Endogenous enkephalin does not contribute to the cerebral anti-hyperalgesic action of gabapentinSpringer Science and Business Media LLC - Tập 53 - Trang 1428-1432 - 2010
ShaoHui Chen, Jing Zhao, YuGuang Huang, AiLun Luo, PingPing Zuo, Nan Yang, WenYu Hao
The aim of this study was to investigate the role of endogenous enkephalin in the cerebral antihyperalgesic action of gabapentin. Neuropathic pain models and antihyperalgesic effect of gabapentin were confirmed by the presentation and changes of mechanical allodynia and thermal hyperalgesia of operated mouse hind paws. The results suggested that endogenous enkephalin may not be involved in the ant...... hiện toàn bộ
Sustained local delivery of insulin for potential improvement of peri-implant bone formation in diabetesSpringer Science and Business Media LLC - Tập 55 - Trang 948-957 - 2012
Yong Han, XueYan Zhang, E LingLing, DongSheng Wang, HongChen Liu
Dental implantation is an effective standard treatment modality to restore missing teeth and maxillofacial defects. However, in diabetics there is an increased risk for implant failure due to impaired peri-implant osseous healing. Early topical insulin treatment was recently shown to normalize diabetic bone healing by rectifying impairments in osteoblastic activities. In this study, insulin/poly(l...... hiện toàn bộ
DICER1 mutations in twelve Chinese patients with pleuropulmonary blastomaSpringer Science and Business Media LLC - Tập 60 - Trang 714-720 - 2017
Siyu Cai, Xisi Wang, Wen Zhao, Libing Fu, Xiaoli Ma, Xiaoxia Peng
Our aim is to examine the impact of DICER1 mutations on the pathogenesis of pleuropulmonary blastoma (PPB) by evaluating the mutation frequency and investigating the family history of Chinese patients with PPB. The family histories of 12 children with PPB recruited consecutively were surveyed. Blood samples from patients and their first-degree relatives were tested for DICER1 mutations. Whole-geno...... hiện toàn bộ
High glucose levels impact visual response properties of retinal ganglion cells in C57 mice—An in vitro physiological studySpringer Science and Business Media LLC - Tập 60 - Trang 1428-1435 - 2017
Yuan Zhou, Chunxia Xiao, Mingliang Pu
This study investigated visual response properties of retinal ganglion cells (RGCs) under high glucose levels. Extracellular single-unit responses of RGCs from mouse retinas were recorded. And the eyecup was prepared as a flat mount in a recording chamber and superfused with Ames medium. The averaged RF size of the ON RGCs (34.1±2.9, n=14) was significantly smaller than the OFF RGCs under the HG (...... hiện toàn bộ
Spatio-temporal changes in biomass carbon sinks in China’s forests from 1977 to 2008Springer Science and Business Media LLC - Tập 56 - Trang 661-671 - 2013
ZhaoDi Guo, HuiFeng Hu, Pin Li, NuYun Li, JingYun Fang
Forests play a leading role in regional and global carbon (C) cycles. Detailed assessment of the temporal and spatial changes in C sinks/sources of China’s forests is critical to the estimation of the national C budget and can help to constitute sustainable forest management policies for climate change. In this study, we explored the spatio-temporal changes in forest biomass C stocks in China betw...... hiện toàn bộ