Association between liver fibrosis and thrombotic or bleeding events in acute coronary syndrome patientsThrombosis Journal -
Yupeng Liu, Jingjing Song, Wenyao Wang, Kuo Zhang, Jie Yang, Jun Wen, Xiaoxue Meng, Jun Gao, Jingjia Wang, Chunli Shao, Yi‐Da Tang
AbstractBackgroundThe prognostic implication of liver fibrosis in acute coronary
syndrome (ACS) patients are scarce. We sought to evaluate whether liver fibrosis
scores (LFS) were associated with thrombotic or bleeding events in patients with
acute coronary syndrome.MethodsWe included 6386 ACS patients who underwent
percutaneous coronary intervention (PCI). This study determined liver fibrosis
wit... hiện toàn bộ
New horizon in platelet function: with special reference to a recently-found molecule, CLEC-2Thrombosis Journal - Tập 14 - Trang 27-36 - 2016
Yukio Ozaki, Shogo Tamura, Katsue Suzuki-Inoue
Platelets play a key role in the pathophysiological processes of hemostasis and
thrombus formation. However, platelet functions beyond thrombosis and hemostasis
have been increasingly identified in recent years. A large body of evidence now
exists which suggests that platelets also play a key role in inflammation,
immunity, malignancy, and furthermore in organ development and regeneration,
such as... hiện toàn bộ
Plasma D-dimer concentration in patients with systemic sclerosisThrombosis Journal - Tập 4 - Trang 1-3 - 2006
Giuseppe Lippi, Alessandro Volpe, Paola Caramaschi, Gian Luca Salvagno, Martina Montagnana, Gian Cesare Guidi
Systemic sclerosis (SSc) is an autoimmune disorder of the connective tissue
characterized by widespread vascular lesions and fibrosis. Little is known so
far on the activation of the hemostatic and fibrinolytic systems in SSc, and
most preliminary evidences are discordant. To verify whether SSc patients might
display a prothrombotic condition, plasma D-dimer was assessed in 28 consecutive
SSc pati... hiện toàn bộ
Venous thromboembolism prevention post neck of femur fractures – does it make a difference?Thrombosis Journal - Tập 6 - Trang 1-3 - 2008
Radwane Faroug, Shireesha Konnuru, San S Min, Fazleenah Hussain, George Ampat
Neck of femur fractures predispose patients to venous thromboembolism (VTE).
NICE has issued guideline 46 to reduce this risk through the use of antithrombic
agents. We audited our department's VTE practise by reviewing the clinical notes
of 123 consecutive patients with no exclusions. We found our compliance to be a
low 6%. We also found that patients were likely to be given low molecular
heparin... hiện toàn bộ
Stroke in inflammatory bowel disease: a report of two cases and review of the literatureThrombosis Journal - Tập 6 - Trang 1-4 - 2008
Deepak Joshi, Tobias Dickel, Rakesh Aga, Gray Smith-Laing
Thrombosis is a recognised complication of inflammatory bowel disease (IBD), in
particular venous thrombosis. Arterial thrombosis, especially stroke is rare.
There is a paucity of information regarding stroke in IBD and its management.
The authors describe two cases of stroke in patients with IBD during periods of
increased disease activity. The literature regarding this devastating
complication a... hiện toàn bộ
Emergency correction of coagulation before major surgery in two elderly patients on oral anticoagulationThrombosis Journal - - 2007
Marzia Angelo, Bernd Gutmann, Michele Adami, Bernd Zagler, Anton Zelger, Christoph Pechlaner, Christian J. Wiedermann
Abstract Recommendations for urgent reversal of oral anticoagulation with
vitamin K1 antagonists are largely derived from case series employing empirical
dosing regimens with vitamin K1 and prothrombin complex concentrates. Data on
the use of prothrombin complex concentrates in this indication are scarce in the
elderly who are at high risk of both hemorrhagic and thrombotic complications.
The two ... hiện toàn bộ
Hemophilia A gene therapy via intraosseous delivery of factor VIII-lentiviral vectorsThrombosis Journal - Tập 14 - Trang 93-99 - 2016
Carol H. Miao
Current treatment of hemophilia A (HemA) patients with repeated infusions of
factor VIII (FVIII; abbreviated as F8 in constructs) is costly, inconvenient,
and incompletely effective. In addition, approximately 25 % of treated patients
develop anti-factor VIII immune responses. Gene therapy that can achieve
long-term phenotypic correction without the complication of anti-factor VIII
antibody format... hiện toàn bộ
Association of circulating proprotein convertase subtilisin/kexin type 9 concentration, prothrombin time and cardiovascular outcomes: a prospective cohort studyThrombosis Journal - Tập 19 - Trang 1-13 - 2021
Jia Peng, Ming-Ming Liu, Hui-Hui Liu, Yuan-Lin Guo, Na-Qiong Wu, Qian Dong, Jie Qian, Ke-Fei Dou, Cheng-Gang Zhu, Jian-Jun Li
Proprotein convertase subtilisin/kexin type 9 (PCSK9) is considered to have
multiple roles in the development of atherosclerosis, which is recently reported
to participate in the thrombotic process. We aimed to examine the relationship
between PCSK9 concentration, coagulation indexes and cardiovascular events. A
total of 2293 consecutive patients with angina-like chest pain and without
lipid-lower... hiện toàn bộ