CYP2C19*2 Polymorphism is Associated with Increased Survival in Breast Cancer Patients Using Tamoxifen
Tóm tắt
Từ khóa
Tài liệu tham khảo
Lien EA , SolheimE, KvinnslandS, UelandPM: Identification of 4-hydroxy-n-desmethyltamoxifen as a metabolite of tamoxifen in human bile.Cancer Res.48(8), 2304–2308 (1988).
Dehal SS , KupferD: CYP2D6 catalyzes tamoxifen 4-hydroxylation in human liver.Cancer Res.57(16), 3402–3406 (1997).
Poon GK , ChuiYC, MccagueR et al.: Analysis of phase I and phase II metabolites of tamoxifen in breast cancer patients.Drug Metab. Dispos.21(6), 1119–1124 (1993).
Serrano D , LazzeroniM, ZambonCF et al.: Efficacy of tamoxifen based on cytochrome p450 2D6, CYP2C19 and SULT1A1 genotype in the italian tamoxifen prevention trial.Pharmacogenomics J. (2010) (Epub ahead of print).
Berns P KokM SweepF et al.: CYP-2C19*2 predicts favorable outcome of tamoxifen treatment for advanced breast cancer. 32nd Annual CTRC-AACR San Antonio Breast Cancer Symposium (2009).
WHO international statistical classification of diseases and related health problems 10th revision (1992) www.who.int/classifications/icd/en