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DNA and RNA analyses in detection of genetic predisposition to cancer
Springer Science and Business Media LLC - Tập 6 - Trang 1-8 - 2008
Joanna Matyjasik, Bartłomiej Masojć, Grzegorz Kurzawski
Genome wide association identified colorectal cancer susceptibility loci and colorectal cancer risk in Lynch syndrome
Springer Science and Business Media LLC - Tập 8 - Trang 1-1 - 2010
Mala Pande, Marsha L Frazier, Patrick M Lynch, Russell Broaddus, Christopher I Amos
Deciding the operation type according to mismatch repair status among hereditary nonpolyposis colorectal cancer patients: should a tailored approach be applied, or does one size fit all?
Springer Science and Business Media LLC - Tập 19 - Trang 1-12 - 2021
Chun-Kai Liao, Yueh-Chen Lin, Yu-Jen Hsu, Yih-Jong Chern, Jeng-Fu You, Jy-Ming Chiang
Although extended colectomy (EC) was recommended for HNPCC patients, previous studies did not show significantly improved overall survival. Immunohistochemical (IHC) stain of mismatch repair (MMR) gene protein expression is now a feasible and reliable test clinically. Therefore, we tried to investigate whether we could use MMR IHC stain to select operation types in HNPCC patients. Between 1995 and...... hiện toàn bộ
Cytotoxic and targeted therapy for hereditary cancers
Springer Science and Business Media LLC - - 2016
Aglaya G. Iyevleva, Evgeny N. Imyanitov
Serum concentrations of Cu, Se, Fe and Zn in patients diagnosed with pancreatic cancer
Springer Science and Business Media LLC - Tập 13 - Trang 1-2 - 2015
Marcin Lener, Anna Wiechowska-Kozlowska, Rodney J Scott, Magdalena Muszynska, Jozef Kladny, Piotr Waloszczyk, Anna Rutkowska, Grzegorz Sukiennicki, Tomasz Gromowski, Katarzyna Jaworska-Bieniek, Thierry van de Wetering, Katarzyna Kaczmarek, Anna Jakubowska, Jan Lubinski
Improving the provision of Melbourne Health Familial Cancer services to Victoria’s Culturally and Linguistically Diverse (CALD) communities
Springer Science and Business Media LLC - - 2012
Yasmin Bylstra, Maira Kentwell, GJ Lindeman, Ingrid Winship, L Hodgkin
Clinical and genetic aspects of testicular germ cell tumours
Springer Science and Business Media LLC - Tập 6 - Trang 1-12 - 2008
Martijn F. Lutke Holzik, Rolf H. Sijmons, Josette E.H.M. Hoekstra-Weebers, Dirk T. Sleijfer, Harald J. Hoekstra
In this paper we review clinical and genetic aspects of testicular germ cell tumours (TGCTs). TGCT is the most common type of malignant disorder in men aged 15-40 years. Its incidence has increased sharply in recent years. Fortunately, survival of patients with TGCT has improved enormously, which can chiefly be attributed to the cisplatin-based polychemotherapy that was introduced in the nineteen ...... hiện toàn bộ
Colorectal adenomas and cancer link to chromosome 13q22.1-13q31.3 in a large family with excess colorectal cancer
Springer Science and Business Media LLC - Tập 8 - Trang 1-1 - 2010
Deborah W Neklason, Therese M Tuohy, Jeffery Stevens, Brith Otterud, Lisa Baird, Richard A Kerber, Wade S Samowitz, Scott K Kuwada, Mark F Leppert, Randall W Burt
A genome-wide association study to identify genetic markers associated with endometrial cancer grade
Springer Science and Business Media LLC - Tập 10 - Trang 1-1 - 2012
T O’Mara, D Duffy, DJ Thompson, S Ahmed, K Ferguson, CS Healey, G Montgomery, M Shah, J Morrison, PP Pharoah, AM Dunning, PM Webb, DF Easton, AB Spurdle
MYH Gene Status in Polish FAP Patients without APC Gene Mutations
Springer Science and Business Media LLC - Tập 4 - Trang 1-5 - 2006
Marzena Skrzypczak, Marta Podralska, Wolfram Heinritz, Ursula G Froster, Daniel Lipiński, Ryszard Słomski, Andrzej Pławski
Familial Adenomatous Polyposis (FAP) is an inheritable predisposition for the occurrence of numerous polyps in the large intestine. In about 50% of all patients, the occurrence of the disease is conditioned by heterozygotic mutations of the APC gene. Screening for genetic factors in persons without mutations in the APC gene led to the identification of homozygotic mutations of the MYH gene as the ...... hiện toàn bộ
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