Cardiovascular Development and Angiogenesis in the Early Vertebrate EmbryoSpringer Science and Business Media LLC - Tập 4 - Trang 234-245 - 2013
Warren W. Burggren
Embryonic cardiovascular physiology (as opposed to that of the more developed fetus) is being more closely examined by developmental physiologists to explore the onset of cardiovascular function and its regulation, as opposed to the later maturation of these processes as is typically examined in fetal mammal models. As our understanding of embryonic physiology grows, the dogma that the early embry...... hiện toàn bộ
Speckle-Tracking Echocardiography Enables Model-Based Identification of Regional Stiffness Indices in the Left Ventricular MyocardiumSpringer Science and Business Media LLC - Tập 11 - Trang 176-187 - 2020
William M. Torres, Francis G. Spinale, Tarek Shazly
Left ventricular (LV) remodeling is a critical process underlying heart failure (HF) development and progression. While LV global longitudinal strain determined by speckle-tracking echocardiography (STE) provides a promising basis to monitor LV remodeling, reported strain measures are limited by the masking of regional differences and a dependency on hemodynamic load. Our goal is to extend two-dim...... hiện toàn bộ
Experimental and Mouse-Specific Computational Models of the Fbln4SMKO Mouse to Identify Potential Biomarkers for Ascending Thoracic Aortic AneurysmSpringer Science and Business Media LLC - Tập 13 - Trang 558-572 - 2022
Marisa S. Bazzi, Ramin Balouchzadeh, Shawn N. Pavey, James D. Quirk, Hiromi Yanagisawa, Vijay Vedula, Jessica E. Wagenseil, Victor H. Barocas
To use computational methods to explore geometric, mechanical, and fluidic biomarkers that could correlate with mouse lifespan in the Fbln4SMKO mouse. Mouse lifespan was used as a surrogate for risk of a severe cardiovascular event in cases of ascending thoracic aortic aneurysm. Image-based, mouse-specific fluid-structure-interaction models were developed for Fbln4SMKO mice (n = 10) at ages two an...... hiện toàn bộ
Patient-Specific Quantitative In-Vivo Assessment of Human Mitral Valve Leaflet Strain Before and After MitraClip RepairSpringer Science and Business Media LLC - Tập 14 - Trang 677-693 - 2023
Natalie T. Simonian, Hao Liu, Sneha Vakamudi, Mark J. Pirwitz, Alison M. Pouch, Joseph H. Gorman, Robert C. Gorman, Michael S. Sacks
Mitral regurgitation (MR) is a highly prevalent and deadly cardiac disease characterized by improper mitral valve (MV) leaflet coaptation. Among the plethora of available treatment strategies, the MitraClip is an especially safe option, but optimizing its long-term efficacy remains an urgent challenge. We applied our noninvasive image-based strain computation pipeline [1] to intraoperative transes...... hiện toàn bộ
Hemodynamic Effects of Additional Pulmonary Blood Flow on Glenn and Fontan CirculationSpringer Science and Business Media LLC - Tập 11 - Trang 268-282 - 2020
Xiangyu Chen, Haiyun Yuan, Jiawei Liu, Neichuan Zhang, Chengbin Zhou, Meiping Huang, Qifei Jian, Jian Zhuang
Additional pulmonary blood flow (APBF) can provide better pulsating blood flow and systemic arterial oxygen saturation, while low blood pulsation and low oxygen saturation are defects of the Fontan and Glenn procedure. Studying the hemodynamic effect of APBF is beneficial for clinical decisions. This study aimed to explore the effect on particle washout, as well as the differences among the sensit...... hiện toàn bộ
The Fluid-Dynamics of Endo Vascular Aneurysm Sealing (EVAS) System failureSpringer Science and Business Media LLC - Tập 12 - Trang 300-310 - 2021
F. Battista, R. Ficarelli, A. Perrotta, P. Gualtieri, C. M. Casciola, G. P. Romano, M. Taurino
The main objective of this work is to investigate hemodynamics phenomena occurring in EVAS (Endo Vascular Aneurysm Sealing), to understand if and how they could lead to type 1a endoleaks and following re-intervention. To this aim, methods based on computational fluid mechanics are implemented as a tool for checking the behavior of a specific EVAS configuration, starting from the post-operative con...... hiện toàn bộ
Residual Stress Estimates from Multi-cut Opening Angles of the Left VentricleSpringer Science and Business Media LLC - Tập 11 Số 4 - Trang 381-393 - 2020
Xin Zhuan, Xiaoyu Luo
Abstract
Purpose
Residual stress tensor has an essential influence on the mechanical behaviour of soft tissues and can be particularly useful in evaluating growth and remodelling of the heart and arteries. It is currently unclear if one single radial cut using the opening angle method can accurately estimate the residual stress. I...... hiện toàn bộ