Ethyl glucuronide in hair of non-excessive alcohol consumers: correlations and gender influenceSpringer Science and Business Media LLC - Tập 34 - Trang 186-190 - 2015
Cleo L. Crunelle, Delphine Cappelle, Eva Flamand, Jeroen Cox, Adrian Covaci, Mireille De Doncker, Alexander L. N. van Nuijs, Peter Michielsen, Michel Yegles, Hugo Neels
Hair ethyl glucuronide (hEtG) is a marker used for previous alcohol consumption. Correlations have been reported between the amount of alcohol consumed and hEtG concentration, but little has been published regarding relatively low levels of alcohol consumption and associated hEtG concentrations close to the limit of quantification (LOQ). Here, we investigate hEtG concentrations in non-excessive (<...... hiện toàn bộ
VOCs as fingerprints for the chemical profiling of hashish samples analyzed by HS-SPME/GC–MS and multivariate statistical toolsSpringer Science and Business Media LLC - Tập 36 - Trang 243-260 - 2017
Roberta Ascrizzi, Guido Flamini, Mario Giusiani, Fabio Stefanelli, Viviana Deriu, Silvio Chericoni
The statistical evaluation of the chemical profile of seized hashish samples is a valuable tool to aid the estimation of the route through which the material has reached the dealers’ market. In this study, the complete volatile organic compound (VOC) emission profiles of 48 seized hashish samples have been analyzed by means of headspace solid-phase microextraction/gas chromatography–mass spectrome...... hiện toàn bộ
Heroin poisoning deaths with 6-acetylmorphine in blood: demographics of the victims, previous drug-related offences, polydrug use, and free morphine concentrations in femoral bloodSpringer Science and Business Media LLC - Tập 30 - Trang 19-24 - 2011
Alan Wayne Jones, Anita Holmgren, Johan Ahlner
This article discusses cases of drug-poisoning death in which 6-acetylmorphine (6-AM) was identified in blood as evidence for recent use of heroin. We report the demographics of the victims, previous drug-related offences, polydrug use, and the concentrations of free morphine in peripheral blood. After solid-phase extraction, morphine, codeine, and 6-AM were determined in blood samples by isotope-...... hiện toàn bộ
Organ distribution of 4-MEC, MDPV, methoxetamine and α-PVP: comparison of QuEChERS and SPESpringer Science and Business Media LLC - Tập 36 - Trang 320-333 - 2018
Sabrina Lehmann, Bastian Schulze, Andreas Thomas, Thomas Kamphausen, Mario Thevis, Markus A. Rothschild, Katja Mercer-Chalmers-Bender
An organ distribution investigation was carried out on two deceased (A and B) who consumed 4-methylethcathinone (4-MEC), methylenedioxypyrovalerone (MDPV), methoxetamine (MXE) and α-pyrrolidinopentiophenone (α-PVP). The detection of the aforementioned drugs in the specimens was performed on a liquid chromatography–tandem mass spectrometry system. Two different extraction methods were compared with...... hiện toàn bộ
Postmortem detection of rocuronium and sugammadex by LC/MS in the blood of a patient who died on postoperative day 8Springer Science and Business Media LLC - Tập 37 - Trang 250-253 - 2018
Yoshiaki Iwamuro, Takaya Murakami, Reiko Ishimaru, Satoshi Chinaka
This case report describes the purposeful forensic detection of both the muscle relaxant rocuronium and the reversal agent sugammadex in the blood of a patient who died 8 days after surgery. The two compounds were analyzed by liquid chromatography/mass spectrometry (LC/MS). The molar concentrations of the two compounds were almost the same, indicating that rocuronium had lost its muscle relaxant e...... hiện toàn bộ