Springer Science and Business Media LLC
SCIE-ISI SCOPUS (2004-2023)
1897-4287
Cơ quản chủ quản: BMC , BioMed Central Ltd.
Lĩnh vực:
Genetics (clinical)Oncology
Các bài báo tiêu biểu
Germline deletions in the EPCAM gene as a cause of Lynch syndrome – literature review
Tập 11 Số 1 - 2013
Hereditary breast cancer: ever more pieces to the polygenic puzzleAbstract
Several susceptibility genes differentially impact on the lifetime risk for breast cancer. Technological advances over the past years have enabled the detection of genetic risk factors through high-throughput screening of large breast cancer case–control series. High- to intermediate penetrance alleles have now been identified in more than 20 gen... ... hiện toàn bộ
Tập 11 Số 1 - 2013
CDKN2A germline alterations and the relevance of genotype-phenotype associations in cancer predispositionAbstract AlthoughCDKN2A is well-known as a susceptibility gene for melanoma and pancreatic cancer, germline variants have also been anecdotally associated with a broader range of neoplasms including neural system tumors, head and neck squamous cell carcinomas, breast carcinomas, as well as sarcomas. TheCDKN2A gene ... ... hiện toàn bộ
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Familial gastric cancer: detection of a hereditary cause helps to understand its etiologyAbstract
Worldwide, gastric cancer is one of the most common forms of cancer, with a high morbidity and mortality. Several environmental factors predispose to the development of gastric cancer, such as Helicobacter pylori infection, diet and smoking. Familial clustering of gastric cancer is seen in 10% of cases, and approximatel... ... hiện toàn bộ
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