Wiley
SCOPUS (1995-2007)
1080-563X
1527-3458
Cơ quản chủ quản: N/A
Các bài báo tiêu biểu
Pharmacological Profile of the Selective FAAH Inhibitor KDS-4103 (URB597)
Tập 12 Số 1 - Trang 21-38 - 2006
Ethosuximide: From Bench to Bedside
Tập 13 Số 2 - Trang 224-239 - 2007
ABSTRACTEthosuximide, 2‐ethyl‐2‐methylsuccinimide, has been used extensively for
“petit mal” seizures and it is a valuable agent in studies of absence epilepsy.
In the treatment of epilepsy, ethosuximide has a narrow therapeutic profile. It
is the drug of choice in the monotherapy or combination therapy of children with
generalized absence (petit mal) epilepsy. Commonly observed side effects of
et...
Levetiracetam: Part II, the Clinical Profile of a Novel Anticonvulsant Drug
Tập 13 Số 1 - Trang 57-78 - 2007
ABSTRACTThe objective of this article was to review and summarize the available
reports on the profile of the novel anticonvulsant drug levetiracetam (LEV) in a
clinical setting. Therefore, a careful search was conducted in the MEDLINE
database and combined with guidelines from regulatory agencies, proceedings of
professional scientific meetings, and information provided by the manufacturers.
This...
Mildronate: An Antiischemic Drug for Neurological Indications
Tập 11 Số 2 - Trang 151-168 - 2005
ABSTRACTMildronate (3‐(2,2,2‐trimethylhydrazinium)propionate; MET‐88; meldonium,
quaterine) is an antiischemic drug developed at the Latvian Institute of Organic
Synthesis. Mildronate was designed to inhibit carnitine biosynthesis in order to
prevent accumulation of cytotoxic intermediate products of fatty acid
β‐oxidation in ischemic tissues and to block this highly oxygen‐consuming
process. Mild...
Glatiramer Acetate in Multiple Sclerosis: A Review
Tập 13 Số 2 - Trang 178-191 - 2007
ABSTRACTMultiple sclerosis (MS) is considered to be primarily an inflammatory
autoimmune disease. Over the last 5 years, our view of the pathogenesis of MS
has evolved considerably. The axonal damage was recognized as an early event in
the disease process and as an important determinant of long‐term disability.
Therefore, the antiinflammatory and neuroprotective strategies are thought to
represent...
MDL 100,907: A Selective 5‐HT2A Receptor Antagonist for the Treatment of Schizophrenia
Tập 3 Số 1 - Trang 49-67 - 1997