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Impaired deformability of erythrocytes in diabetic rat and human: investigation by the nickel-mesh-filtration technique
Springer Science and Business Media LLC - Tập 25 - Trang 18-26 - 2011
Comprehensive research to quantify the deformability of erythrocytes in diabetic animals and humans has been lacking. The objective of this study was to compare the impairment of erythrocyte deformability in diabetic rats and patients by use of the same rheologic method. Deformability was investigated in streptozotocin-induced diabetic rats and diabetic patients, by using the highly sensitive and ......
Commentary on Shu Chien’s 2011 National Medal of Science Award: Buddha of a bioengineer
Springer Science and Business Media LLC - Tập 26 - Trang 1-2 - 2012
Construction and application a vane system in a rotational rheometer for determination of the rheological properties of Monascus ruber CCT 3802
Springer Science and Business Media LLC - Tập 24 - Trang 29-35 - 2010
The objectives of this work were the construction and adaptation of a vane system in a rotational rheometer; calibration of vane system using a mineral oil, and determination of rheological properties of the broth fermentation of Monascus ruber CCT 3802 at high cell density. Batch fermentation was carried out with glucose as the sole carbon source in a Bioflo III bioreactor. The consistency index ......
A computational model of the cerebrospinal fluid system incorporating lumped-parameter cranial compartment and one-dimensional distributed spinal compartment
Springer Science and Business Media LLC - Tập 25 - Trang 78-87 - 2011
The dynamic transmission of pressure through the cerebro-circulatory system may play a role in the genesis of pathological conditions of the brain and spinal cord. This study aims to lay down the foundations for computer modelling of the cerebrospinal (CSF) pressure dynamics in the cranio-spinal cavity as a single entity. The cerebro-vascular system was modelled as a set of resistors and capacitor......
Motion of polymerized albumin particles in a model arteriole in the presence of red blood cells
Springer Science and Business Media LLC - Tập 23 Số 1 - Trang 29-34 - 2009
Differentiation of stem/progenitor cells into vascular cells in response to fluid mechanical forces
Springer Science and Business Media LLC - Tập 24 - Trang 1-10 - 2010
Vascular functions are regulated not only by chemical mediators, such as hormones, cytokines, and neurotransmitters, but by mechanical hemodynamic forces generated by blood flow and blood pressure. The mechanical force-mediated regulation is based on the ability of vascular cells, including endothelial cells and smooth muscle cells, to recognize fluid mechanical forces, i.e., the shear stress prod......
Direct evidence of the vasodilator action of carbon dioxide on subcutaneous microvasculature in rats by use of intra-vital video-microscopy
Springer Science and Business Media LLC - Tập 24 - Trang 42-46 - 2010
The therapeutic effects of carbon dioxide (CO2) on cutaneous tissue blood flow in the human have long been well recognized. Although CO2 has vasodilator action, in-vivo evidence of its action on the microcirculation of the skin, and of its mechanism, has rarely been reported. We studied the direct effects of CO2 on in-vivo microvasculature and blood flow rate by using an intra-vital video-microsco......
Rheological properties of agar microgel suspensions prepared using water-in-oil emulsions
Springer Science and Business Media LLC - Tập 24 - Trang 70-76 - 2011
Agar microgel suspensions containing sugar fatty acid esters were prepared using a water-in-oil (w/o) emulsion system. The volume fraction of microgel particles was adjusted by centrifugation to obtain high volume fraction suspensions. The relationship between the apparent equilibrium shear modulus and the volume fraction was analyzed using a hard-sphere model. The rigidity of the microgel particl......
Slowness of blood flow and resultant thrombus formation in cerebral aneurysms
Springer Science and Business Media LLC - Tập 24 - Trang 47-55 - 2011
It is not yet fully understood what causes cerebral aneurysms to rupture. Although no definitive conclusion has been reached, it is considered that there are haemodynamic, biochemical and physiological factors contributing to rupture. Numerical techniques seem promising for investigation of this multi-physical phenomenon. In fact, recent intensive numerical studies with computational fluid dynamic......
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