Identification and expression of adenosine deaminases acting on tRNA (ADAT) during early tail regeneration of the earthwormSpringer Science and Business Media LLC - Tập 43 - Trang 295-301 - 2021
Yoo Bin Yoon, Sung-Jin Cho, Soon Cheol Park
RNA editing is a widespread phenomenon in all metazoans. One of the common RNA editing event is the chemical conversion of adenosine to inosine (A-to-I) catalyzed by adenosine deaminases acting on tRNA (ADAT). During D. melanogaster development, the ADAT1 transcript was found to localize mainly to the central nervous system including brain and ventral nerve cord during brain development. Although ...... hiện toàn bộ
Genetic diversity and structure analyses on the natural populations of diploids and triploids of tiger lily, Lilium lancifolium Thunb., from Korea, China, and JapanSpringer Science and Business Media LLC - Tập 38 - Trang 467-477 - 2016
Sung-Il Lee, Xuan Truong Nguyen, Jong-Hwa Kim, Nam-Soo Kim
Tiger lily, Lilium lancifolium Thumb. is an endemic species in Korea. Genetic structure and diversity of diploid and triploid tiger lily accessions were analyzed using SSRP and IRAP molecular markers. All genetic indices analyzed showed that the diploids hold higher genetic variations compared to the triploids which were collected from Korea, China, and Japan. All variations found in triploids wer...... hiện toàn bộ
Deciphering genome-wide WRKY gene family of Triticum aestivum L. and their functional role in response to Abiotic stressSpringer Science and Business Media LLC - Tập 41 - Trang 79-94 - 2018
Saurabh Gupta, Vinod Kumar Mishra, Sunita Kumari, Raavi, Ramesh Chand, Pritish Kumar Varadwaj
WRKY transcription factors (TFs) act in regulating plant growth and development as well as in response to different stress. Some earlier studies done by individual researchers reported different wheat WRKY TFs. Although, the recently released wheat genome has opened an avenue to investigate wheat WRKYs (TaWRKY) TFs. Prime objective of this study to performed genome-wide classifications of TaWRKYs ...... hiện toàn bộ
Will family studies return to prominence in human genetics and genomics? Rare variants and linkage analysis of complex traitsSpringer Science and Business Media LLC - Tập 33 - Trang 1-8 - 2011
Donald W. Bowden
A major focus of modern human genetics has been the search for genetic variations that contribute to human disease. These studies originated in families and used linkage methods as a primary analytical tool. With continued technical improvements, these family-based linkage studies have been very powerful in identifying genes contributing to monogenic disorders. When these methods were applied to d...... hiện toàn bộ
Single-nucleus RNA sequencing reveals cell type-specific transcriptome alterations of Down syndrome hippocampus using the Dp16 mouse modelSpringer Science and Business Media LLC - Tập 45 - Trang 1305-1315 - 2023
Zuolin Zhou, Chunchun Zhi, Die Chen, Zhaowei Cai, Xiaoling Jiang
Down syndrome (DS), the most frequently occurring human chromosomal disorder, is caused by trisomy 21. The exact molecular effects of trisomy on certain cell populations in the brain remain poorly understood. The purpose of this study was to investigate the effects of trisomy on the transcriptomes of various types of neurons and nonneuronal cells in the hippocampus. A total of 8993 nuclei from the...... hiện toàn bộ
Association analysis of the SNP (rs345476947) in the FUT2 gene with the production and reproductive traits in pigsSpringer Science and Business Media LLC - Tập 40 - Trang 199-206 - 2017
Haifei Wang, Sen Wu, Jiayun Wu, Shouyong Sun, Shenglong Wu, Wenbin Bao
The FUT2 gene was considered as an important candidate for pathogenic infections, while the potential associations between this gene and the production and reproductive traits of pigs have not been explored. In this study, we detected the genetic variants of porcine FUT2 gene and analyzed the associations of the polymorphisms with FUT2 mRNA expression and production and reproductive traits (age at...... hiện toàn bộ
Hypoxia-induced PLOD2 regulates invasion and epithelial-mesenchymal transition in endometrial carcinoma cellsSpringer Science and Business Media LLC - Tập 42 - Trang 317-324 - 2019
Junhui Wan, Junli Qin, Qinyue Cao, Ping Hu, Chunmei Zhong, Chunhua Tu
Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 (PLOD2) was induced in hypoxia and participated in cancer development. However, the role of PLOD2 in endometrial carcinoma remains unclear. To explore the influences and regulation mechanism of PLOD2 in endometrial carcinoma under hypoxic condition. The small interfering RNA (siRNA) targeting to PLOD2 and pcDNA3.1-PLPD2 were transfected to endomet...... hiện toàn bộ