Schnitzler's syndrome: lessons from 281 cases - 2014
Heleen D. de Koning
AbstractSchnitzler's syndrome is an autoinflammatory disorder characterized by
the association of a monoclonal IgM (or IgG) gammopathy, a chronic urticarial
rash, and signs and symptoms of systemic inflammation, including fever,
arthralgias and bone pain. It was first described in 1972. This review
summarizes the clinical features, efficacy of therapies, and follow‐up data of
the 281 cases that ha... hiện toàn bộ
Intact skin and not stripped skin is crucial for the safety and efficacy of peanut epicutaneous immunotherapy (EPIT) in mice Tập 2 Số 1 - 2012
Lucie Mondoulet, Vincent Dioszeghy, Emilie Puteaux, Mélanie Ligouis, Véronique Dhelft, Franck Letourneur, Christophe Dupont, Pierre‐Henri Benhamou
AbstractBackgroundEpicutaneous immunotherapy (EPIT) on intact skin with an
epicutaneous delivery system has already been used in preclinical and clinical
studies. In epicutaneous vaccination and immunotherapy, the stripping of skin
before application of the allergen is suggested to facilitate the passage of
allergen through immune cells.ObjectivesThe aim of this study was to compare the
immunologi... hiện toàn bộ
Allergy as an epithelial barrier disease Tập 1 Số 1 - 2011
Pirkko Mattila, Sakari Joenväärä, Jutta Renkonen, Sanna Toppila‐Salmi, Risto Renkonen
AbstractThe objective of this review is to focus on putative modified epithelial
functions related to allergy. The dysregulation of the epithelial barrier might
result in the allergen uptake, which could be the primary defect in the
pathogenesis of allergic reaction. We review the literature of the role of
respiratory epithelium as an active barrier, how allergens are transported
through it and ho... hiện toàn bộ
Immunological events in chronic spontaneous urticaria Tập 5 Số 1 - 2015
Marta Ferrer
AbstractChronic spontaneous urticaria (CSU) is a highly debilitating skin
disease associated with systemic features. We have made significant progress in
several aspects relating to this condition. However, the exact physiopathology
remains unknown. There is mounting evidence for an autoimmune basis,
demonstrated by the CSU serum ability to activate healthy donors skin mast cells
and blood basophi... hiện toàn bộ
Allergen sensitization linked to climate and age, not to intermittent‐persistent rhinitis in a cross‐sectional cohort study in the (sub)tropics - 2014
Désirée Larenas‐Linnemann, Alexandra Michels, Hanna Dinger, Kija Shah‐Hosseini, Ralph Mösges, Alfredo Arias-Cruz, Marichuy Ambriz-Moreno, Martín Bedolla-Barajas, R Cerino Javier, María de la Luz Cid del Prado, Manuel Alejandro Cruz Moreno, Roberto García Almaráz, Cecilia Yvonne García-Cobas, Daniel Alberto García Imperial, Rosa Garcia Muñoz, Dante Daniel Hernández-Colín, Francisco Javier Linares‐Zapién, Jorge A. Luna-Pech, Juan José Matta-Campos, Norma Martínez Jiménez, Miguel Alejandro Medina-Ávalos, Alejandra Medina Hernández, Alberto Monteverde Maldonado, Doris Nereida López, Luis Julian Pizano Nazara, Emmanuel Ramirez Sanchez, José Domingo Ramos-López, Noel Rodríguez-Pérez, Pablo Rodríguez-Ortiz
AbstractBackgroundAllergen exposure leads to allergen sensitization in
susceptible individuals and this might influence allergic rhinitis (AR)
phenotype expression. We investigated whether sensitization patterns vary in a
country with subtropical and tropical regions and if sensitization patterns
relate to AR phenotypes or age.MethodsIn a national, cross‐sectional study AR
patients (2‐70 y) seen b... hiện toàn bộ