Recent advances on the 180-kDa epidermal antigen in autoimmune subepidermal bullous skin diseasesSpringer Seminars in Immunopathology - Tập 13 - Trang 401-412 - 1992
P. Bernard
The blistering skin disease bullous pemphigoid (BP) is an example of how autoantibodies from patients can be used as tools to improve our knowledge of the molecular structure of normal skin. BP autoantibodies bind to the basement membrane zone of normal human skin and usually react with two main epidermal antigens of approximately 230-kDa and 180-kDa. From recent studies, it is now established tha...... hiện toàn bộ
IgA nephropathySpringer Seminars in Immunopathology - Tập 9 - Trang 387-394 - 1987
Marie Christine Béné, Gilbert Faure
IgA nephropathy is a frequent disease, reported in almost every country in the world, which appears early in the life of males rather than females. It is readily diagnosed by immunofluorescence analysis of a renal biopsy. Its benign reputation begins to fade as more cases of rapid evolution towards renal failure are reported. Much has been learned about the various forms of IgAN in the past 15 yea...... hiện toàn bộ
Content and dynamics of the human antibody variable region repertoire to the Haemophilus influenzae type b polysaccharideSpringer Seminars in Immunopathology - Tập 15 - Trang 119-137 - 1993
Donald C. Reason, Alexander H. Lucas
Investigations into the immunobiology of Haemophilus infections were initiated with the goal of developing vaccines that would protect those at risk from disease. This goal has, for the most part, been achieved. The genetic basis of the anti-Hib PS antibody repertoire has been defined; most of the serum antibodies derive from two VH genes and seven VL genes. Some of the V region dynamics have been...... hiện toàn bộ
IntroductionSpringer Seminars in Immunopathology - Tập 21 - Trang 1-4 - 1999
Johan Grunewald, Hans Wigzell