Springer Science and Business Media LLC

Công bố khoa học tiêu biểu

* Dữ liệu chỉ mang tính chất tham khảo

Sắp xếp:  
Turning sex inside-out: Peripheral contributions to sexual differentiation of the central nervous system
Springer Science and Business Media LLC - Tập 3 - Trang 1-9 - 2012
Ashlyn Swift-Gallant, Lee Niel, D Ashley Monks
Sexual differentiation of the nervous system occurs via the interplay of genetics, endocrinology and social experience through development. Much of the research into mechanisms of sexual differentiation has been driven by an implicit theoretical framework in which these causal factors act primarily and directly on sexually dimorphic neural populations within the central nervous system. This review...... hiện toàn bộ
Sex differences in metabolic phenotype and hypothalamic inflammation in the 3xTg-AD mouse model of Alzheimer’s disease
Springer Science and Business Media LLC - Tập 14 - Trang 1-12 - 2023
Lisa S. Robison, Olivia J. Gannon, Abigail E. Salinero, Charly Abi-Ghanem, Richard D. Kelly, David A. Riccio, Febronia M. Mansour, Kristen L. Zuloaga
Alzheimer’s disease (AD) is notably associated with cognitive decline resulting from impaired function of hippocampal and cortical areas; however, several other domains and corresponding brain regions are affected. One such brain region is the hypothalamus, shown to atrophy and develop amyloid and tau pathology in AD patients. The hypothalamus controls several functions necessary for survival, inc...... hiện toàn bộ
Sex differences in stress and immune responses during confinement in Antarctica
Springer Science and Business Media LLC - Tập 10 - Trang 1-17 - 2019
C. Strewe, D. Moser, J.-I. Buchheim, H.-C. Gunga, A. Stahn, B. E. Crucian, B. Fiedel, H. Bauer, P. Gössmann-Lang, D. Thieme, E. Kohlberg, A. Choukèr, M. Feuerecker
Antarctica challenges human explorers by its extreme environment. The effects of these unique conditions on the human physiology need to be understood to best mitigate health problems in Antarctic expedition crews. Moreover, Antarctica is an adequate Earth-bound analogue for long-term space missions. To date, its effects on human physiology have been studied mainly in male cohorts though more fema...... hiện toàn bộ
Considering sex and gender in Epidemiology: a challenge beyond terminology. From conceptual analysis to methodological strategies
Springer Science and Business Media LLC - Tập 13 - Trang 1-10 - 2022
Hélène Colineaux, Alexandra Soulier, Benoit Lepage, Michelle Kelly-Irving
Epidemiologists need tools to measure effects of gender, a complex concept originating in the social sciences which is not easily operationalized in the discipline. Our aim is to clarify useful concepts, measures, paths, effects, and analytical strategies to explore mechanisms of health difference between men and women. We reviewed concepts to clarify their definitions and limitations for their tr...... hiện toàn bộ
Sexually dimorphic effects of early life stress in rat pups on urinary bladder detrusor muscle contractility in adulthood
Springer Science and Business Media LLC - Tập 7 - Trang 1-10 - 2016
Ehsan Mohammadi, Dawn K. Prusator, Eleanor Healing, Robert Hurst, Rheal A. Towner, Amy B. Wisniewski, Beverley Greenwood-Van Meerveld
Painful bladder syndrome/interstitial cystitis (PBS/IC) is a chronic disorder that is commonly seen in women who report a history of adversity in early life. Here, we test the hypothesis that early life stress (ELS) induces sexually dimorphic abnormalities in urinary bladder smooth muscle function in adulthood. Male and female rat pups were conditioned on postnatal (PN) days 8–12 with either a “pr...... hiện toàn bộ
