Wiley
0036-553X
Cơ quản chủ quản: N/A
Các bài báo tiêu biểu
Familial Leukaemia: A Study of 909 FamiliesA family survey was conducted among 909 patients with leukaemia of all types, with the purpose of establishing the incidence of further cases of leukaemia among relatives. Among a total of 41,807 relatives 8,349 were deceased, and the cause of death was objectively confirmed in 5,011. 72 patients had one or more relatives with leukaemia. First degree relativ... ...
Tập 15 Số 2 - Trang 117-131 - 1975
The Platelet Aggregating Effect of Eight Commercial HeparinsEight commercial heparin preparations were examined by the method of Born & Cross. All preparations induced aggregation of washed human platelets in the presence of calcium, probably by inducing release of platelet ADP. The aggregating potency varied considerably from brand to brand.
Tập 9 Số 1-6 - Trang 480-482 - 1972
The Value of Preoperative Haemostatic ScreeningThe value of preoperative haemostatic screening tests in prediction of surgical bleeding was examined in 101 patients, mainly with abdominal and thyroid lesions. The study demonstrated complete lack of correlation between the preoperative evaluation of bleeding risk and the observed surgical bleeding (X2 test P ∼ 0.85).
Tập 21 Số 4 - Trang 349-354 - 1978
Immunochemical Properties of Cold HaemagglutininsIn six cases of the cold haemagglutinin syndrome, the isolated cold haemagglutinin was electrophoretically markedly homogeneous when compared with the total γ1 ‐macroglobulin of the same sera and consisted of group I molecules only. In three of the cases, individually specific antigenic determinants were demonstrated on the isolated cold haemagglutinin. These determinan... ...
Tập 1 Số 3 - Trang 223-237 - 1964
Periodic Thrombocytopenia or Tidal Platelet Dysgenesis in a ManThe authors describe the haematologic findings in a man aged 61, who for two years has been under observation with a syndrome of thrombocytopenia, regularly alternating with thrombocytosis of a very regular interval of 39 days. This tidal fluctuation of the platelet counts was within the range 10,000–900,000/μl. There was a synchronous fluctuation of the megakaryocyte numbers in the bone m... ...
Tập 3 Số 4 - Trang 290-294 - 1966
Cyclic Thrombocytopenia Case Report and Review of LiteratureA patient with cyclic changes in circulating platelet level is reported, and the literature on this cyclic phenomenon is discussed. Platelet and menstrual cycles occurred independently. In our patient and several others reviewed herein, the cycling of the platelet level is probably related to cyclic changes in platelet production. We speculate that these production changes result from the ... ...
Tập 12 Số 1 - Trang 9-17 - 1974
The great majority of childhood lymphoblastic leukaemias are identified by monoclonal antibodies as neoplasias of the B‐cell progenitor compartment36 acute leukaemias in children, 24 lymphoblastic and 14 myelogenic, have been examined with a set of 10 monoclonal antibodies by indirect fluorescent staining. In the lymphoblastic group the leukaemic cells of 4 children were found to have T‐cell phenotype, while 19 of the other 20 T‐cell phenotype negative cases were found to be positive for the c‐ALL antigen. All 20 were negative for su... ...
Tập 33 Số 1 - Trang 27-34 - 1984
Preleukaemic Abnormal Myelopoiesis Induced by Chlorambucil: A Case StudyThe authors report a patient treated for 3 years with chlorambucil for scleroderma. This apparently produced a preleukaemic sideroblastic anaemia and acute leukemia. This point out the consequences of the employment of immunodepressive agents.
Tập 13 Số 3 - Trang 179-183 - 1974
Acute Erythroleukaemia in a Patient treated with Melphalan for the Cold Agglutinin SyndromeIn a case of cold agglutinin syndrome, treatment with melphalan resulted in marked decrease of cold agglutinin titre, decrease in concentration of monoclonal cold agglutinin IgM, and concomitant clinical improvement with increased cold tolerance. After 27 months of melphalan treatment, the patient developed acute erythroleukaemia.
Tập 8 Số 5 - Trang 375-379 - 1971
Cyclic Thrombocytopenia of Acute TypeThis is a case report on a male technician, 37 years of age, who experienced 5 acute episodes of severe thrombocytopenia, which occurred regularly every 21st day. The bleeding episodes usually lasted 12 days, and the remissions 9 days. Treatment with corticosteroids and splenectomy had no influence upon the course of the disease. The bleeding became worse at every episode, and the patient ... ...
Tập 4 Số 5 - Trang 380-384 - 1967