MGMTGene Silencing and Benefit from Temozolomide in Glioblastoma

New England Journal of Medicine - Tập 352 Số 10 - Trang 997-1003 - 2005
Monika E. Hegi1,2, Annie‐Claire Diserens1, Thierry Gorlia3, Marie‐France Hamou1, Nicolas de Tribolet4,1, Michael Weller5, Johan M. Kros6, Johannes A. Hainfellner7, Warren Mason8, Luigi Mariani9, Jacoline E C Bromberg10, Peter Hau11, R.O. Mirimanoff12, J. Gregory Cairncross13, Robert C. Janzer14, Roger Stupp15
1Laboratory of Tumor Biology and Genetics, Department of Neurosurgery
2National Center of Competence in Research Molecular Oncology, Swiss Institute for Experimental Cancer Research, Epalinges
3Data Center, European Organisation for Research and Treatment of Cancer, Brussels
4Department of Neurosurgery, University Hospital Geneva, Geneva
5Department of Neurology, University of Tübingen, Tübingen
6Division of Neuropathology, University Hospital Rotterdam, Rotterdam
7Institute of Neurology, Medical University of Vienna, Vienna
8Princess Margaret Hospital, Toronto
9Department of Neurosurgery, Inselspital, Bern
10University Medical Center Utrecht
11Department of Neurology, University of Regensburg, Regensburg
12Departments of Radiotherapy
13University of Calgary, Calgary, Alta.
14Neuropathology
15Multidisciplinary Oncology Center, University Hospital Lausanne, Lausanne

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