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Protective effect of Neorhodomela aculeata methanolic extract through the suppressive action on NF-κB and STAT pathway in IL-1β and IFN-γ induced β-cell damage
Springer Science and Business Media LLC - Tập 32 - Trang 239-246 - 2010
Seo Kyoung Park, Kang-Beom Kwon, Do-Gon Ryu, Jung-Soo Han, Han Gil Choi
The protective effects of Neorhodomela aculeata methanolic extract (N. aculeata) on IL-1β and IFN-γ induced β-cell cytotoxicity were examined in a rat insulinoma (RIN) cell line and islets. In the cytokine-treated RIN cells, nitric oxide (NO) production was reduced about 94% at 50 μg/ml of N. aculeata and its suppressive effect was ten times greater as compared to other effective oriental herbs, s...... hiện toàn bộ
Superior single nucleotide polymorphisms that contribute to two main routes of the fatty acid synthesis pathway in Korean cattle
Springer Science and Business Media LLC - Tập 40 Số 9 - Trang 945-954 - 2018
Jea-Young Lee, Jae Jung Ha, Junkoo Yi, Ji Eun Jang, Wooseok Lee, Young‐Sun Lee, Do Hoon Oh, Kyudong Han
Prediction of gene expression and codon usage in human parasitic helminths
Springer Science and Business Media LLC - Tập 39 Số 1 - Trang 27-36 - 2017
Gulshana A. Mazumder, Arif Uddin, Supriyo Chakraborty
Comparative transcriptome analysis of differentially expressed genes between the curly and normal leaves of Cymbidium goeringii var. longibracteatum
Springer Science and Business Media LLC - Tập 38 - Trang 985-998 - 2016
Huijuan Ning, Chao Zhang, Jianxin Fu, Yirong Fan
Normal and the spontaneous spirally rolled leaves of Cymbidium goeringii var. longibracteatum were used for RNA sequencing analyses using the Illumina paired-end sequencing technique to figure out the differently-expressed genes in two samples. About 5.65 and 4.82 Gb sequencing data of raw reads were obtained from 2 cDNA libraries of normal and the spirally rolled leaves respectively. After data f...... hiện toàn bộ
Biểu hiện gen huyết sắc tố đặc hiệu theo mô cho thấy sự thích nghi với điều kiện biển địa phương ở cá đục Bắc Hải (Platichthys flesus L.) Dịch bởi AI
Springer Science and Business Media LLC - Tập 35 - Trang 541-547 - 2013
Peter Foged Larsen, Einar Eg Nielsen, Michael Møller Hansen, Tobias Wang, Kristian Meier, Cino Pertoldi, Volker Loeschcke
Các phân tích di truyền gần đây về các gen ứng cử viên và biểu hiện gen trong các loài cá biển đã cung cấp bằng chứng cho sự thích nghi địa phương nhằm đối phó với sự khác biệt môi trường, bất chấp việc thiếu tín hiệu mạnh về cấu trúc quần thể từ các dấu hiệu di truyền trung lập thông thường. Trong nghiên cứu này, biểu hiện của các gen chuỗi alpha và beta của huyết sắc tố đã được nghiên cứu ở cá đ...... hiện toàn bộ
#thích nghi địa phương #cá biển #biểu hiện gen #huyết sắc tố #độ mặn
Analysis of genetic diversity and relationships among waxy maize inbred lines in Korea using SSR markers
Springer Science and Business Media LLC - - 2010
Kyu Jin, Jong Yeol Park, Ki Jin Park, Ju Kyong Lee
Porcine insulin-like growth factor 1 (IGF1) gene polymorphisms are associated with body size variation
Springer Science and Business Media LLC - Tập 35 - Trang 523-528 - 2013
Pengxia Niu, Sang-Wook Kim, Bong-Hwan Choi, Tae-Hun Kim, Jong-Joo Kim, Kwan-Suk Kim
Previous studies have confirmed that insulin growth factor-1 (IGF1) plays important roles in growth and body size in humans and animals. However, whether single nucleotide polymorphisms (SNPs) within the IGF1 gene affects body size and growth in pigs has been unclear. We identified IGF1 SNPs among 5 pig breeds (Berkshire, Duroc, Landrace, Yorkshire and Korea Native Pig) and found that the G allele...... hiện toàn bộ
Guanine nucleotide-binding protein 2, GNBP2, accelerates the progression of clear cell renal cell carcinoma via regulation of STAT3 signaling transduction pathway
Springer Science and Business Media LLC - Tập 45 - Trang 1-11 - 2022
Qingfei Cao, Jiaji Ma, Weitao Li, Peng Hong, Tong Shen, Ming Tong
Guanine nucleotide-binding protein 2 (GNBP2) is a GTPase that has critical roles in host immunity and some types of cancer, but its function in clear cell renal cell carcinoma (ccRCC) is not fully understood. This work explored the role of GNBP2 in ccRCC progression and the underlying molecular mechanism. Two public human cancer databases TNMplot and TISIDB were employed to analyze the expression ...... hiện toàn bộ
Investigation of Hanwoo-specific structural variations using whole-genome sequencing data
Springer Science and Business Media LLC - Tập 41 - Trang 233-240 - 2018
Jangho Park, Wonseok Shin, Seyoung Mun, Man Hwan Oh, Dajeong Lim, Dong-Yep Oh, Youngjune Bhak, Jong Bhak, Yong-Soo Park, Kyudong Han
The total length of the cattle genome is approximately ~ 3 billion base pairs. About half of the bovine genome (46.5%) is composed of transposable elements (TEs). The TEs could be a major source of genomic structural variations (SVs) between cattle breeds. These SVs have led to genomic fluidity and rearrangements between interspecies. TE-mediated insertion and deletion events could have a strong i...... hiện toàn bộ
Salivary amylase gene (AMY1) copy number variation has only a minor correlation with body composition in Chinese adults
Springer Science and Business Media LLC - Tập 45 - Trang 935-943 - 2023
Xinming Zhang, Colin Moran, Ruiyuan Wang, Yue Zhou, Naomi Brooks
According to the WHO, about 39% of the global adult population were overweight or obese in 2016. Obesity has high heritability, with more than 1000 variants so far identified. There have been reports indicating that salivary amylase gene (AMY1) copy number was one of these variants, yet its association with obesity remains controversial. Our research aimed to provide more evidence on the relations...... hiện toàn bộ
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