Over expression of LDOC1 and PARP1, two pro-apoptotic genes, in a patient with cryptorchidism and DiGeorge anomaly

Michele Salemi1,2, Roberto Castiglione1, Sandro La Vignera1, Rosita A. Condorelli1, Paolo Bosco2, Enzo Vicari1, Aldo E. Calogero1
1Section of Endocrinology, Andrology and Internal Medicine, Department of Internal Medicine and Systemic Diseases, and Master in Andrological and Human Reproduction Sciences, University of Catania, Catania, Italy
2Laboratory of Cytogenetics, IRCS Associazione, Oasi Maria S.S.-Istitute for Research on Mental Retardation and Brain Aging, Troina (ENNA), Italy

Tóm tắt

Từ khóa


Tài liệu tham khảo

Fomin AB, Pastorino AC, Kim CA, Pereira CA, Carneiro-Sampaio M, Abe-Jacob CM. DiGeorge syndrome: a not so rare disease. Clinics (Sao Paulo). 2010;65:865–9. American Psychiatric Association. Diagnostic and statistical manual of mental disorders (DSM-IV), 4th edn. Diagnostic and statistical stages. American Psychiatric Association, Washington, DC 1994. Hutson JM, Balic A, Nation T, Southwell B. Cryptorchidism. Semin Pediatr Surg. 2010;19:215–24. Liu Y, Li X. Molecular basis of cryptorchidism-induced infertility. Sci China Life Sci. 2010;53:1274–83. Gupta S, Aggarwal S, Nguyen T. Increased spontaneous apoptosis in T lymphocytes in DiGeorge anomaly. Clin Exp Imunol. 1998;113:65–71. Nagasaki K, Schem C, von Kaisenberg C, et al. Leucine-zipper protein, LDOC1, inhibits NF-kappaB activation and sensitizes pancreatic cancer cells to apoptosis. Int J Cancer. 2003;105:454–8. Andrabi SA, Kim NS, Yu SW. Poly(ADP-ribose) (PAR) polymer is a death signal. Proc Natl Acad Sci USA. 2006;103:18308–13. Salemi M, Calogero AE, Bosco P, Castiglione R, La Vignera S, Borgione E, Rappazzo G, Vicari E. Expression of SpanX mRNA in testicular germ cell tumours. Hum Cell. 2006;19:87–90. Gareri P, Condorelli D, Belluardo N, Russo E, Loiacono A, Barresi V, Trovato-Salinaro A, Mirone MB, Ferreri Ibbadu G, de Sarro G. Anticonvulsant effects of carbenoxolone in genetically epilepsy prone rats (GEPRs). Neuropharmacology. 2004;47:1205–16. Shprintzen RJ. Velo-cardio-facial syndrome: 30 years of study. Dev Disabil Res Rev. 2008;14:3–10.