VNU Journal of Science: Medical and Pharmaceutical Sciences
ACI
2615-9309
2588-1132
Việt Nam
Cơ quản chủ quản: N/A
Lĩnh vực:
Các bài báo tiêu biểu
Preparation of Nano Niosomes Loaded with Rutin and Aloe Gel Extract
Tập 36 Số 1 - 2020
Rutin is a natural flavonoid that has many effects on human health and beauty. However, rutin has low solubility and bioavailability. Niosomes are drug delivery system that enhance drug permeation of drug through the skin. Aloe is widly used in cosmetic preparations due to its anti-aging, moisturizing and essential skin nutrients. Therefore, the aim of study is preparation of nano niosomes, loaded...... hiện toàn bộ
Simultaneous Quantification of Hederacoside C and α-hederin in Hedera Nepalensis K.Koch Using HPLC-UV
Tập 36 Số 3 - 2020
This study develops a high performance liquid chromatography with ultraviolet detection (HPLC-UV) for simultaneous quantification of hederacoside C and α-hederin in Hedera nepalensis K. Koch. The method proposed in this study was validated in terms of the analytical parameters such as high repeatability, high accuracy and good sensitivity. The method was used to determine the content of hede...... hiện toàn bộ
Evaluation of Antioxidant and α-glucosidase Inhibitory Activities of Codonopsisjavanica (Blume) Hook. f. Thoms’ Root Extract
Tập 36 Số 3 - 2020
This study aims to evaluate the antioxidant ability and α-glucosidase inhibitory activities of Codonopsisjavanica extract to elucidate its mechanism in the treatment of diabetes type 2. The roots of Codonopsisjavanica were extracted with ethanol solvents and fractionated with n-hexane, ethyl acetate and butanol solvents. The total extract and the fractions were evaluated for free radical scavengin...... hiện toàn bộ
Development and Validation of a HPLC Method of Quantification of Caffeine and EGCG in Green Tea (Camellia sinensis L.) Extract
Tập 36 Số 3 - 2020
A simple high performance liquid chromatography (HPLC) with an isocratic eluent manner for quantification of caffeine and EGCG in green tea extract was established. The seperation system contained a C18-RP column (250 × 4.6 mm, 5 µm), a mobile phase of methanol/phosphoric acid/water (20/0.1/79.9, v/v) and a DAD detector at 280 nm. This validated method is convinient for rapid, routine analysis of ...... hiện toàn bộ
Hepatoprotective Activities of Colocasia esculenta (L.) Schottin Mice Model with Liver Injury Induced by Paracetamol
Tập 36 Số 3 - 2020
This paper uses the model of experimental mouse liver damage with paracetamol to evaluate the liver protective effects of the methanol extract (Colocasia esculenta (L.) Schott) (MCE). After 8 days, the hepatoprotective activities of MCE in mice (damaged by paracetamol) at doses of 500, 1,000 and 2,000 mg/kg/day proved effective as the AST enzyme content decreased by 6.98, 22.84 and 26.59%, respect...... hiện toàn bộ
Associations of Single Nucleotide Polymorphism rs17782313 in Melanocortin 4 Receptor Gene with Anthropometric Indices in Normal and Obesity Primary School Children in Hanoi
Tập 34 Số 2 - 2018
Abstract: Melanocortin-4 receptor (MC4R) plays an important role in regulating food intake and energy balance. A number of studies have revealed that variant rs17782313 is significantly associated with obesity in different populations. However, its role to obesity in the Vietnamese populations has not been identified. This study aims to evaluate the association of rs17782313 with anthropometric in...... hiện toàn bộ
A Molecular Phylogeny of Panax L. Genus (Araliaceae) Based on ITS-rDNA and matK Support for Identification of Panax Species in Vietnam
Tập 36 Số 2 - 2020
Panax L. is a small genus in the Araliaceae family. In Vietnam, this genus is distributed in the high mountains in the North and in some high mountains in the Central Highlands. In traditional medicine, roots and rhizomes of all Panax species are of high utility. Recently, the finding of new distributions of some Panax species in Vietnam has caused much controversy and confusion. This study invest...... hiện toàn bộ
Cytotoxicity and Antioxidant Effects of Celastrus hindsii Benth. Leaf Extract
Tập 36 Số 1 - 2020
Celastrus hindsii Benth et Hook. is known as a herbal medicine for the treatment of cancer. In this study we evaluated the cytotoxic and antioxidant effects of Celastrus hindsii Benth et Hook. leaf extract. Samples of Celastrus hindsii were extracted with 90 % ethanol and subsequently fractionated with n-hexane, ethyl acetate (EtOAc) and n-butanol (n-BuOH) solvents. To evaluate the cytotoxic effec...... hiện toàn bộ
The Application of Microfluidics in Preparing Nano Drug Delivery Systems
Tập 35 Số 1 - 2019
Microfluidics is an emerging and promising interdisciplinary technology which offers powerful platforms for precise production of novel functional materials (e.g., emulsion droplets, microcapsules, and nanoparticles as drug delivery vehicles) as well as high-throughput analyses (e.g., bioassays and diagnostics). Microfluidics has recently appeared as a new method of manufacturing nanostructures, w...... hiện toàn bộ
Screening Bioactive Compounds from Allium sativum as HER2 Inhibitors Targeting Breast Cancer by Docking Methods
Tập 37 Số 1 - 2021
This study aims to find the bioactive compounds from Allium sativum for inhibiting HER2 enzyme by using molecular docking method. In this study, the protein tyrosine kinase HER2 structure was obtained from Protein Data Bank; bioactive compounds were collected from previous publications on Allium sativum and were retrieved from PubChem database; molecular docking was done by Autodock vina software;...... hiện toàn bộ