Patient-Specific Quantitative In-Vivo Assessment of Human Mitral Valve Leaflet Strain Before and After MitraClip RepairSpringer Science and Business Media LLC - Tập 14 - Trang 677-693 - 2023
Natalie T. Simonian, Hao Liu, Sneha Vakamudi, Mark J. Pirwitz, Alison M. Pouch, Joseph H. Gorman, Robert C. Gorman, Michael S. Sacks
Mitral regurgitation (MR) is a highly prevalent and deadly cardiac disease characterized by improper mitral valve (MV) leaflet coaptation. Among the plethora of available treatment strategies, the MitraClip is an especially safe option, but optimizing its long-term efficacy remains an urgent challenge. We applied our noninvasive image-based strain computation pipeline [1] to intraoperative transes...... hiện toàn bộ
Effect of Pneumatic Tubing System Transport on Platelet Apheresis UnitsSpringer Science and Business Media LLC - Tập 9 - Trang 515-527 - 2018
Jevgenia Zilberman-Rudenko, Frank Z. Zhao, Stephanie E. Reitsma, Annachiara Mitrugno, Jiaqing Pang, Joseph J. Shatzel, Beth Rick, Christina Tyrrell, Wohaib Hasan, Owen J. T. McCarty, Martin A. Schreiber
Platelet apheresis units are transfused into patients to mitigate or prevent bleeding. In a hospital, platelet apheresis units are transported from the transfusion service to the healthcare teams via two methods: a pneumatic tubing system (PTS) or ambulatory transport. Whether PTS transport affects the activity and utility of platelet apheresis units is unclear. We quantified the gravitational for...... hiện toàn bộ
PediaFlow™ Maglev Ventricular Assist Device: A Prescriptive Design ApproachSpringer Science and Business Media LLC - Tập 1 - Trang 104-121 - 2010
James F. Antaki, Michael R. Ricci, Josiah E. Verkaik, Shaun T. Snyder, Timothy M. Maul, Jeongho Kim, Dave B. Paden, Marina V. Kameneva, Bradley E. Paden, Peter D. Wearden, Harvey S. Borovetz
This report describes a multi-disciplinary program to develop a pediatric blood pump, motivated by the critical need to treat infants and young children with congenital and acquired heart diseases. The unique challenges of this patient population require a device with exceptional biocompatibility, miniaturized for implantation up to 6 months. This program implemented a collaborative, prescriptive ...... hiện toàn bộ
Towards the Identification of Hemodynamic Parameters Involved in Arteriovenous Fistula Maturation and Failure: A ReviewSpringer Science and Business Media LLC - - 2017
Marco Franzoni, Michael T. Walsh
Native arteriovenous fistulas have a high failure rate mainly due to the lack of maturation and uncontrolled neo-intimal hyperplasia development. Newly established hemodynamics is thought to be central in driving the fistula fate, after surgical creation. To investigate the effects of realistic wall shear stress stimuli on endothelial cells, an in vitro approach is necessary in order to reduce the...... hiện toàn bộ
The Transitional Cardiac Pumping Mechanics in the Embryonic HeartSpringer Science and Business Media LLC - Tập 4 - Trang 246-255 - 2013
Brennan M. Johnson, Deborah M. Garrity, Lakshmi Prasad Dasi
Several studies have linked abnormal blood flow dynamics to the formation of congenital heart defects during the early stages of development. The objective of this study is to document the transition of pumping mechanics from the early tube stage to the late looping stage of the embryonic heart. The optically transparent zebrafish embryonic heart was utilized as the in vivo model and was studied u...... hiện toàn bộ
Development of Inspired Therapeutics Pediatric VAD: Benchtop Evaluation of Impeller Performance and Torques for MagLev Motor DesignSpringer Science and Business Media LLC - - 2022
Landon H Tompkins, Steven R Prina, Barry Gellman, Gino Morello, Thomas J. Roussel, Jonathan A. Kopechek, Stuart J. Williams, Priscilla C Petit, Mark S. Slaughter, Steven C. Koenig, Kurt A. Dasse
Long-Term Venovenous Connection for Extracorporeal Carbon Dioxide Removal (ECCO2R)–Numerical Investigation of the Connection to the Common Iliac VeinsSpringer Science and Business Media LLC - Tập 11 - Trang 362-380 - 2020
N. B. Steuer, K. Hugenroth, T. Beck, J. Spillner, R. Kopp, S. Reinartz, T. Schmitz-Rode, U. Steinseifer, G. Wagner, J. Arens
Currently used cannulae for extracorporeal carbon dioxide removal (ECCO2R) are associated with complications such as thrombosis and distal limb ischemia, especially for long-term use. We hypothesize that the risk of these complications is reducible by attaching hemodynamically optimized grafts to the patient’s vessels. In this study, as a first step towards a long-term stable ECCO2R connection, we...... hiện toàn bộ