046
Schoenemeyer, 2005, The interferon regulatory factor, IRF5, is a central mediator of toll-like receptor 7 signaling., J Biol Chem, 280, 17005, 10.1074/jbc.M412584200
Saetta, 1994, Airway eosinophilia in chronic bronchitis during exacerbations., Am J Respir Crit Care Med, 150, 1646, 10.1164/ajrccm.150.6.7952628
Zhu, 2001, Exacerbations of Bronchitis: bronchial eosinophilia and gene expression for interleukin-4, interleukin-5, and eosinophil chemoattractants., Am J Respir Crit Care Med, 164, 109, 10.1164/ajrccm.164.1.2007050
Olszewska-Pazdrak, 1998, Cell-specific expression of RANTES, MCP-1, and MIP-1alpha by lower airway epithelial cells and eosinophils infected with respiratory syncytial virus., J Virol, 72, 4756, 10.1128/JVI.72.6.4756-4764.1998
Lindemans, 2006, Systemic eosinophil response induced by respiratory syncytial virus., Clin Exp Immunol, 144, 409, 10.1111/j.1365-2249.2006.03084.x
Hemmi, 2003, The roles of Toll-like receptor 9, MyD88, and DNA-dependent protein kinase catalytic subunit in the effects of two distinct CpG DNAs on dendritic cell subsets., J Immunol, 170, 3059, 10.4049/jimmunol.170.6.3059
Creagh, 2006, TLRs, NLRs and RLRs: a trinity of pathogen sensors that co-operate in innate immunity., Trends Immunol, 27, 352, 10.1016/j.it.2006.06.003
Honda, 2005, IRF-7 is the master regulator of type-I interferon-dependent immune responses., Nature, 434, 772, 10.1038/nature03464
Marie, 1998, Differential viral induction of distinct interferon-alpha genes by positive feedback through interferon regulatory factor-7., EMBO J, 17, 6660, 10.1093/emboj/17.22.6660
Honda, 2006, Type I interferon [correction of inteferon] gene induction by the interferon regulatory factor family of transcription factors., Immunity, 25, 349, 10.1016/j.immuni.2006.08.009
Wark, 2005, Asthmatic bronchial epithelial cells have a deficient innate immune response to infection with rhinovirus., J Exp Med, 201, 937, 10.1084/jem.20041901
Contoli, 2006, Role of deficient type III interferon-lambda production in asthma exacerbations., Nat Med, 12, 1023, 10.1038/nm1462
Kurt-Jones, 2000, Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus., Nat Immunol, 1, 398, 10.1038/80833
Ehl, 2004, The role of Toll-like receptor 4 versus interleukin-12 in immunity to respiratory syncytial virus., Eur J Immunol, 34, 1146, 10.1002/eji.200324449
Faisca, 2006, Suppression of pattern-recognition receptor TLR4 sensing does not alter lung responses to pneumovirus infection., Microbes Infect, 8, 621, 10.1016/j.micinf.2005.08.010
Kim, 1969, Respiratory syncytial virus disease in infants despite prior administration of antigenic inactivated vaccine., Am J Epidemiol, 89, 422, 10.1093/oxfordjournals.aje.a120955
Wardlaw, 1987, The role of the eosinophil in the pathogenesis of asthma., Allergy, 42, 321, 10.1111/j.1398-9995.1987.tb02218.x
Gleich, 2000, Mechanisms of eosinophil-associated inflammation., J Allergy Clin Immunol, 105, 651, 10.1067/mai.2000.105712
Flood-Page, 2003, Eosinophil's role remains uncertain as anti-interleukin-5 only partially depletes numbers in asthmatic airway., Am J Respir Crit Care Med, 167, 199, 10.1164/rccm.200208-789OC
Kay, 2005, The role of eosinophils in the pathogenesis of asthma., Trends Mol Med, 11, 148, 10.1016/j.molmed.2005.02.002
Mattes, 2002, Intrinsic defect in T cell production of interleukin (IL)-13 in the absence of both IL-5 and eotaxin precludes the development of eosinophilia and airways hyperreactivity in experimental asthma., J Exp Med, 195, 1433, 10.1084/jem.20020009
Tsutsumi, 1999, Respiratory syncytial virus infection of human respiratory epithelial cells enhances inducible nitric oxide synthase gene expression., J Leukoc Biol, 66, 99, 10.1002/jlb.66.1.99
Ali-Ahmad, 2003, Replication of respiratory syncytial virus is inhibited in target cells generating nitric oxide in situ., Front Biosci, 8, a48, 10.2741/986
Stark, 2005, Immune and functional role of nitric oxide in a mouse model of respiratory syncytial virus infection., J Infect Dis, 191, 387, 10.1086/427241