Sex differences in cancer mechanisms
Springer Science and Business Media LLC - Tập 11 - Trang 1-29 - 2020
Joshua B. Rubin, Joseph S. Lagas, Lauren Broestl, Jasmin Sponagel, Nathan Rockwell, Gina Rhee, Sarah F. Rosen, Si Chen, Robyn S. Klein, Princess Imoukhuede, Jingqin Luo
We now know that cancer is many different diseases, with great variation even within a single histological subtype. With the current emphasis on developing personalized approaches to cancer treatment, it is astonishing that we have not yet systematically incorporated the biology of sex differences into our paradigms for laboratory and clinical cancer research. While some sex differences in cancer ...... hiện toàn bộ
Sex differences in neuro(auto)immunity and chronic sciatic nerve pain
Springer Science and Business Media LLC - - 2020
Katja Linher‐Melville, Anita Shah, Gurmit Singh
AbstractChronic pain occurs with greater frequency in women, with a parallel sexually dimorphic trend reported in sufferers of many autoimmune diseases. There is a need to continue examining neuro-immune-endocrine crosstalk in the context of sexual dimorphisms in chronic pain. Several phenomena in particular need to be further explored. In patients, autoantibodies ...... hiện toàn bộ
Sex differences in the association of sphingolipids with age in Dutch and South-Asian Surinamese living in Amsterdam, the Netherlands
Springer Science and Business Media LLC - Tập 12 - Trang 1-14 - 2021
Mirthe Muilwijk, Nardie Callender, Susan Goorden, Frédéric M. Vaz, Irene G. M. van Valkengoed
Men have a higher risk for cardiovascular disease (CVD) early in life, while women have a higher risk later in life. The sex-related differences in CVD risk, especially by age, could be related to sphingolipid metabolism. We compared plasma sphingolipid concentrations and its increase by age in men and women. Plasma concentrations of 13 types of sphingolipids were measured by liquid chromatography...... hiện toàn bộ
Sex-related differences in the associations between plasma free fatty acid levels and clinical features in patients with hypertrophic cardiomyopathy
Springer Science and Business Media LLC - Tập 7 - Trang 1-10 - 2016
Chengzhi Yang, Changlin Zhang, Jiansong Yuan, Jingang Cui, Shengwen Liu, Fenghuan Hu, Weixian Yang, Xuanye Bi, Shubin Qiao
Previous studies have indicated that inefficient energy utilization may play a pivotal role in hypertrophic cardiomyopathy (HCM). However, whether plasma free fatty acid (FFA), a main energy substrate of heart, has an effect on HCM remains unclear. Besides, several studies have suggested sex-related differences in HCM features and FFA metabolism. Here, we aimed to explore the association between p...... hiện toàn bộ
Phương pháp thống kê để kiểm tra mối liên hệ của biến thể trên nhiễm sắc thể X: ứng dụng cho các đặc điểm khác nhau theo giới tính của rối loạn lưỡng cực Dịch bởi AI
Springer Science and Business Media LLC - Tập 10 - Trang 1-11 - 2019
William A. Jons, Colin L. Colby, Susan L. McElroy, Mark A. Frye, Joanna M. Biernacka, Stacey J. Winham
Rối loạn lưỡng cực (BD) ảnh hưởng đến cả hai giới, nhưng có sự khác biệt quan trọng về giới tính liên quan đến triệu chứng và các bệnh đi kèm. Ví dụ, chu kỳ nhanh (RC) gặp nhiều hơn ở phụ nữ, trong khi rối loạn sử dụng rượu (AUD) lại phổ biến hơn ở nam giới. Chúng tôi giả thuyết rằng các biến thể trên nhiễm sắc thể X có thể liên quan đến các đặc điểm khác nhau theo giới tính của BD. Một số ít nghi...... hiện toàn bộ
#rối loạn lưỡng cực #nhiễm sắc thể X #biến thể di truyền #phương pháp thống kê #khác biệt giới tính
Tổng số: 453   
  • 1
  • 2
  • 3
  • 4
  • 5
  • 6
  • 10