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Tác động lâu dài của các loại chất ức chế 3-hydroxy-3-methylglutaryl coenzyme A reductase đối với sự thay đổi tốc độ lọc cầu thận tại Hàn Quốc Dịch bởi AI
Springer Science and Business Media LLC - Tập 13 - Trang 713-722 - 2018
Seo Yeon Baik, Hyunah Kim, So Jung Yang, Tong Min Kim, Seung-Hwan Lee, Jae Hyoung Cho, Hyunyong Lee, Hyeon Woo Yim, Kun-Ho Yoon, Hun-Sung Kim
Chỉ có một số ít các nghiên cứu theo dõi lâu dài đã so sánh sự thay đổi chức năng thận theo loại statin được sử dụng ở Hàn Quốc. Nghiên cứu này so sánh tác động lâu dài của cường độ và loại statin lên sự thay đổi của tốc độ lọc cầu thận (GFR). Chúng tôi đã thu thập dữ liệu của những bệnh nhân lần đầu tiên sử dụng statin. Chúng tôi phân tích liệu các loại statin khác nhau có ảnh hưởng đến sự thay đ...... hiện toàn bộ
#statin #tốc độ lọc cầu thận #atorvastatin #fluvastatin #simvastatin #pitavastatin #Hàn Quốc #nghiên cứu theo dõi lâu dài
Chronic hepatitis B virus infection: epidemiology, prevention, and treatment in China
Springer Science and Business Media LLC - Tập 8 - Trang 135-144 - 2014
Rui Yu, Rong Fan, Jinlin Hou
Chronic hepatitis B is a major health problem in China. The universal vaccination program since 1992 has changed the epidemiology of hepatitis B virus infection in China from highly to moderately endemic. The most prevalent hepatitis B virus strains in China are genotypes B and C, whereas those in western provinces are genotypes D and C/D hybrid. Chronic hepatitis B poses a heavy burden to the soc...... hiện toàn bộ
Do not let precision medicine be kidnapped
Springer Science and Business Media LLC - Tập 9 - Trang 512-513 - 2015
Zhiping Yang
Obama’s precision medicine initiative made the medical community boil over after the initiative’s release. Precision medicine has been advocated by the majority of scientists and doctors. However, some experts have questioned this concept. This article does not oppose precision medicine. However, the incentive of vigorously promoting precision medicine at present is a concern.
Clinical characterization and diagnosis of cystic fibrosis through exome sequencing in Chinese infants with Bartter-syndrome-like hypokalemia alkalosis
Springer Science and Business Media LLC - Tập 12 - Trang 550-558 - 2018
Liru Qiu, Fengjie Yang, Yonghua He, Huiqing Yuan, Jianhua Zhou
Cystic fibrosis (CF) is a fatal autosomal-recessive disease caused by mutations in the CF transmembrane conductance regulator (CFTR) gene. CF is characterized by recurrent pulmonary infection with obstructive pulmonary disease. CF is common in the Caucasian population but is rare in the Chinese population. The symptoms of early-stage CF are often untypical and may sometimes manifest as Bartter syn...... hiện toàn bộ
Methodologies for the establishment of an orthotopic transplantation model of ovarian cancer in mice
Springer Science and Business Media LLC - Tập 8 - Trang 101-105 - 2014
Cunjian Yi, Lei Zhang, Fayun Zhang, Li Li, Shengrong Ling, Xiaowen Wang, Xiangqiong Liu, Wei Liang
This study used different methods to establish an animal model of orthotopic transplantation for ovarian cancer to provide an accurate simulation of the mechanism by which tumor occurs and develops in the human body. We implanted 4T1 breast cancer cells stably-transfected with luciferase into BALB/c mice by using three types of orthotopic transplantation methodologies: (1) cultured cells were dire...... hiện toàn bộ
The regulatory sciences for stem cell-based medicinal products
Springer Science and Business Media LLC - Tập 8 - Trang 190-200 - 2014
Bao-Zhu Yuan, Junzhi Wang
Over the past few years, several new achievements have been made from stem cell studies, many of which have moved up from preclinical stages to early, or from early to middle or late, stages thanks to relatively safe profile and preliminary evidence of effectiveness. Moreover, some stem cell-based products have been approved for marketing by different national regulatory authorities. However, many...... hiện toàn bộ
Prognostic analysis of chronic myeloid leukemia in Chinese population in an imatinib era
Springer Science and Business Media LLC - Tập 6 - Trang 204-211 - 2012
Haiyan He, Yang Shen, Yongmei Zhu, Saijuan Chen
We evaluated the outcomes of chronic myeloid leukemia (CML) patients receiving imatinib treatment in chronic (CP), accelerated (AP), and blast crisis (BP) phases. The single-institution treatment experiences of Chinese patients with CML were presented. A total of 275 CML patients (CP, 210; AP, 24; and BP, 41) who received imatinib between February 2001 and April 2008 were enrolled in this study. W...... hiện toàn bộ
Drug-coated balloon-only strategy for percutaneous coronary intervention of de novo left main coronary artery disease: the importance of proper lesion preparation
Springer Science and Business Media LLC - Tập 17 - Trang 75-84 - 2022
Sanna Uskela, Antti Eranti, Jussi M. Kärkkäinen, Tuomas T. Rissanen
This retrospective single-center registry study included all consecutive patients who underwent percutaneous coronary intervention (PCI) for a de novo left main coronary artery lesion using drug coated-balloon (DCB)-only strategy between August 2011 and December 2018. To best of our knowledge, no previous studies of DCB-only strategy of treating de novo left main coronary artery disease, exist. Th...... hiện toàn bộ
Pyogenic liver abscess as initial presentation in locally advanced right colon cancer invading the liver, gallbladder, and duodenum
Springer Science and Business Media LLC - - 2011
Kai Qu, Chang Liu, Aasef Mohamed Ali Mansoor, Bo Wang, Jincai Chen, Yu Lian, Yi Lv
Cohort study of patients with Stevens-Johnson syndrome and toxic epidermal necrolysis in China: evaluation of risk models and new predictor of pulmonary consolidation on computed tomography
Springer Science and Business Media LLC - Tập 15 - Trang 585-593 - 2021
Yanhong Shou, Lu Yang, Yongsheng Yang, Xiaohua Zhu, Feng Li, Bo Yin, Yingyan Zheng, Jinhua Xu
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare but severe diseases. This study aimed to validate the predictive ability of risk models in patients with SJS/TEN and propose possible refinement in China. Patients in the Department of Dermatology of Huashan Hospital from January 2008 to January 2019 were included. Results showed that the severity-of-illness score for TEN...... hiện toàn bộ
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