Wiley
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Association of cold‐reactive antilymphocyte antibodies with lymphopenia in systemic lupus erythematosusAbstract In a prospective study 26 of 29 patients with systemic lupus erythematosus had cold‐reactive antilymphocyte antibodies cytotoxic for autologous lymphocytes and lymphocytes from normal subjects. The level of antilymphocyte antibodies was highly correlated, by linear regression analysis, with lymphopenia in these patients. The data suggested that both the avi... ... hiện toàn bộ
Wiley - Tập 18 Số 6 - Trang 587-594 - 1975
Measurement of increases in anti‐double‐stranded dna antibody levels as a predictor of disease exacerbation in systemic lupus erythematosusAbstract To evaluate the predictive power of changes in levels of antibodies to double‐stranded DNA (anti‐dsDNA) as a predictor of disease exacerbations in systemic lupus erythematosus (SLE), we performed a prospective study on 72 unselected patients with SLE (mean duration of study 18.5 months, range 6–35 months). Patients were seen at least once every 3 months, an... ... hiện toàn bộ
Wiley - Tập 33 Số 5 - Trang 634-643 - 1990
Evaluation of the efficacy and safety of pamapimod, a p38 MAP kinase inhibitor, in a double‐blind, methotrexate‐controlled study of patients with active rheumatoid arthritisAbstract Objective To determine the efficacy and safety of pamapimod (a selective inhibitor of the α‐isoform of p38 MAP kinase) as monotherapy in comparison with methotrexate (MTX) treatment in adult patients with active rheumatoid arthritis (RA). Methods Patients were ran... ... hiện toàn bộ
Wiley - Tập 60 Số 2 - Trang 335-344 - 2009
Distribution of HLA–B27 subtypes in Sardinia and continental Italy and their association with spondylarthropathies
Wiley - Tập 52 Số 10 - Trang 3319-3321 - 2005
Beneficial Effect of Artificial Tears Made with Autologous Serum in Patients with Keratoconjunctivitis Sicca
Wiley - Tập 27 Số 4 - Trang 459-461 - 1984
Cartilage repair using bone morphogenetic protein 4 and muscle‐derived stem cellsAbstract Objective Muscle‐derived stem cells (MDSCs) isolated from mouse skeletal muscle exhibit long‐time proliferation, high self‐renewal, and multipotent differentiation. This study was undertaken to investigate the ability of MDSCs that were retrovirally transduced to express bone morphogenetic protein 4 (BMP‐4) to differentiate... ... hiện toàn bộ
Wiley - Tập 54 Số 2 - Trang 433-442 - 2006
Interleukin‐6 modulates production of T lymphocyte–derived cytokines in antigen‐induced arthritis and drives inflammation‐induced osteoclastogenesisAbstract Objective To determine the cellular mediators of antigen‐induced arthritis (AIA) and the relative contribution of members of the interleukin‐6 (IL‐6) family and tumor necrosis factor (TNF) in AIA. Methods AIA was induced in mice deficient in T and B lymphocytes, I... ... hiện toàn bộ
Wiley - Tập 54 Số 1 - Trang 158-168 - 2006
Down‐regulation of myeloid cell leukemia 1 by epigallocatechin‐3‐gallate sensitizes rheumatoid arthritis synovial fibroblasts to tumor necrosis factor α–induced apoptosisAbstract Objective Overexpression of the antiapoptotic protein myeloid cell leukemia 1 (Mcl‐1) in rheumatoid arthritis (RA) synovial fibroblasts is a major cause of their resistance to tumor necrosis factor α (TNFα)–induced apoptosis. This study was undertaken to evaluate the efficacy of epigallocatechin‐3‐gallate (EGCG) in down‐reg... ... hiện toàn bộ
Wiley - Tập 60 Số 5 - Trang 1282-1293 - 2009
Cannabinoid‐mediated antinociception is enhanced in rat osteoarthritic kneesAbstract Objective To determine whether local administration of the cannabinoid 1 (CB1 ) receptor agonist arachidonyl‐2‐chloroethylamide (ACEA) can modulate joint nociception in control rat knee joints and in experimental osteoarthritis (OA). Methods OA... ... hiện toàn bộ
Wiley - Tập 58 Số 1 - Trang 145-153 - 2008
Broad‐spectrum matrix metalloproteinase inhibitor marimastat–induced musculoskeletal side effects in ratsAbstract Objective To characterize the clinical and histopathologic changes in a rat model of broad‐spectrum matrix metalloproteinase (MMP)–induced musculoskeletal syndrome (MSS), and to facilitate research into the causes and treatments of MSS in humans. Methods Male Lewi... ... hiện toàn bộ
Wiley - Tập 48 Số 6 - Trang 1742-1749 - 2003
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