Wiley
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Multiple Serotonin Receptors: Opportunities for New Treatments for Obesity?Abstract Recent progress in the molecular pharmacology of 5‐HT receptors and the development of selective ligands for various 5‐HT receptor subtypes has advanced our understanding of the role of 5‐HT mechanisms in the control of food intake and body weight The most intensively investigated 5‐HT receptor subtypes have been the 5‐HT1A r... ... hiện toàn bộ
Wiley - Tập 3 Số S4 - 1995
Regulation of 11β‐HSD Genes in Human Adipose Tissue: Influence of Central Obesity and Weight LossAbstract Objectives : The activity of adipose 11β‐hydroxysteroid dehydrogenase (11β‐HSD) 1 is increased in obese subjects, and animal data suggest that increased cortisol formation in adipose tissue contributes to the development of the metabolic syndrome. The aim of this study was to determine whether up‐regulation of human adipose 11β‐HSD... ... hiện toàn bộ
Wiley - Tập 12 Số 1 - Trang 9-17 - 2004
Energy‐Dense Snack Food Intake in Adolescence: Longitudinal Relationship to Weight and FatnessAbstract Objective : The longitudinal relationship between the consumption of energy‐dense snack (EDS) foods and relative weight change during adolescence is uncertain. Using data from the Massachusetts Institute of Technology Growth and Development Study, the current analysis was undertaken to examine the longitudinal relationship of EDS f... ... hiện toàn bộ
Wiley - Tập 12 Số 3 - Trang 461-472 - 2004
Nghiên cứu Dược lý và Lâm sàng về Ephedrine và các Agonist Tạo Nhiệt Khác Dịch bởi AI Tóm tắt Trong nghiên cứu này, khi được sử dụng như một chất bổ sung cho chế độ ăn thấp năng lượng, tác nhân giao cảm ephedrine, kết hợp với các methylxanthine như caffeine, cải thiện khả năng giảm mỡ bằng hai cơ chế: ức chế sự thèm ăn trung ương và kích thích chi tiêu năng lượng ngoại biên thông qua quá trình oxy hóa mỡ. Sự giảm cân trung bình được ghi nhận là 16,6 ... ... hiện toàn bộ
Wiley - Tập 3 Số S4 - 1995
Obesity in Older Adults: Technical Review and Position Statement of the American Society for Nutrition and NAASO, The Obesity SocietyAbstract Obesity causes serious medical complications and impairs quality of life. Moreover, in older persons, obesity can exacerbate the age‐related decline in physical function and lead to frailty. However, appropriate treatment for obesity in older persons is controversial because of the reduction in relative health risks associated with increasing body mass inde... ... hiện toàn bộ
Wiley - Tập 13 Số 11 - Trang 1849-1863 - 2005
Obesity in the ElderlyAbstract In developed countries, there is a general increase in body weight and body mass index (BMI) with age, until ∼60 years of age, when body weight and BMI begin to decline. The proportion of intra‐abdominal fat, which is related to increased morbidity and mortality, progressively increases with age. There is also a progressive decline in energy intake and dail... ... hiện toàn bộ
Wiley - Tập 9 Số S11 - 2001
Bias, Discrimination, and ObesityAbstract This article reviews information on discriminatory attitudes and behaviors against obese individuals, integrates this to show whether systematic discrimination occurs and why, and discusses needed work in the field. Clear and consistent stigmatization, and in some cases discrimination, can be documented in three important areas of living: employment, educat... ... hiện toàn bộ
Wiley - Tập 9 Số 12 - Trang 788-805 - 2001
Resistin, Adiponectin, Ghrelin, Leptin, and Proinflammatory Cytokines: Relationships in ObesityAbstract Objective : To evaluate interactions among leptin, adiponectin, resistin, ghrelin, and proinflammatory cytokines [tumor necrosis factor receptors (TNFRs), interleukin‐6 (IL‐6)] in nonmorbid and morbid obesity.Research Methods and Procedures : We measured these hormones by immunoenzyme or r... ... hiện toàn bộ
Wiley - Tập 12 Số 6 - Trang 962-971 - 2004
Estradiol‐Induced Anorexia Is Independent of Leptin and Melanin‐Concentrating HormoneAbstract Objective : Treatment of male rodents with estradiol (E2 ) is associated with anorexia and weight loss by poorly understood mechanisms. We examined the role of the orexigenic hypothalamic peptide melanin‐concentrating hormone (MCH) and the appetite‐inhibiting, fat‐derived hormone leptin in mediating E2... ... hiện toàn bộ
Wiley - Tập 12 Số 4 - Trang 716-724 - 2004
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