Ichthyosiform Pityriasis Rubra Pilaris-Like Eruption Secondary to Ponatinib Therapy: Case Report and Literature ReviewSpringer Science and Business Media LLC - Tập 4 - Trang 1-4 - 2017
Ariel E. Eber, Alyx Rosen, Kate E. Oberlin, Alessio Giubellino, Paolo Romanelli
Tyrosine kinase inhibitors have revolutionized the chemotherapy arena as targeted therapies for a multitude of malignancies. They are more selective than conventional chemotherapy, and often elicit fewer systemic adverse events, however toxicities still exist. Cutaneous toxicities are common and their management presents a novel challenge to physicians and patients. Ponatinib is a third-generation...... hiện toàn bộ
A Suspected Case of Silodosin-Induced ErythrodermaSpringer Science and Business Media LLC - Tập 2 - Trang 1-4 - 2015
Annie Liu, Lyne Giroux
An 86-year-old man developed a suspected severe erythroderma during treatment with silodosin (dosage unknown) for benign prostatic enlargement. Two weeks after starting silodosin, he developed a total-body scaling dermatitis. A biopsy was planned but the patient improved at his subsequent visit and it was not taken. Silodosin was discontinued and the patient received UVB phototherapy, clobetasol o...... hiện toàn bộ
Curling of Hair in Two Female Patients Taking AlitretinoinSpringer Science and Business Media LLC - Tập 5 - Trang 1-4 - 2018
Kim Alting, Florence van Hunsel
Two female patients aged 45 and 51 years experienced curling of hair during treatment with alitretinoin (Toctino®). For one patient, the indication for use was severe chronic hand eczema, but for the second patient the indication was not reported. After 5 and 9 months, respectively, the patients developed hair texture changes and their straight hair began to curl. The dose of alitretinoin was redu...... hiện toàn bộ
Hazardous Drug Diversion of Valproate from a General Practitioner to his Patient’s DogSpringer Science and Business Media LLC - Tập 4 - Trang 1-4 - 2017
Pierre-Marie Morice, Joachim Alexandre, Alexandre Cesbron, Marion Sassier, Sophie Fedrizzi, Xavier Humbert
General practitioners are key stakeholders in good prescribing practices. More than half of patients have at least one unintended medication discrepancy upon hospital admission, some of which have the potential to cause severe discomfort or clinical deterioration. We report a case of a drug mistakenly administered to a 66-year-old man with cirrhosis and chronic alcoholism. Based on his regular pre...... hiện toàn bộ
Rifampicin-Induced Fever in a Patient with Brucellosis: A Case ReportSpringer Science and Business Media LLC - Tập 5 - Trang 1-4 - 2018
Mesut Yilmaz, Canan Yasar, Selda Aydin, Okan Derin, Bahadir Ceylan, Ali Mert
We present a 35-year-old female patient who was started on rifampicin (900 mg orally once daily) and trimethoprim/sulfamethoxazole (TMP/SMX) (160/800 mg orally twice daily) after being diagnosed with brucellosis. Following defervescence and improvement in her general condition, fever recurred on the 12th day of treatment. A re-challenge drug test lead to causality assessment and treatment was swit...... hiện toàn bộ
Hypersensitivity Eosinophilic Myocarditis in a Patient Receiving Multiple Drug Therapy: Challenges in Diagnosis and Defining the AetiologySpringer Science and Business Media LLC - Tập 3 - Trang 1-4 - 2016
Dario Gulin, Jozica Sikic, Jasna Cerkez Habek, Sandra Jerkovic Gulin, Edvard Galic
Eosinophilic myocarditis (EM) is a rare and potentially fatal disease if left untreated. Because the disease can have a delayed presentation and can appear even after 2 years, its underlying causes often remain unknown. We report the case of a 63-year-old man with an atypical clinical presentation of hypersensitive EM and significant coronary artery disease, which was confirmed through coronary an...... hiện toàn bộ
A Case of Interstitial Lung Disease Probably Related to Rituximab TreatmentSpringer Science and Business Media LLC - Tập 2 - Trang 1-4 - 2015
Massimo Calderazzo, Pierandrea Rende, Paolo Gambardella, Giovambattista De Sarro, Luca Gallelli
A 44-year-old male developed interstitial lung disease (ILD) during treatment with rituximab (375 mg/m2 weekly intravenous × 4 weeks) for the management of immune thrombocytopenia (ITP). After 1 month of treatment he developed dyspnea, fever (38.9 °C), an increase of C-reactive protein (CRP) and white blood cells with hypoxemia, and decreased platelets. Chest X-ray and high-resolution computed tom...... hiện toàn bộ
Confusion between Two Amphotericin B Formulations Leading to a Paediatric RehospitalisationSpringer Science and Business Media LLC - Tập 3 - Trang 1-6 - 2016
Mapi Fleury, Caroline Fonzo-Christe, Charline Normand, Pascal Bonnabry
A heavily immunosuppressed, 43-kg, 9-year-old patient was recovering from a bone marrow transplant. Primary prophylaxis against invasive fungal infections was liposomal amphotericin B (AmBisome®, 2.3 mg/kg [100 mg] two times per week). Once home, following a first amphotericin B infusion, he presented with strong diarrhoea and vomiting; this was repeated after the second infusion. The clinical sit...... hiện toàn bộ