Wiley
SCOPUS (1995-2007)
1080-4013
1098-2779
Cơ quản chủ quản: N/A
Phân tích ảnh hưởng
Các bài báo tiêu biểu
A cascade of disparities: Health and health care access for people with intellectual disabilities
Tập 12 Số 1 - Trang 70-82 - 2006
AbstractPeople with ID represent approximately 2% of the population and, as a
group, experience poorer health than the general population. This article
presents recent conceptualizations that begin to disentangle health from
disability, summarizes the literature from 1999 to 2005 in terms of the cascade
of disparities, reviews intervention issues and promising practices, and
provides recommendatio...
Epidemiology of Down syndrome
Tập 13 Số 3 - Trang 221-227 - 2007
AbstractDown syndrome (DS) is the most commonly identified genetic form of
mental retardation and the leading cause of specific birth defects and medical
conditions. Traditional epidemiological studies to determine the prevalence,
cause, and clinical significance of the syndrome have been conducted over the
last 100 years. DS has been estimated to occur in ∼1 in 732 infants in the
United States, a...
Cognitive and neuropsychological outcomes: More than IQ scores
Tập 8 Số 4 - Trang 234-240 - 2002
AbstractImproved survival in preterm infants has broadened interest in cognitive
and neuropsychological outcomes. The incidence of major disabilities
(moderate/severe mental retardation, neurosensory disorders, epilepsy, cerebral
palsy) has remained consistent, but high prevalence/low severity dysfunctions
(learning disabilities, ADHD, borderline mental retardation, specific
neuropsychological def...
Early intervention after universal neonatal hearing screening: Impact on outcomes
Tập 9 Số 4 - Trang 252-266 - 2003
AbstractThis article summarizes the developmental outcomes of Colorado children
with significant hearing loss. Some of the research compares children born in
hospitals that have implemented universal newborn hearing screening programs for
newborns. Other research compares the developmental outcomes of children who
have been early‐identified with hearing loss. Early‐identification is defined as
ide...
Phenotypic variation and FMRP levels in fragile X
Tập 10 Số 1 - Trang 31-41 - 2004
AbstractData on the relationships between cognitive and physical phenotypes, and
a deficit of fragile X mental retardation 1 (FMR1) gene‐specific protein
product, FMRP, are presented and discussed in context with earlier findings. The
previously unpublished results obtained, using standard procedures of regression
and correlations, showed highly significant associations in males between FMRP
level...
Alzheimer's disease in Down syndrome: Neurobiology and risk
Tập 13 Số 3 - Trang 237-246 - 2007
AbstractDown syndrome (DS) is characterized by increased mortality rates, both
during early and later stages of life, and age‐specific mortality risk remains
higher in adults with DS compared with the overall population of people with
mental retardation and with typically developing populations. Causes of
increased mortality rates early in life are primarily due to the increased
incidence of conge...
Psychiatric and behavioral disorders in persons with Down syndrome
Tập 13 Số 3 - Trang 272-278 - 2007
AbstractSimilar to the state of the broader intellectual disabilities field,
many gaps exist in the research and treatment of mental health concerns in
people with Down syndrome. This review summarizes key findings on the type and
prevalence of behavior and emotional problems in children, adolescents, and
adults with Down syndrome. Such findings include relatively low rates of severe
problems in c...
Toward a developmental neurobiology of autism
Tập 10 Số 4 - Trang 303-317 - 2004
AbstractAutism is a complex, behaviorally defined, developmental brain disorder
with an estimated prevalence of 1 in 1,000. It is now clear that autism is not a
disease, but a syndrome with a strong genetic component. The etiology of autism
is poorly defined both at the cellular and the molecular levels. Based on the
fact that seizure activity is frequently associated with autism and that
abnormal...
Apoptosis and brain development
Tập 7 Số 4 - Trang 261-266 - 2001
AbstractNeuronal cell death in the embryonic brain was first recognized almost a
century ago. Its significance for normal nervous system development and function
has been a major focus of neuroscientific investigation ever since. Remarkable
progress has been made in defining the cellular processes controlling neuronal
cell death and studies performed over the last ten years have revealed extensive...
Sexual health care in persons with intellectual disabilities
Tập 12 Số 1 - Trang 48-56 - 2006
AbstractIn the past, preventive health concerning sexuality of people with
intellectual disabilities was addressed through surgical sterilization as part
of nationwide eugenic programs in many countries. For more than 30 years now, it
has come progressively to light in the scientific literature that, besides major
ethical and legal problems, these programs also failed to assess many of the
individ...