Speckle-Tracking Echocardiography Enables Model-Based Identification of Regional Stiffness Indices in the Left Ventricular MyocardiumSpringer Science and Business Media LLC - Tập 11 - Trang 176-187 - 2020
William M. Torres, Francis G. Spinale, Tarek Shazly
Left ventricular (LV) remodeling is a critical process underlying heart failure (HF) development and progression. While LV global longitudinal strain determined by speckle-tracking echocardiography (STE) provides a promising basis to monitor LV remodeling, reported strain measures are limited by the masking of regional differences and a dependency on hemodynamic load. Our goal is to extend two-dim...... hiện toàn bộ
Patient-Specific Quantitative In-Vivo Assessment of Human Mitral Valve Leaflet Strain Before and After MitraClip RepairSpringer Science and Business Media LLC - Tập 14 - Trang 677-693 - 2023
Natalie T. Simonian, Hao Liu, Sneha Vakamudi, Mark J. Pirwitz, Alison M. Pouch, Joseph H. Gorman, Robert C. Gorman, Michael S. Sacks
Mitral regurgitation (MR) is a highly prevalent and deadly cardiac disease characterized by improper mitral valve (MV) leaflet coaptation. Among the plethora of available treatment strategies, the MitraClip is an especially safe option, but optimizing its long-term efficacy remains an urgent challenge. We applied our noninvasive image-based strain computation pipeline [1] to intraoperative transes...... hiện toàn bộ
Hemodynamic Effects of Additional Pulmonary Blood Flow on Glenn and Fontan CirculationSpringer Science and Business Media LLC - Tập 11 - Trang 268-282 - 2020
Xiangyu Chen, Haiyun Yuan, Jiawei Liu, Neichuan Zhang, Chengbin Zhou, Meiping Huang, Qifei Jian, Jian Zhuang
Additional pulmonary blood flow (APBF) can provide better pulsating blood flow and systemic arterial oxygen saturation, while low blood pulsation and low oxygen saturation are defects of the Fontan and Glenn procedure. Studying the hemodynamic effect of APBF is beneficial for clinical decisions. This study aimed to explore the effect on particle washout, as well as the differences among the sensit...... hiện toàn bộ
Effect of Pneumatic Tubing System Transport on Platelet Apheresis UnitsSpringer Science and Business Media LLC - Tập 9 - Trang 515-527 - 2018
Jevgenia Zilberman-Rudenko, Frank Z. Zhao, Stephanie E. Reitsma, Annachiara Mitrugno, Jiaqing Pang, Joseph J. Shatzel, Beth Rick, Christina Tyrrell, Wohaib Hasan, Owen J. T. McCarty, Martin A. Schreiber
Platelet apheresis units are transfused into patients to mitigate or prevent bleeding. In a hospital, platelet apheresis units are transported from the transfusion service to the healthcare teams via two methods: a pneumatic tubing system (PTS) or ambulatory transport. Whether PTS transport affects the activity and utility of platelet apheresis units is unclear. We quantified the gravitational for...... hiện toàn bộ
PediaFlow™ Maglev Ventricular Assist Device: A Prescriptive Design ApproachSpringer Science and Business Media LLC - Tập 1 - Trang 104-121 - 2010
James F. Antaki, Michael R. Ricci, Josiah E. Verkaik, Shaun T. Snyder, Timothy M. Maul, Jeongho Kim, Dave B. Paden, Marina V. Kameneva, Bradley E. Paden, Peter D. Wearden, Harvey S. Borovetz
This report describes a multi-disciplinary program to develop a pediatric blood pump, motivated by the critical need to treat infants and young children with congenital and acquired heart diseases. The unique challenges of this patient population require a device with exceptional biocompatibility, miniaturized for implantation up to 6 months. This program implemented a collaborative, prescriptive ...... hiện toàn bộ
Towards the Identification of Hemodynamic Parameters Involved in Arteriovenous Fistula Maturation and Failure: A ReviewSpringer Science and Business Media LLC - - 2017
Marco Franzoni, Michael T. Walsh
Native arteriovenous fistulas have a high failure rate mainly due to the lack of maturation and uncontrolled neo-intimal hyperplasia development. Newly established hemodynamics is thought to be central in driving the fistula fate, after surgical creation. To investigate the effects of realistic wall shear stress stimuli on endothelial cells, an in vitro approach is necessary in order to reduce the...... hiện toàn bộ