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Genome wide association identified colorectal cancer susceptibility loci and colorectal cancer risk in Lynch syndrome
Springer Science and Business Media LLC - Tập 8 - Trang 1-1 - 2010
Mala Pande, Marsha L Frazier, Patrick M Lynch, Russell Broaddus, Christopher I Amos
Mismatch repair gene mutations and cancer risks: an update
Springer Science and Business Media LLC - Tập 10 - Trang 1-1 - 2012
AK Win, JL Hopper, MA Jenkins
Systemic therapy for hereditary cancer
Springer Science and Business Media LLC - Tập 10 - Trang 1-1 - 2012
Evgeny N Imyanitov
The effect of neoadjuvant platinum-based chemotherapy in BRCA mutated triple negative breast cancers -systematic review and meta-analysis
Springer Science and Business Media LLC - Tập 17 - Trang 1-10 - 2019
Olga Caramelo, Cristina Silva, Francisco Caramelo, Cristina Frutuoso, Teresa Almeida-Santos
Triple negative breast cancers (TNBC) are associated with an aggressive clinical course, earlier recurrence and short survival. BRCA – mutated tumours represent up to 25% of all TNBC. BRCA status is being studied as a predictive biomarker of response to platinum agents. However, the predictive role of BRCA status is still uncertain in this setting. Since TNBC is a very heterogeneous group of disea...... hiện toàn bộ
Large serrated polyps: molecular and familial links to a serrated neoplasia predisposition
Springer Science and Business Media LLC - Tập 8 - Trang 1-1 - 2010
Matthew F Kalady, Kathryn DeJulius, Anna Bennett, James M Church
The NOD2 3020insC Mutation in Women with Breast Cancer from the Bydgoszcz Region in Poland. First Results
Springer Science and Business Media LLC - Tập 4 - Trang 1-5 - 2006
Hanna Janiszewska, Olga Haus, Anna Lauda-Świeciak, Aneta Bąk, Tomasz Mierzwa, Jan Sir, Ryszard Laskowski
The frameshift NOD2 gene mutation 3020insC is predominantly associated with Crohn's disease, but predisposes to many types of common cancers as well. We studied the frequency of this mutant NOD2 allele in 148 breast cancer women from the Bydgoszcz region in Poland. The NOD2 mutation was present in 8.8% of the patients. The mean age at breast cancer diagnosis of the mutation carriers was 43 years. ...... hiện toàn bộ
Folic acid and breast cancer risk
Springer Science and Business Media LLC - Tập 10 - Trang 1-2 - 2012
Katarzyna Durda, Katrzyna Jaworska-Bieniek, Krzysztof Kąklewski, Jan Lubiński, Anna Jakubowska
Cancer risk in MLH1, MSH2 and MSH6 mutation carriers; different risk profiles may influence clinical management
Springer Science and Business Media LLC - Tập 7 - Trang 1-7 - 2009
Dewkoemar Ramsoekh, Anja Wagner, Monique E van Leerdam, Dennis Dooijes, Carli MJ Tops, Ewout W Steyerberg, Ernst J Kuipers
Lynch syndrome (LS) is associated with a high risk for colorectal cancer (CRC) and extracolonic malignancies, such as endometrial carcinoma (EC). The risk is dependent of the affected mismatch repair gene. The aim of the present study was to calculate the cumulative risk of LS related cancers in proven MLH1, MSH2 and MSH6 mutation carriers. The studypopulation consisted out of 67 proven LS familie...... hiện toàn bộ
Iron and breast cancer risk
Springer Science and Business Media LLC - Tập 10 - Trang 1-2 - 2012
Grzegorz Sukiennicki, Magdalena Muszyńska, Tomasz Huzarski, Jacek Gronwald, Cezary Cybulski, Tadeusz Dębniak, Aleksandra Tołoczko-Grabarek, Oleg Oszurek, Anna Jakubowska, Antoni Morawski, Jan Lubiński
Pathological diagnosis of ovarian cancer
Springer Science and Business Media LLC - - 2012
Hilda High, Michael Friedlander
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