VNU Journal of Science: Medical and Pharmaceutical Sciences
ACI
2615-9309
2588-1132
Việt Nam
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Cơ quản chủ quản: N/A
Lĩnh vực:
Các bài báo tiêu biểu
Preparation of Nano Niosomes Loaded with Rutin and Aloe Gel Extract
Tập 36 Số 1 - 2020
Rutin is a natural flavonoid that has many effects on human health and beauty. However, rutin has low solubility and bioavailability. Niosomes are drug delivery system that enhance drug permeation of drug through the skin. Aloe is widly used in cosmetic preparations due to its anti-aging, moisturizing and essential skin nutrients. Therefore, the aim of study is preparation of nano niosomes, loaded......
Simultaneous Quantification of Hederacoside C and α-hederin in Hedera Nepalensis K.Koch Using HPLC-UV
Tập 36 Số 3 - 2020
This study develops a high performance liquid chromatography with ultraviolet detection (HPLC-UV) for simultaneous quantification of hederacoside C and α-hederin in Hedera nepalensis K. Koch. The method proposed in this study was validated in terms of the analytical parameters such as high repeatability, high accuracy and good sensitivity. The method was used to determine the content of hede......
Development and Validation of a HPLC Method of Quantification of Caffeine and EGCG in Green Tea (Camellia sinensis L.) Extract
Tập 36 Số 3 - 2020
A simple high performance liquid chromatography (HPLC) with an isocratic eluent manner for quantification of caffeine and EGCG in green tea extract was established. The seperation system contained a C18-RP column (250 × 4.6 mm, 5 µm), a mobile phase of methanol/phosphoric acid/water (20/0.1/79.9, v/v) and a DAD detector at 280 nm. This validated method is convinient for rapid, routine analysis of ......
Evaluation of Antioxidant and α-glucosidase Inhibitory Activities of Codonopsisjavanica (Blume) Hook. f. Thoms’ Root Extract
Tập 36 Số 3 - 2020
This study aims to evaluate the antioxidant ability and α-glucosidase inhibitory activities of Codonopsisjavanica extract to elucidate its mechanism in the treatment of diabetes type 2. The roots of Codonopsisjavanica were extracted with ethanol solvents and fractionated with n-hexane, ethyl acetate and butanol solvents. The total extract and the fractions were evaluated for free radical scavengin......
Hepatoprotective Activities of Colocasia esculenta (L.) Schottin Mice Model with Liver Injury Induced by Paracetamol
Tập 36 Số 3 - 2020
This paper uses the model of experimental mouse liver damage with paracetamol to evaluate the liver protective effects of the methanol extract (Colocasia esculenta (L.) Schott) (MCE). After 8 days, the hepatoprotective activities of MCE in mice (damaged by paracetamol) at doses of 500, 1,000 and 2,000 mg/kg/day proved effective as the AST enzyme content decreased by 6.98, 22.84 and 26.59%, respect......
A Molecular Phylogeny of Panax L. Genus (Araliaceae) Based on ITS-rDNA and matK Support for Identification of Panax Species in Vietnam
Tập 36 Số 2 - 2020
Panax L. is a small genus in the Araliaceae family. In Vietnam, this genus is distributed in the high mountains in the North and in some high mountains in the Central Highlands. In traditional medicine, roots and rhizomes of all Panax species are of high utility. Recently, the finding of new distributions of some Panax species in Vietnam has caused much controversy and confusion. This study invest......
Cytotoxicity and Antioxidant Effects of Celastrus hindsii Benth. Leaf Extract
Tập 36 Số 1 - 2020
Celastrus hindsii Benth et Hook. is known as a herbal medicine for the treatment of cancer. In this study we evaluated the cytotoxic and antioxidant effects of Celastrus hindsii Benth et Hook. leaf extract. Samples of Celastrus hindsii were extracted with 90 % ethanol and subsequently fractionated with n-hexane, ethyl acetate (EtOAc) and n-butanol (n-BuOH) solvents. To evaluate the cytotoxic effec......
Associations of Single Nucleotide Polymorphism rs17782313 in Melanocortin 4 Receptor Gene with Anthropometric Indices in Normal and Obesity Primary School Children in Hanoi
Tập 34 Số 2 - 2018
Abstract: Melanocortin-4 receptor (MC4R) plays an important role in regulating food intake and energy balance. A number of studies have revealed that variant rs17782313 is significantly associated with obesity in different populations. However, its role to obesity in the Vietnamese populations has not been identified. This study aims to evaluate the association of rs17782313 with anthropometric in......
Đặc điểm lâm sàng, cận lâm sàng và kết quả điều trị hội chứng thận hư kháng thuốc steroid tại khoa Thận - Lọc máu, Bệnh viện Nhi Trung Ương
Tập 32 Số 1 - 2016
Tóm tắtMục tiêu nghiên cứu: Mô tả các đặc điểm lâm sàng, cận lâm sàng và kết quả điều trị của hội chứng thận hư tiên phát kháng thuốc steroid. Đối tượng nghiên cứu: 54 trẻ mắc HCTHTP kháng thuốc steroid nhập viện điều trị tại Khoa Thận-Lọc máu, bệnh viện Nhi Trung ương từ tháng 1 năm 2015 đến tháng 3 năm 2015. Phương pháp nghiên cứu: Mô tả tiến cứu. Kết quả: 31 bệnh nhân (57,4%) kháng thuốc sớm, ......
Evaluation of the In Vivo Bioavailability of Famotidine-loaded 3D-nano-cellulose Networks Produced by Acetobacter xylinum in Selected Culture Media
Tập 34 Số 2 - 2018
Abstract: 3D-nano-cellulose networks (3DNC) material has various applications in the biomedical fields and advanced drug delivery systems. 3DNC materials produced from Acetobacter xylinum in standard medium (3DNC-STM), coconut medium (3DNC-COM) and rice medium (3DNC-RIM) were loaded with famotidine by absorption method to obtain famotidine-containing 3DNC to investigate the in vivo bioavailabili......