It is not yet fully understood what causes cerebral aneurysms to rupture.
Although no definitive conclusion has been reached, it is considered that there
are haemodynamic, biochemical and physiological factors contributing to rupture.
Numerical techniques seem promising for investigation of this multi-physical
phenomenon. In fact, recent intensive numerical studies with computational fluid
dynamic... hiện toàn bộ
A two-dimensional (2D) numerical simulation of convective–diffusive transport of
LDL in the artery wall, coupled with the wall shear stress gradient
(WSSG)-dependent LDL consumption of smooth muscle cells (SMCs) is presented.
SMCs are modeled as an array of solid cylindrical pillars embedded in a
continuous porous media which represents the interstitial proteoglycan and
collagen fiber matrix. The ... hiện toàn bộ
A markedly reduced blood flow, an elevation of hematocrit and an increased
aggregability of erythrocytes [red blood cells (RBCs)] are risk factors for
venous thrombus formation (intravascular blood coagulation). However, these risk
factors alone seem to be insufficient to stimulate the coagulation cascade in
the absence of a primary triggering mechanism. In this paper, our rheological
and biochemi... hiện toàn bộ