Wiley
1080-4013
1098-2779
Cơ quản chủ quản: N/A
Lĩnh vực:
Các bài báo tiêu biểu
A cascade of disparities: Health and health care access for people with intellectual disabilitiesAbstract People with ID represent approximately 2% of the population and, as a group, experience poorer health than the general population. This article presents recent conceptualizations that begin to disentangle health from disability, summarizes the literature from 1999 to 2005 in terms of the cascade of disparities, reviews intervention issues and promising prac... ...
Tập 12 Số 1 - Trang 70-82 - 2006
Epidemiology of Down syndromeAbstract Down syndrome (DS) is the most commonly identified genetic form of mental retardation and the leading cause of specific birth defects and medical conditions. Traditional epidemiological studies to determine the prevalence, cause, and clinical significance of the syndrome have been conducted over the last 100 years. DS has been estimated to occur in ∼1 in 73... ...
Tập 13 Số 3 - Trang 221-227 - 2007
Cognitive and neuropsychological outcomes: More than IQ scoresAbstract Improved survival in preterm infants has broadened interest in cognitive and neuropsychological outcomes. The incidence of major disabilities (moderate/severe mental retardation, neurosensory disorders, epilepsy, cerebral palsy) has remained consistent, but high prevalence/low severity dysfunctions (learning disabilities, ADHD, borderline mental retardation... ...
Tập 8 Số 4 - Trang 234-240 - 2002
Early intervention after universal neonatal hearing screening: Impact on outcomesAbstract This article summarizes the developmental outcomes of Colorado children with significant hearing loss. Some of the research compares children born in hospitals that have implemented universal newborn hearing screening programs for newborns. Other research compares the developmental outcomes of children who have been early‐identified with hearing loss. Early... ...
Tập 9 Số 4 - Trang 252-266 - 2003
Phenotypic variation and FMRP levels in fragile XAbstract Data on the relationships between cognitive and physical phenotypes, and a deficit of fragile X mental retardation 1 (FMR1) gene‐specific protein product, FMRP, are presented and discussed in context with earlier findings. The previously unpublished results obtained, using standard procedures of regression and correlations, showed highly significant associa... ...
Tập 10 Số 1 - Trang 31-41 - 2004
Alzheimer's disease in Down syndrome: Neurobiology and riskAbstract Down syndrome (DS) is characterized by increased mortality rates, both during early and later stages of life, and age‐specific mortality risk remains higher in adults with DS compared with the overall population of people with mental retardation and with typically developing populations. Causes of increased mortality rates early in life are primarily due to... ...
Tập 13 Số 3 - Trang 237-246 - 2007
Psychiatric and behavioral disorders in persons with Down syndromeAbstract Similar to the state of the broader intellectual disabilities field, many gaps exist in the research and treatment of mental health concerns in people with Down syndrome. This review summarizes key findings on the type and prevalence of behavior and emotional problems in children, adolescents, and adults with Down syndrome. Such findings include relatively ... ...
Tập 13 Số 3 - Trang 272-278 - 2007
Toward a developmental neurobiology of autismAbstract Autism is a complex, behaviorally defined, developmental brain disorder with an estimated prevalence of 1 in 1,000. It is now clear that autism is not a disease, but a syndrome with a strong genetic component. The etiology of autism is poorly defined both at the cellular and the molecular levels. Based on the fact that seizure activity is frequently associa... ...
Tập 10 Số 4 - Trang 303-317 - 2004
Apoptosis and brain developmentAbstract Neuronal cell death in the embryonic brain was first recognized almost a century ago. Its significance for normal nervous system development and function has been a major focus of neuroscientific investigation ever since. Remarkable progress has been made in defining the cellular processes controlling neuronal cell death and studies performed over the last ... ...
Tập 7 Số 4 - Trang 261-266 - 2001
Sexual health care in persons with intellectual disabilitiesAbstract In the past, preventive health concerning sexuality of people with intellectual disabilities was addressed through surgical sterilization as part of nationwide eugenic programs in many countries. For more than 30 years now, it has come progressively to light in the scientific literature that, besides major ethical and legal problems, these programs also fai... ...
Tập 12 Số 1 - Trang 48-56 - 2006