Artificially designed pathogens – a diagnostic option for future military deploymentsSpringer Science and Business Media LLC - Tập 2 - Trang 1-5 - 2015
Andreas E. Zautner, Wycliffe O. Masanta, Rebecca Hinz, Ralf Matthias Hagen, Hagen Frickmann
Diagnostic microbial isolates of bio-safety levels 3 and 4 are difficult to handle in medical field camps under military deployment settings. International transport of such isolates is challenging due to restrictions by the International Air Transport Association. An alternative option might be inactivation and sequencing of the pathogen at the deployment site with subsequent sequence-based revit...... hiện toàn bộ
Cardiac-targeted PIASy gene silencing mediates deSUMOylation of caveolin-3 and prevents ischemia/reperfusion-induced Nav1.5 downregulation and ventricular arrhythmiasSpringer Science and Business Media LLC -
Chen-chen Hu, Xin Wei, Jinmin Liu, Linlin Han, Chengkun Xia, Jing Wu, Tao You, Afang Zhu, Shanglong Yao, Shiying Yuan, Haodong Xu, Zhengyuan Xia, Tingting Wang, Weike Mao
Abstract
Background
Abnormal myocardial Nav1.5 expression and function cause lethal ventricular arrhythmias during myocardial ischemia–reperfusion (I/R). Protein inhibitor of activated STAT Y (PIASy)-mediated caveolin-3 (Cav-3) SUMO modification affects Cav-3 binding to the volt...... hiện toàn bộ
Development of rapid advice guideline and standard and continuous updating guideline: experiences and practiceSpringer Science and Business Media LLC - Tập 8 - Trang 1-3 - 2021
Ying-Hui Jin, Xiao-Mei Yao, Xian-Tao Zeng
We published rapid advice guidelines and updated guidelines for coronavirus disease 2019 (COVID-19) management on February 6, 2020, and September 4, 2020, respectively. These two guidelines vary widely in their developmental background, type of evidence, grade of recommendation and so on. We shared our experience for the development of these two guidelines to help clinical practitioners better und...... hiện toàn bộ
Small molecules facilitate single factor-mediated sweat gland cell reprogrammingSpringer Science and Business Media LLC - - 2022
Ji, Shuai-Fei, Zhou, Lai-Xian, Sun, Zhi-Feng, Xiang, Jiang-Bing, Cui, Shao-Yuan, Li, Yan, Chen, Hua-Ting, Liu, Yi-Qiong, Gao, Huan-Huan, Fu, Xiao-Bing, Sun, Xiao-Yan
Large skin defects severely disrupt the overall skin structure and can irreversibly damage sweat glands (SG), thus impairing the skin’s physiological function. This study aims to develop a stepwise reprogramming strategy to convert fibroblasts into SG lineages, which may provide a promising method to obtain desirable cell types for the functional repair and regeneration of damaged skin. The expres...... hiện toàn bộ
Surveillance for respiratory infectious diseases caused by 6 common viruses in a recruit training site in the Northern region of ChinaSpringer Science and Business Media LLC - Tập 4 - Trang 1-7 - 2017
Wei-Wei Chen, Wen Xu, Yang-Xin Xie, Yun-Hui Zhang, Dan Wu, Fu-Sheng Wang, Min Zhao
Recruit training sites are places with a high incidence of respiratory infectious diseases. Effective surveillance for acute respiratory infectious diseases in a recruit training site is an important way to prevent disease outbreaks. Eight hundred recruits (722 males and 78 females) enlisted in autumn 2015 received a background survey within 24 h of settlement at the recruit training site, includi...... hiện toàn bộ