Mechanisms of mesenchymal stem/stromal cell function Tập 7 Số 1 - 2016
Jeffrey L. Spees, Ryang Hwa Lee, Carl A. Gregory
AbstractThe past decade has seen an explosion of research directed toward better understanding of the mechanisms of mesenchymal stem/stromal cell (MSC) function during rescue and repair of injured organs and tissues. In addition to delineating cell–cell signaling and molecular controls for MSC differentiation, the field has made particular progress in defining seve...... hiện toàn bộ Mesenchymal stem cells generate a CD4+CD25+Foxp3+ regulatory T cell population during the differentiation process of Th1 and Th17 cells Tập 4 Số 3 - 2013
Patricia Luz‐Crawford, Mónica Kurte, Javiera Bravo-Alegría, Rafael Contreras‐Lopez, Estefanía Nova-Lamperti, Gautier Téjédor, Danièle Noël, Christian Jørgensen, Fernando Figueroa, Farida Djouad, Flavio Carrión
Treatment of severe COVID-19 with human umbilical cord mesenchymal stem cells - 2020
Lei Shu, Changming Niu, Ruyou Li, Tingrong Huang, Yan Wang, Mao Huang, Ningfei Ji, Zheng You, Xiaolin Chen, Lei Shi, Mingjing Wu, Kaili Deng, Jing Wei, Xueli Wang, Yang Cao, Jiaxin Yan, Ganzhu Feng
Abstract
Background
COVID-19 is a highly infectious respiratory disease. No therapeutics have yet been proven effective for treating severe COVID-19.
Objectives
To determine whether human umbilical cord mesenchymal stem cell infusion may be effective and safe for the ...... hiện toàn bộ Enhancement of therapeutic potential of mesenchymal stem cell-derived extracellular vesicles - 2019
Kyong-Su Park, Elga Bandeira, Ganesh Vilas Shelke, Cecilia Lässer, Jan Lötvall
Abstract
After the initial investigations into applications of mesenchymal stem cells (MSCs) for cell therapy, there was increased interest in their secreted soluble factors. Following studies of MSCs and their secreted factors, extracellular vesicles (EVs) released from MSCs have emerged as a new mode of intercellular crosstalk. MSC-derived EVs have ...... hiện toàn bộ Safety and neurological assessments after autologous transplantation of bone marrow mesenchymal stem cells in subjects with chronic spinal cord injury - 2014
Marcus Vinicius Mendonça, Ticiana Ferreira Larocca, Bruno Solano de Freitas Souza, Cristiane Flora Villarreal, Luiz Flávio Maia Silva, Ana Catarina Matos, Marco Antônio Caires Novaes, Cláudia Maria Pinheiro Bahia, Ana Carine de Oliveira Melo Martinez, Carla Martins Kaneto, Sissi Brandão Carneiro Furtado, Geraldo Pedral Sampaio, Ricardo Ribeiro dos Santos
Wnt and Notch signaling pathway involved in wound healing by targeting c-Myc and Hes1 separately Tập 6 Số 1
Yan Shi, Bin Shu, Ronghua Yang, Yingbin Xu, Bangrong Xing, Jian Liu, Lei Chen, Shaohai Qi, Xusheng Liu, Peng Wang, Jinming Tang, Xuejun Guo
Abstract
Introduction
Wnt and Notch signaling pathways are critically involved in relative cell fate decisions within the development of cutaneous tissues. Moreover, several studies identified the above two pathways as having a significant role during wound healing. However, their bi...... hiện toàn bộ