Wiley
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Surface modification by alkali and heat treatments in titanium alloys
Wiley - Tập 61 Số 3 - Trang 466-473 - 2002
AbstractPure titanium and titanium alloys are normally used for orthopedic and
dental prostheses. Nevertheless, their chemical, biological, and mechanical
properties still can be improved by the development of new preparation
technologies. This has been the limiting factor for these metals to show low
affinity to living bone. The purpose of this study is to improve the
bone‐bonding ability between...
Diffusive and convective solute transport through hemodialysis membranes: A hydrodynamic analysis
Wiley - Tập 28 Số 5 - Trang 573-582 - 1994
AbstractRecent clinical studies have shown that the overall effectiveness of
hemodialysis is determined by both the convective and diffusive transport of a
wide range of different molecular weight solutes. In this study, transport data
were obtained for vitamin B12 and for polydisperse dextrans with a wide range of
molecular weights using flat sheet Cuprophan and AN69 polyacrylonitrile
membranes. ...
Neocartilage formation in vitro and in vivo using cells cultured on synthetic biodegradable polymers
Wiley - Tập 27 Số 1 - Trang 11-23 - 1993
AbstractCartilaginous implants for potential use in reconstructive or orthopedic
surgery were created using chondrocytes grown on synthetic, biodegradable
polymer scaffolds. Chondrocytes isolated from bovine or human articular or
costal cartilage were cultured on fibrous polyglycolic acid (PGA) and porous
poly(L)lactic acid (PLLA) and used in parallel in vitro and in vivo studies.
Samples were tak...
Bioerodible polyanhydrides as drug‐carrier matrices. I: Characterization, degradation, and release characteristics
Wiley - Tập 19 Số 8 - Trang 941-955 - 1985
AbstractPolyanhydrides based on a variety of aromatic and aliphatic dicarboxylic
acids were developed as bioerodible carrier matrices for controlled delivery
applications. The high hydrolytic reactivity of the anhydride linkage provides
an intrinsic advantage over other classes of bioerodible polymers in versatility
and control of degradation rates. For example, using the
poly[bis(p‐carboxyphenoxy...
Competitive adsorption of albumin against collagen at solution–air and solution–polythylene interfaces
Wiley - Tập 27 Số 2 - Trang 145-152 - 1993
AbstractThe adsorption of human serum albumin (HSA) from the binary mixtures
with collagen was monitored at solution–air and solution–polyethylene interfaces
by the in situ measurements. The results clearly demonstrate that on both
interfaces albumin is the only adsorbing protein within a large collagen
solution concentration range. At the albumin concentration equal to 0.005 mg/mL,
the presence o...
Collagen at interfaces I. In situ collagen adsorption at solution/air and solution/polymer interfaces
Wiley - Tập 20 Số 7 - Trang 951-962 - 1986
AbstractCollagen was isolated from rat tail tendons and acetylated with 1–14C
acetic anhydride. In situ adsorption of this collagen from a buffer solution (pH
= 2.7) was measured at the interfaces to air, polyethylene and polyethylene
grafted with poly(maleic acid), respectively.The kinetics of adsorption were
recorded for all surfaces studied and the corresponding diffusion coefficients
for colla...
Collagen at interfaces II: Competitive adsorption of collagen against albumin and fibrinogen
Wiley - Tập 21 Số 3 - Trang 321-328 - 1987
AbstractAdsorption of chemically radiolabeled [14C] collagen from binary
mixtures with albumin or fibrinogen was studied on the solution/air and
solution/polyethylene interfaces and revealed the preferential adsorption of
albumin. This phenomenon is confirmed by the data of surface tension
measurements of single protein, collagen‐albumin, and collagen‐fibrinogen
solutions. Desorption experiments c...
In situ gelling and mucoadhesive polymer vehicles for controlled intranasal delivery of plasmid DNA
Wiley - Tập 59 Số 1 - Trang 144-151 - 2002
AbstractNasal administration of plasmid DNA is emerging as a new route of
delivery for therapeutic genes and DNA vaccines. To improve the intranasal
absorption of plasmid DNA, we designed delivery systems composed of in situ
gelling and mucoadhesive polymers. Poloxamers (Pol) were used to provide in situ
gelling property. Polycarbophil (PC) or polyethylene oxide (PEO) was used as
mucoadhesive poly...
A new absorbable suture
Wiley - Tập 5 Số 2 - Trang 43-58 - 1971
AbstractAlthough satisfactory nonabsorbable sutures made from a variety of
synthetic and natural materials have been available for a number of years, since
ancient times only collagenous absorbable sutures have found general acceptance.
While adequate, catgut and the more recently developed regenerated collagens
have inherent disadvantages common to many complex natural substances,
particularly va...
Degradation rates of oral resorbable implants (polylactates and polyglycolates): Rate modification with changes in PLA/PGA copolymer ratios
Wiley - Tập 11 Số 5 - Trang 711-719 - 1977
AbstractThis study determined the difference in rate of degradation between pure
polymers of lactic acid (PLA), glycolic acid (PGA), and various ratios of
copolymers of these two substances. Fast‐cured and slow‐cured polyglycolide was
compared with copolymers of glycolide/lactide intermixed in ratios of 75:25,
50:50, and 25:75, as well as pure polylactide. A total of 420 rats were
implanted with c...
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