Wiley

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Ap endonucleases and dna glycosylases that recognize oxidative dna damage
Wiley - Tập 12 Số 4 - Trang 431-477 - 1988
Susan S. Wallace
Salmonella mutagenicity test results for 250 chemicals
Wiley - Tập 5 Số S1 - Trang 3-49 - 1983
Steve Haworth, Timothy E. Lawlor, Kristien Mortelmans, William T. Speck, Errol Zeiger
Chromosome aberrations and sister chromatid exchanges in styrene‐exposed workers with reference to their smoking habits
Wiley - Tập 5 Số 3 - Trang 299-309 - 1983
Toshiaki Watanabe, Akira Endo, Miho Kumai, Masayuki Ikeda
AbstractThe incidences of chromosome aberrations and the frequencies of sister chromatid exchanges (SCE) were investigated in cultured lymphocytes of 18 styrene‐exposed workers in comparison with six controls. There was a marginal increase in the incidence of structural chromosomal aberrations in first‐division metaphases in the styrene‐exposed workers, as compared...... hiện toàn bộ
Lack of effect of dibromochloropropane on the mouse testis
Wiley - Tập 6 Số 4 - Trang 621-625 - 1984
E. F. Oakberg, C. C. Cummings
AbstractA single intraperitoneal injection of (101 x C3Hf)F male mice with 110 mg/kg of 1,2‐dibromo‐3‐chloropropane (DBCP) showed no effect on spermatogonial stem cells or on differentiating spermatogonia as measured by cell counts made 3, 5, and 8 days after injection.
The genetic toxicology of metal compounds: I. Induction of λ prophage in E coli WP2S(λ)
Wiley - Tập 6 Số 1 - Trang 59-69 - 1984
Toby G. Rossman, Margarita Molina, LeRoy W. Meyer
AbstractA number of metal compounds have been shown to be human carcinogens. Others, while not proven human carcinogens, are able to cause tumors in laboratory animals. Short‐term bacterial assays for genotoxic effects have not been successful in predicting the carcinogenicity of metal compounds. We report here the ability of some metal compounds to cause the induc...... hiện toàn bộ
Variation in the baseline sister chromatid exchange frequency in human lymphocytes
Wiley - Tập 2 Số 3 - Trang 325-337 - 1980
A.V. Carrano, J.L. Minkler, Daniel G. Stetka, Dan H. Moore
AbstractThe utility of the sister chromatid exchange (SCE) assay for human population studies is potentially limited by the variability associated with individual baseline SCE frequencies. This investigation identifies and quantifies the major sources of preparative and biological variation associated with the determination of baseline SCE frequencies in cultured h...... hiện toàn bộ
Sister chromatid exchanges in chines hamster cells treated with seventeen organophosphorus compounds in the presence of a metabolic activation system
Wiley - Tập 4 Số 5 - Trang 621-624 - 1982
H. H. Chen, S.R. Sirianni, C. C. Huang
AbstractThe mutagenicity of several organophosphorus pesticides (OPP) has been demonstrated by Wild [1975] in microorganisms. However, the results as reported in the literature of cytogenic, mutagenic, and carcinogenic tests using mammalian cells or experimental animals were scanty and inconclusive [Huang, 1973; Wild, 1975]. This may be partly due to the high toxic...... hiện toàn bộ
Somatic mutation and recombination test in Drosophila melanogaster
Wiley - Tập 6 Số 2 - Trang 153-188 - 1984
Ulrich Gräf, F.E. Würgler, Alan J. Katz, H. Frei, H. Juon, Caroline B. Hall, P.G. Kale
AbstractA novel test system for the detection of mutagenic and recombinogenic activity of chemicals is described in detail. Drosophila melanogaster larvae trans‐heterozygous for the mutations multiple wing hairs (mwh) and flare (fir) are exposed to the test compounds for various periods of time ranging from 96 hr to 1 hr. Induced mutation...... hiện toàn bộ
Pesticide‐induced complete and partial chromosome loss in screens with repair‐defective females of drosophila melanogaster
Wiley - Tập 5 Số 6 - Trang 835-846 - 1983
R. C. Woodruff, J. P. Phillips, David M. Irwin
AbstractCommercial preparation of fungicides (captan and maneb), herbicides (bromacil, paraquat, picloram, and 2,4‐D), and insecticides (carbaryl, chlorpyrifos, dimethoate, DDT, diazinon, carbofuran, and permethrin) were tested for their ability to induce complete and partial chromosome losses in Drosophila melanogaster males. In an attempt to identify the mutageni...... hiện toàn bộ
Sister chromatid exchange and chromosome aberration analyses in mice after in vivo exposure to acrylonitrile, styrene, or butadiene monoxide
Wiley - Tập 8 Số 3 - Trang 439-448 - 1986
Yousuf Sharief, Arthur Brown, Lorraine C. Backer, James A. Campbell, Barbara Westbrook‐Collins, Andrew G. Stead, James W. Allen
AbstractThe use of polymers in plastic and rubber products has generated concern that monomers potentially active in biological systems may be eluted from these substances. We have evaluated two such monomers, acrylonitrile and styrene, for the induction of chromosome damage in mice. Butadiene monoxide, a presumed metabolite of a third important monomer, 1,3‐butadi...... hiện toàn bộ
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