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Establishment and characterization of SUIT-58 pancreas cancer cell line and its subline S58-SF adapted to serum-free condition derived from metastatic liver tumor
Springer Science and Business Media LLC - Tập 28 Số 4 - Trang 190-198 - 2015
Nobuyasu Takahashi, Fumiyo Aoyama, Jiro Ohuchida, N. Sameshima, Yujiro Asada, Akira Sawaguchi
Establishment and characterization of NCC-PMP2-C1: a novel patient-derived cell line of pseudomyxoma peritonei with signet ring cells
Springer Science and Business Media LLC - - Trang 1-12 - 2023
Rei Noguchi, Yuki Yoshimatsu, Yooksil Sin, Takuya Ono, Ryuto Tsuchiya, Hiroshi Yoshida, Tohru Kiyono, Yutaka Yonemura, Tadashi Kondo
Pseudomyxoma peritonei (PMP) is a rare phenomenon, characterized by accumulation of mucus in the abdominal cavity due to a mucinous neoplasm. Histologically, PMP is divided into three prognostic classes, namely low-grade mucinous carcinoma peritonei (LGMCP), high-grade mucinous carcinoma peritonei (HGMCP), and high-grade mucinous carcinoma peritonei with signet ring cells (HGMCP-S); HGMCP-S exhibi... hiện toàn bộ
Establishment and characterization of a cell-line originated from human mucinous cystadenocarcinoma of the ovary
Springer Science and Business Media LLC - Tập 15 - Trang 171-177 - 2002
Sojiro Sato, Yoichi Kobayashi, Yoshiaki Okuma, Haruhiro Kondo, Yosuke Kanishi, Kaoru Saito, Kazusige Kiguchi
We recently established a cell line (designated 371M) derived from an ovarian mucinous cystadenocarcinoma. The tumor cells were obtained from the ascitic fluid of a 54-year-old Japanese woman while she was undergoing surgery. Adjuvant chemotherapy (combined paclitaxel and carboplatin) was administered, but was ineffective, and she died about 4 months after surgery. The 371M cells continuously prop... hiện toàn bộ
Establishment and characterization of a novel cell line, NCC-TGCT1-C1, derived from a patient with tenosynovial giant cell tumor
Springer Science and Business Media LLC - - 2021
Rei Noguchi, Yuki Yoshimatsu, Takuya Ono, Akane Sei, Kaoru Hirabayashi, Iwao Ozawa, Kazutaka Kikuta, Tadashi Kondo
Identification of LBH and SPP1 involved in hepatic stellate cell activation during liver fibrogenesis
Springer Science and Business Media LLC - Tập 36 - Trang 1054-1067 - 2023
Weiming Dai, Yuecheng Guo, Zhenyang Shen, Junjun Wang, Lungen Lu, Hui Dong, Xiaobo Cai
Liver fibrosis is a pathological response driven by the activation of hepatic stellate cell (HSC). However, the mechanisms of liver fibrosis and HSC activation are complicated and far from being fully understood. We aimed to explore the candidate genes involved in HSC activation during liver fibrogenesis. Five genes (LBH, LGALS3, LOXL1, S100A6 and SPP1) were recurrent in the DEGs derived from the ... hiện toàn bộ
Eight influenza virus cellular manipulations which can boost concurrent SARS-CoV-2 infections to severe outcomes
Springer Science and Business Media LLC -
Kevin Roe
Generation of an induced pluripotent stem cell line from a patient with epileptic encephalopathy caused by the CYFIP2 R87C variant
Springer Science and Business Media LLC - Tập 36 - Trang 2237-2246 - 2023
Isabelle Leticia Zaboroski Silva, Rubens Gomes-Júnior, Evelin Brandão da Silva, Isadora May Vaz, Valderez Ravaglio Jamur, Bruno Solano de Freitas Souza, Patrícia Shigunov
Induced pluripotent stem cells (iPSCs) opened the possibility to use patient cells as a model for several diseases. iPSCs can be reprogrammed from somatic cells collected in a non-invasive way, and then differentiated into any other cell type, while maintaining the donor´s genetic background. CYFIP2 variants were associated with the onset of an early form of epileptic encephalopathy. Studies with ... hiện toàn bộ
Prognostic significance and immune escape implication of tumor-infiltrating neutrophil plasticity in human head and neck squamous cell carcinoma
Springer Science and Business Media LLC - - Trang 1-15 - 2024
Xiaoke Zhu, Yu Heng, Duo Zhang, Di Tang, Jian Zhou, Hanqing Lin, Jingyu Ma, Xuping Ding, Lei Tao, Liming Lu
Tumor-infiltrating neutrophils play a crucial role in the progression of head and neck squamous cell carcinoma (HNSCC). Here, we aimed to statistically quantify the plasticity of HNSCC-infiltrating N2/N1 neutrophils and examine its impacts on survival and immune infiltration landscape. A retrospective study of 80 patients who underwent curative surgical resection for HNSCC between 2014 and 2017 wa... hiện toàn bộ
PRMT5 promotes retinoblastoma development
Springer Science and Business Media LLC - Tập 36 - Trang 329-341 - 2022
Yu Jiang, Guangying Zheng, Xiantao Sun
Epigenetic mechanism, including DNA methylation and histone modifications, contributes to alterations in the expression patterns of genes regulating malignant phenotype of cancer cells. However, the epigenetic modulation of vascular endothelial growth factor-A (VEGFA) in retinoblastoma (RB) has not been clearly established. We aimed to examine the epigenetic regulation of VEGFA by protein arginine... hiện toàn bộ
Review of cancer-associated fibroblasts and their microenvironment in post-chemotherapy recurrence
Springer Science and Business Media LLC - Tập 33 - Trang 938-945 - 2020
Genichiro Ishii, Takahiro Ishii
Cancer tissue comprises not only cancer cells, but also several types of non-cancerous cells, such as cancer-associated fibroblasts. These fibroblasts directly and/or indirectly communicate with the cancer cells and other types of stromal cells, to create a specific tumor microenvironment. Cytotoxic chemotherapy plays a central role in treating cancer; however, tumor re-progression (recurrence) is... hiện toàn bộ
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