Springer Science and Business Media LLC
Công bố khoa học tiêu biểu
* Dữ liệu chỉ mang tính chất tham khảo
Sắp xếp:
Integrated management of cardiac failure: the cardiac failure clinic
Springer Science and Business Media LLC - Tập 5 - Trang 20-25 - 2011
The prevalence of the risk factors and the risk of cardiac failure are both increasing in China. This might be the consequence of the changes of the life conditions (emigration to the urban areas, changes in the diet and life style, lack of physical exercise, etc.). The wide range of clinical presentations of cardiac failure (acute or chronic) and of therapeutic approaches (medical or surgical) ma...... hiện toàn bộ
Cyclospora cayetanensis infections among diarrheal outpatients in Shanghai: a retrospective case study
Springer Science and Business Media LLC - Tập 12 - Trang 98-103 - 2018
Cyclospora cayetanensis is a foodborne and waterborne pathogen that causes endemic and epidemic human diarrhea worldwide. A few epidemiological studies regarding C. cayetanensis infections in China have been conducted. During 2013, a total of 291 stool specimens were collected from patients with diarrhea at a hospital in urban Shanghai. C. cayetanensis was not detected in any of the stool specimen...... hiện toàn bộ
Single-cell RNA-seq data analysis on the receptor ACE2 expression reveals the potential risk of different human organs vulnerable to 2019-nCoV infection
Springer Science and Business Media LLC - Tập 14 - Trang 185-192 - 2020
It has been known that, the novel coronavirus, 2019-nCoV, which is considered similar to SARS-CoV, invades human cells via the receptor angiotensin converting enzyme II (ACE2). Moreover, lung cells that have ACE2 expression may be the main target cells during 2019-nCoV infection. However, some patients also exhibit non-respiratory symptoms, such as kidney failure, implying that 2019-nCoV could als...... hiện toàn bộ
Platelet membrane-based and tumor-associated platelettargeted drug delivery systems for cancer therapy
Springer Science and Business Media LLC - Tập 12 - Trang 667-677 - 2018
Platelets have long been known to play critical roles in hemostasis by clumping and clotting blood vessel injuries. Recent experimental evidence strongly indicates that platelets can also interact with tumor cells by direct binding or secreting cytokines. For example, platelets have been shown to protect circulating cancer cells in blood circulation and to promote tumor metastasis. In-depth unders...... hiện toàn bộ
Tissue engineering of cartilage, tendon and bone
Springer Science and Business Media LLC - Tập 5 - Trang 61-69 - 2011
Tissue engineering aims to produce a functional tissue replacement to repair defects. Tissue reconstruction is an essential step toward the clinical application of engineered tissues. Significant progress has recently been achieved in this field. In our laboratory, we focus on construction of cartilage, tendon and bone. The purpose of this review was to summarize the advances in the engineering of...... hiện toàn bộ
Clinical data quality problems and countermeasure for real world study
Springer Science and Business Media LLC - - 2014
Advances in COVID-19: the virus, the pathogenesis, and evidence-based control and therapeutic strategies
Springer Science and Business Media LLC - Tập 14 - Trang 117-125 - 2020
Since the outbreak of the COVID-19 pandemic in early December 2019, 81 174 confirmed cases and 3242 deaths have been reported in China as of March 19, 2020. The Chinese people and government have contributed huge efforts to combat this disease, resulting in significant improvement of the situation, with 58 new cases (34 were imported cases) and 11 new deaths reported on March 19, 2020. However, as...... hiện toàn bộ
Research progress in pathogenic genes of hereditary non-syndromic mid-frequency deafness
Springer Science and Business Media LLC - Tập 10 - Trang 137-142 - 2016
Hearing impairment is considered as the most prevalent impairment worldwide. Almost 600 million people in the world suffer from mild or moderate hearing impairment, an estimated 10% of the human population. Genetic factors play an important role in the pathogenesis of this disorder. Hereditary hearing loss is divided into syndromic hearing loss (associated with other anomalies) and non-syndromic h...... hiện toàn bộ
Reproductive toxicity study with a novel deoxyguanosine analogue (Metacavir) in pregnant SD rats
Springer Science and Business Media LLC - Tập 9 - Trang 82-89 - 2014
Our preliminary studies demonstrated that Metacavir has potential to become a new anti-HBV agent. The main targets of the toxic effects of Metacavir, in rhesus monkeys, were gastrointestinal tracts, liver, blood, and kidneys, which were not related to mitochondrial effects. In this study, the maternal toxicity, embryo-fetal developmental toxicity and teratogenicity were studied in pregnant Sprague...... hiện toàn bộ
The regulatory sciences for stem cell-based medicinal products
Springer Science and Business Media LLC - Tập 8 - Trang 190-200 - 2014
Over the past few years, several new achievements have been made from stem cell studies, many of which have moved up from preclinical stages to early, or from early to middle or late, stages thanks to relatively safe profile and preliminary evidence of effectiveness. Moreover, some stem cell-based products have been approved for marketing by different national regulatory authorities. However, many...... hiện toàn bộ
Tổng số: 613
- 1
- 2
- 3
- 4
- 5
- 6
- 10