β-Defensins: Endogenous Antibiotics of the Innate Host Defense Response

Clinical Immunology and Immunopathology - Tập 88 Số 3 - Trang 221-225 - 1998
Gill Diamond1, Charles Bevins
1Department of Anatomy, Cell Biology and Injury Sciences, UMDNJ-New Jersey Medical School, Newark, New Jersey, 07103, USA.

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Tài liệu tham khảo

Hancock, 1995, Cationic bacterial peptides, Adv. Microb. Physiol., 37, 135, 10.1016/S0065-2911(08)60145-9

Boman, 1995, Peptide antibiotics and their role in innate immunity, Annu. Rev. Immunol., 13, 61, 10.1146/annurev.iy.13.040195.000425

Lehrer, 1996, Endogenous vertebrate antibiotics: Defensins, protegrins, and other cysteine-rich antimicrobial peptides, Ann. N.Y. Acad. Sci., 797, 228, 10.1111/j.1749-6632.1996.tb52963.x

Ganz, 1995, Defensins, Pharmacol. Ther., 66, 191, 10.1016/0163-7258(94)00076-F

Martin, 1995, Defensins and other endogenous peptide antibiotics of vertebrates, J. Leukocyte Biol., 58, 128, 10.1002/jlb.58.2.128

Diamond, 1991, Tracheal antimicrobial peptide, a novel cysteine-rich peptide from mammalian tracheal mucosa: Peptide isolation and cloning of a cDNA, Proc. Natl. Acad. Sci. USA, 88, 3952, 10.1073/pnas.88.9.3952

Selsted, 1983, Primary structures of MCP-1 and MCP-2, natural peptide antibiotics of rabbit lung macrophages, J. Biol. Chem., 258, 14485, 10.1016/S0021-9258(17)43888-9

Daher, 1988, Isolation and characterization of human defensin cDNA clones, Proc. Natl. Acad. Sci. USA, 85, 7327, 10.1073/pnas.85.19.7327

Valore, 1992, Posttranslational processing of defensins in immature human myeloid cells, Blood, 79, 1538, 10.1182/blood.V79.6.1538.1538

Selsted, 1984, Purification and antibacterial activity of antimicrobial peptides of rabbit granulocytes, Infect. Immun., 45, 150, 10.1128/IAI.45.1.150-154.1984

Ganz, 1985, Defensins: Natural peptide antibiotics of human neutrophils, J. Clin. Invest., 76, 1427, 10.1172/JCI112120

Lehrer, 1985, Direct inactivation of viruses by MCP-1 and MCP-2, natural peptide antibiotics from rabbit leukocytes, J. Virol., 54, 467, 10.1128/JVI.54.2.467-472.1985

Lehrer, 1988, Oxygen-independent bactericidal systems: Mechanisms and disorders, Hematol. Oncol. Clin. North Am., 2, 159, 10.1016/S0889-8588(18)30635-X

Ganz, 1990, Defensins, Eur. J. Haematol, 44, 1, 10.1111/j.1600-0609.1990.tb00339.x

Jones, 1992, Paneth cells of the human small intestine express an antimicrobial peptide gene, J. Biol. Chem., 267, 23216, 10.1016/S0021-9258(18)50079-X

Ouellette, 1996, Paneth cell defensins: Endogenous peptide components of intestinal host defense, FASEB J., 10, 1280, 10.1096/fasebj.10.11.8836041

Quayle, 1998, Gene expression, immunolocalization and secretion of human defensin-5 in human female genital tract, Am. J. Pathol., 152, 1247

Diamond, 1993, Airway epithelial cells are the site of expression of a mammalian antimicrobial peptide gene, Proc. Nat. Acad. Sci. USA, 90, 4596, 10.1073/pnas.90.10.4596

Selsted, 1993, Purification, primary structures, and antibacterial activities of beta-defensins, a new family of antimicrobial peptides from bovine neutrophils, J. Biol. Chem., 268, 6641, 10.1016/S0021-9258(18)53298-1

Tang, 1993, Characterization of the disulfide motif in BNBD-12, an antimicrobial beta-defensin peptide from bovine neutrophils, J. Biol. Chem., 268, 6649, 10.1016/S0021-9258(18)53299-3

Zimmermann, 1995, Solution structure of bovine neutrophil β-defensin-12: The peptide fold of the β-defensins is identical to that of classical defensins, Biochemistry, 34, 13663, 10.1021/bi00041a048

Schonwetter, 1995, Epithelial antibiotics induced at sites of inflammation, Science, 267, 1645, 10.1126/science.7886453

Russell, 1996, Coordinate induction of two antibiotic genes in tracheal epithelial cells exposed to the inflammatory mediators lipopolysaccharide and tumor necrosis factor alpha, Infect. Immun., 64, 1565, 10.1128/IAI.64.5.1565-1568.1996

