Induction of cytochrome P-450 related metabolic activities in the rat ventral prostateToxicology Letters - Tập 10 - Trang 61 - 1982
Toftgård Rune, Söderkvist Peter, Gustafsson Jan-Åke
Rats were treated with β-naphthoflavone (BNF) or phenobarbital (PB), 80 mg kg i.p. for 4 days and microsomes prepared from the ventral prostate were assayed for aryl hydrocarbon hydroxylase (AHH), 7-ethoxyresorufin-O-deethylase (7-EOD) and NADPH-cytochrome c reductase activities. The relative increase after BNF treatment was approx. 1000 times for AHH, and 800 times for 7-EOD, while the NADPH-cyto...... hiện toàn bộ