Testing structural models of psychopathology at the genomic levelWorld Psychiatry - Tập 19 Số 3 - Trang 350-359 - 2020
Irwin D. Waldman, Holly E. Poore, Justin M. Luningham, Jingjing Yang
Genome‐wide association studies (GWAS) have revealed hundreds of genetic loci
associated with the vulnerability to major psychiatric disorders, and post‐GWAS
analyses have shown substantial genetic correlations among these disorders. This
evidence supports the existence of a higher‐order structure of psychopathology
at both the genetic and phenotypic levels. Despite recent efforts by
collaborative... hiện toàn bộ
Intergenerational transmission of trauma effects: putative role of epigenetic mechanismsWorld Psychiatry - Tập 17 Số 3 - Trang 243-257 - 2018
Rachel Yehuda, Amy Lehrner
This paper reviews the research evidence concerning the intergenerational
transmission of trauma effects and the possible role of epigenetic mechanisms in
this transmission. Two broad categories of epigenetically mediated effects are
highlighted. The first involves developmentally programmed effects. These can
result from the influence of the offspring's early environmental exposures,
including po... hiện toàn bộ
Diagnosis and classification of disorders specifically associated with stress: proposals for ICD-11World Psychiatry - Tập 12 Số 3 - Trang 198-206 - 2013
And re as Maercker, Chris R. Brewin, Richard A. Bryant, Marylène Cloître, Mark van Ommeren, Lynne Jones, Asma Humayan, Ashraf Kagee, Augusto E. Llosa, Cécile Rousseau, Daya Somasundaram, R. R. de Souza, Yuriko Suzuki, Inka Weissbecker, Simon Wessely, Michael B. First, Geoffrey M. Reed
“Prolonged grief disorder” and “persistent complex bereavement disorder”, but not “complicated grief”, are one and the same diagnostic entity: an analysis of data from the Yale Bereavement StudyWorld Psychiatry - Tập 15 Số 3 - Trang 266-275 - 2016
Paul K. Maciejewski, And re as Maercker, Paul A. Boelen, Holly G. Prigerson
There exists a general consensus that prolonged grief disorder (PGD), or some
variant of PGD, represents a distinct mental disorder worthy of diagnosis and
treatment. Nevertheless, confusion remains over whether different names and
proposed symptom criteria for this disorder identify the same or different
diagnostic entities. This study aimed to determine whether PGD, complicated
grief (CG), and p... hiện toàn bộ