Tarver, 1998, Enteric β-defensin: Molecular cloning and characterization of a gene with inducible intestinal epithelial cell expression associated withCryptosporidium parvum, Infect. Immun., 66, 1045, 10.1128/IAI.66.3.1045-1056.1998

Ryan, 1998, Expression of beta-defensin genes in bovine alveolar macrophages, Infect. Immun., 66, 878, 10.1128/IAI.66.2.878-881.1998

Harwig, 1994, Gallinacins: Cysteine-rich antimicrobial peptides of chicken leukocytes, FEBS Lett., 342, 281, 10.1016/0014-5793(94)80517-2

Evans, 1994, Isolation of antimicrobial peptides from avian heterophils, J. Leukocyte Biol., 56, 661, 10.1002/jlb.56.5.661

Bensch, 1995, hBD-1: A novel beta-defensin from human plasma, FEBS Lett., 368, 331, 10.1016/0014-5793(95)00687-5

Valore, 1998, Human β-defensin-1: An antimicrobial peptide of urogenital tissues, J. Clin. Invest., 101, 1633, 10.1172/JCI1861

Harder, 1997, A peptide antibiotic from human skin, Nature, 387, 861, 10.1038/43088

Morrison, 1998, Mouse beta defensin-1 is a functional homolog of human beta defensin-1, Mamm. Genome, 9, 453, 10.1007/s003359900795

Huttner, 1997, The mouse genome encodes a single homolog of the antimicrobial peptide human beta-defensin 1, FEBS Lett., 413, 45, 10.1016/S0014-5793(97)00875-2

Bals, 1998, Mouse β-defensin 1 is a salt-sensitive antimicrobial peptide present in epithelia of the lung and urogenital tract, Infect. Immun., 66, 1225, 10.1128/IAI.66.3.1225-1232.1998

Zhang, 1998, Molecular cloning and tissue expression of procine β-defensin-1, FEBS Lett., 424, 37, 10.1016/S0014-5793(98)00134-3

Huttner, 1998, Antimicrobial peptide expression is developmentally-regulated in the ovine gastrointestinal tract, J. Nutr., 128, 297S, 10.1093/jn/128.2.297S

Liu, 1997, The human β-defensin-1 and α-defensins are encoded by adjacent genes: Two peptide families with differing disulfide topology share a common ancestry, Genomics, 43, 316, 10.1006/geno.1997.4801

Sparkes, 1989, Assignment of defensin gene(s) to human chromosome 8p23, Genomics, 5, 240, 10.1016/0888-7543(89)90052-9

Bevins, 1996, Human enteric defensin genes: Chromosomal map position and a model for possible evolutionary relationships, Genomics, 31, 95, 10.1006/geno.1996.0014

Ouellette, 1989, Localization of the cryptdin locus on mouse chromosome 8, Genomics, 5, 233, 10.1016/0888-7543(89)90051-7

Gallagher, 1995, Somatic cell mapping of beta-defensin genes to cattle syntenic group U25 and fluoresence in situ localization to chromosome 27, Mamm. Genome, 6, 554, 10.1007/BF00356177

Huttner, 1998, Localization and genomic organization of sheep antimicrobial peptide genes, Gene, 206, 85, 10.1016/S0378-1119(97)00569-6

Iannuzzi, 1996, High resolution FISH mapping of beta-defensin genes to river buffalo and sheep chromosomes suggests a chromosome discrepancy in cattle standard karyotypes, Mamm. Genet., 75, 10

Diamond, 1996, Inducible expression of an antibiotic peptide gene in lipopolysaccharide-challenged tracheal epithelial cells, Proc. Natl. Acad. Sci. USA, 93, 5156, 10.1073/pnas.93.10.5156

Stolzenberg, 1997, Epithelial antibiotic induced in states of disease, Proc. Natl. Acad. Sci. USA, 94, 8686, 10.1073/pnas.94.16.8686

Bevins, 1996, Inducible expression of a mammalian antibiotic peptide gene in tracheal cells, Pediatr. Pulmon., Suppl.

Zhao, 1996, Widespread expression of beta-defensin hBD-1 in human secretory glands and epithelial cells, FEBS Lett., 396, 319, 10.1016/0014-5793(96)01123-4

McCray, 1997, Human airway epithelia express a beta-defensin, Am. J. Respir. Cell. Mol. Biol., 16, 343, 10.1165/ajrcmb.16.3.9070620

Goldman, 1997, Human β-defensin-1 is a salt-sensitive antibiotic in lung that is inactivated in cystic fibrosis, Cell, 88, 553, 10.1016/S0092-8674(00)81895-4

Yarus, 1996, Production of active bovine tracheal antimicrobial peptide in milk of transgenic mice, Proc. Natl. Acad. Sci. USA, 93, 14118, 10.1073/pnas.93.24.14118

Selsted, 1989, Determination of the disulfide array in the human defensin HNP-2. A covalently cyclized peptide, J. Biol. Chem., 264, 4003, 10.1016/S0021-9258(19)84952-9