VNU Journal of Science: Medical and Pharmaceutical Sciences

ACI

  2615-9309

  2588-1132

  Việt Nam

  nxupvWQAAAAJ

Cơ quản chủ quản:  N/A

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Các bài báo tiêu biểu

Cytotoxicity and Antioxidant Effects of Celastrus hindsii Benth. Leaf Extract
Tập 36 Số 1 - 2020
Bui Thanh Tung, Vu Manh Hung, Bui Thi Thanh Duyen
Celastrus hindsii Benth et Hook. is known as a herbal medicine for the treatment of cancer. In this study we evaluated the cytotoxic and antioxidant effects of Celastrus hindsii Benth et Hook. leaf extract. Samples of Celastrus hindsii were extracted with 90 % ethanol and subsequently fractionated with n-hexane, ethyl acetate (EtOAc) and n-butanol (n-BuOH) solvents. To evaluate the cytotoxic effec... hiện toàn bộ
Preparation of Nano Niosomes Loaded with Rutin and Aloe Gel Extract
Tập 36 Số 1 - 2020
Tran Thi Hai Yen, Hoang Thi Hien, Vu Thi Thu Giang
Rutin is a natural flavonoid that has many effects on human health and beauty. However, rutin has low solubility and bioavailability. Niosomes are drug delivery system that enhance drug permeation of drug through the skin. Aloe is widly used in cosmetic preparations due to its anti-aging, moisturizing and essential skin nutrients. Therefore, the aim of study is preparation of nano niosomes, loaded... hiện toàn bộ
Simultaneous Quantification of Hederacoside C and α-hederin in Hedera Nepalensis K.Koch Using HPLC-UV
Tập 36 Số 3 - 2020
Nguyen Tuan Hiep, Pham Thanh Huyen, Do Thi Thuy Linh, Hoang Thanh Duong, Nguyen Minh Khoi, Dinh Doan Long
 This study develops a high performance liquid chromatography with ultraviolet detection (HPLC-UV) for simultaneous quantification of hederacoside C and α-hederin in Hedera nepalensis K. Koch. The method proposed in this study was validated in terms of the analytical parameters such as high repeatability, high accuracy and good sensitivity. The method was used to determine the content of hederacos... hiện toàn bộ
The Application of Microfluidics in Preparing Nano Drug Delivery Systems
Tập 35 Số 1 - 2019
Tran Thi Hai Yen, Dang Thuy Linh, Pham Thi Minh Hue
Microfluidics is an emerging and promising interdisciplinary technology which offers powerful platforms for precise production of novel functional materials (e.g., emulsion droplets, microcapsules, and nanoparticles as drug delivery vehicles) as well as high-throughput analyses (e.g., bioassays and diagnostics). Microfluidics has recently appeared as a new method of manufacturing nanostructures, w... hiện toàn bộ
Evaluation of Antioxidant and α-glucosidase Inhibitory Activities of Codonopsisjavanica (Blume) Hook. f. Thoms’ Root Extract
Tập 36 Số 3 - 2020
Nguyen Thi Thanh Binh, Bui Thanh Tung, Ngo Ha Linh Trang, Nguyen Thi Thuy
This study aims to evaluate the antioxidant ability and α-glucosidase inhibitory activities of Codonopsisjavanica extract to elucidate its mechanism in the treatment of diabetes type 2. The roots of Codonopsisjavanica were extracted with ethanol solvents and fractionated with n-hexane, ethyl acetate and butanol solvents. The total extract and the fractions were evaluated for free radical scavengin... hiện toàn bộ
Hepatoprotective Activities of Colocasia esculenta (L.) Schottin Mice Model with Liver Injury Induced by Paracetamol
Tập 36 Số 3 - 2020
Le Thi Phuong Hoa, Tran Quoc Hung, Hoang Xuan Huy, Tran Quoc Viet, Phan Thi Mai Huong, Le Quy Thuong, Nguyen Quang Huy
This paper uses the model of experimental mouse liver damage with paracetamol to evaluate the liver protective effects of the methanol extract (Colocasia esculenta (L.) Schott) (MCE). After 8 days, the hepatoprotective activities of MCE in mice (damaged by paracetamol) at doses of 500, 1,000 and 2,000 mg/kg/day proved effective as the AST enzyme content decreased by 6.98, 22.84 and 26.59%, respect... hiện toàn bộ
Associations of Single Nucleotide Polymorphism rs17782313 in Melanocortin 4 Receptor Gene with Anthropometric Indices in Normal and Obesity Primary School Children in Hanoi
Tập 34 Số 2 - 2018
Tran Quang Binh, Le Thi Tuyet
Abstract: Melanocortin-4 receptor (MC4R) plays an important role in regulating food intake and energy balance. A number of studies have revealed that variant rs17782313 is significantly associated with obesity in different populations. However, its role to obesity in the Vietnamese populations has not been identified. This study aims to evaluate the association of rs17782313 with anthropometric in... hiện toàn bộ
A Molecular Phylogeny of Panax L. Genus (Araliaceae) Based on ITS-rDNA and matK Support for Identification of Panax Species in Vietnam
Tập 36 Số 2 - 2020
Phan Van Truong, Nguyen Minh Khoi, Dinh Doan Long, Pham Thanh Huyen, Nguyen Quynh Nga, Pham Thi Ngoc
Panax L. is a small genus in the Araliaceae family. In Vietnam, this genus is distributed in the high mountains in the North and in some high mountains in the Central Highlands. In traditional medicine, roots and rhizomes of all Panax species are of high utility. Recently, the finding of new distributions of some Panax species in Vietnam has caused much controversy and confusion. This study invest... hiện toàn bộ
Symptoms of Neonatal Pneumonia and Results of Its Treatment in Bac Ninh Obstetrics and Pediatrics Hospital
Tập 35 Số 1 - 2019
Nguyen Minh Hiep, Pham Trung Kien, Nguyen Nhu Truong, Vu Thi Phuong
This descriptive study describes clinical and subclinical symptoms of neonatal pneumonia and evaluates the results of its treatment in Bac Ninh Obstetrics and Pediatrics Hospital. In this study, 200 children diagnosed with neonatal pneumonia were treated in the hospital from May 1, 2018 to May 1, 2019. Among the patients, 57.0% were male; the male/female ratio was 1.33. There were 67/200 (33.5%) p... hiện toàn bộ
Thực trạng nhiễm khuẩn đường tiểu trên trẻ từ 2 tháng đến 5 tuổi có sốt tại khoa khám bệnh, Bệnh viện Nhi Trung ương
Tập 32 Số 2 - 2016
Lê Quang Phương, Phạm Văn Đếm, Nguyễn Thị Quỳnh Hương
Tóm tắtMục tiêu nghiên cứu: Tìm hiểu thực trạng nhiễm khuẩn đường tiểu trên trẻ từ 2 tháng đến 5 tuổi có sốt đến khám bệnh tại phòng khám bệnh viện Nhi Trung ương. Đối tượng nghiên cứu: 346 trẻ từ 2 tháng đến 5 tuổi có sốt đến khám tại khoa Khám bệnh, bệnh viện Nhi Trung ương trong thời gian từ 1/10/2015 đến 31/092016. Phương pháp nghiên cứu: Mô tả cắt ngang. Kết quả: Tỷ lệ NKĐT trên trẻ từ 2 thán... hiện toàn bộ