Adipokine Effects on BoneSpringer Science and Business Media LLC - Tập 7 - Trang 240-248 - 2009
Ian R. Reid, J. B. Richards
The adipocyte is an important source of factors that act as circulating regulators of bone metabolism. These include estrogens, and the adipokines, leptin, resistin, adiponectin, and probably others. Leptin acts directly on bone cells, and in some experimental models these effects are modified by its actions on the central nervous system, which impact on appetite, body weight, and insulin sensitiv...... hiện toàn bộ
Genetic Causes of Kidney Stones and Kidney FailureSpringer Science and Business Media LLC - Tập 10 - Trang 2-18 - 2011
Lada Beara-Lasic, Vidar O. Edvardsson, Runolfur Palsson, John C. Lieske, David S. Goldfarb, Dawn S. Milliner
Genetics plays an important role in establishing susceptibility to nephrolithiasis, although diet and other environmental factors make major contributions. In a small number of patients, the genetic causes of stones are more clearly established. Four of these hereditary diseases include primary hyperoxaluria, Dent disease, cystinuria, and adenine phosphoribosyltransferase deficiency, which results...... hiện toàn bộ
Bone Disease and Idiopathic HypercalciuriaSpringer Science and Business Media LLC - Tập 6 - Trang 82-94 - 2008
Joseph E. Zerwekh
There is sufficient epidemiological and clinical data demonstrating an association between reduced bone mineral density and idiopathic hypercalciuria (IH). There have been relatively few studies that have addressed the underlying defect in bone remodeling. The limited studies to date suggest that increased bone turnover occurs in some forms of IH such as fasting hypercalciuria or renal calcium lea...... hiện toàn bộ
Glucocorticoid-Induced Osteoporosis and the New ACR GuidelineSpringer Science and Business Media LLC - Tập 15 - Trang 123-127 - 2017
Robert A. Adler
Glucocorticoid-induced osteoporosis (GIOP) continues to be the most common cause of secondary osteoporosis because at any time about 1% of the adult population has been prescribed oral glucocorticoids. Surprisingly, there are relatively few treatment studies of GIOP, particularly of younger individuals including women of child bearing potential and children. Thus, recommendations for management of...... hiện toàn bộ
Hyperparathyroidism nguyên phát Dịch bởi AI Springer Science and Business Media LLC - Tập 1 - Trang 25-34 - 2002
John P. Bilezikian, Shonni J. Silverberg
Những mô tả lâm sàng sớm nhất về hyperparathyroidism nguyên phát chỉ ra rằng đây là một rối loạn tiến triển không thể tránh khỏi. Hiện tại, ở những cá nhân không có triệu chứng và không đáp ứng các hướng dẫn phẫu thuật, hyperparathyroidism nguyên phát, nhìn chung, không có vẻ gì là sẽ tiến triển. Các bệnh nhân không có triệu chứng có xu hướng giữ nguyên trạng thái không triệu chứng trong nhiều năm...... hiện toàn bộ
#hyperparathyroidism nguyên phát #sỏi thận #mật độ xương #nồng độ canxi huyết thanh #bài tiết canxi qua nước tiểu
Evidence-based practices for safe patient handling and movementSpringer Science and Business Media LLC - Tập 4 Số 1 - Trang 55-69 - 2006
Nelson, Audrey, Baptiste, Andrea S.
Efforts to reduce injuries associated with patient handling are often based on tradition and personal experience rather than scientific evidence. The purpose of this article is to summarize current evidence for interventions designed to reduce caregiver injuries, a significant problem for decades. Despite strong evidence, published over three decades, the most commonly used strategies have demonst...... hiện toàn bộ
Role of Osteoblasts in Regulation of Energy MetabolismSpringer Science and Business Media LLC - Tập 11 - Trang 2-10 - 2012
Barbara C. Silva, Stavroula Kousteni
Diseases of compromised glucose metabolism, such as type II diabetes, have been for years correlated with defects in bone mass or strength. However, a reverse regulation of energy homeostasis by the skeleton was not suspected until very recently. A series of genetic studies have demonstrated that the skeleton regulates glucose metabolism and energy expenditure in an endocrine manner. The bone-deri...... hiện toàn bộ
IntroductionSpringer Science and Business Media LLC - Tập 1 - Trang 93-94 - 2002
Henry G. Bone