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Genome-wide identification of the CER1 gene family in apple and response of MdCER1-1 to drought stress
Springer Science and Business Media LLC - - 2023
Cell-type-specific gene expression patterns in the knee cartilage in an osteoarthritis rat model
Springer Science and Business Media LLC - Tập 18 - Trang 79-87 - 2017
Osteoarthritis (OA) is a chronic degenerative disease that leads to joint failure, pain, and disability. Gene regulation is implicated as a driver of the imbalance between the expression of catabolic and anabolic factors that eventually leads to the degeneration of osteoarthritic cartilage. In our model, knee-joint OA was induced in male Wistar rats by intra-articular sodium monoiodoacetate (MIA) ......
A high-throughput SNP array in the amphidiploid species Brassica napus shows diversity in resistance genes
Springer Science and Business Media LLC - Tập 14 - Trang 643-655 - 2014
Single-nucleotide polymorphisms (SNPs)are molecular markers based on nucleotide variation and can be used for genotyping assays across populations and to track genomic inheritance. SNPs offer a comprehensive genotyping alternative to whole-genome sequencing for both agricultural and research purposes including molecular breeding and diagnostics, genome evolution and genetic diversity analyses, gen......
A comparative genomic analysis of ESTs from Ustilago maydis
Springer Science and Business Media LLC - Tập 4 - Trang 207-218 - 2004
A large-scale comparative genomic analysis of unisequence sets obtained from an Ustilago maydis EST collection was performed against publicly available EST and genomic sequence datasets from 21 species. We annotated 70% of the collection based on similarity to known sequences and recognized protein signatures. Distinct grouping of the ESTs, defined by the presence or absence of similar sequences i......
Probing early wheat grain development via transcriptomic and proteomic approaches
Springer Science and Business Media LLC - - 2019
To understand the molecular changes taking place during the early grain development in common wheat, we profiled transcriptome and proteome of two cultivars, “P271” and “Chinese Spring” (CS) with large and small grains, respectively. More than 85,000 genes and 7500 proteins were identified to express during early grain development in two wheat cultivars. We observed enrichment in the number of gen......
Differential pulmonary transcriptomic profiles in murine lungs infected with low and highly virulent influenza H3N2 viruses reveal dysregulation of TREM1 signaling, cytokines, and chemokines
Springer Science and Business Media LLC - Tập 12 - Trang 105-117 - 2011
Investigating the relationships between critical influenza viral mutations contributing to increased virulence and host expression factors will shed light on the process of severe pathogenesis from the systems biology perspective. We previously generated a mouse-adapted, highly virulent influenza (HVI) virus through serial lung-to-lung passaging of a human influenza H3N2 virus strain that causes l......
The structural organisation of the gene encoding class II starch synthase of wheat and barley and the evolution of the genes encoding starch synthases in plants
Springer Science and Business Media LLC - Tập 3 - Trang 76-85 - 2003
Wheat and barley contain at least four classes of starch synthases in the endosperm, granule bound starch synthase I (GBSSI) and starch synthases I, II and III (SSI, SSII, SSIII). In this work, SSII in barley is shown to be associated with the starch granule by using antibodies. A cDNA from barley encoding SSII and the genes for SSII from barley and Aegilops tauschii (A. tauschii, the D genome do......
Unraveling the potential of senescence-related genes in guiding clinical therapy of lung adenocarcinoma patients
Springer Science and Business Media LLC - Tập 23 - Trang 1-17 - 2023
Lung adenocarcinoma (LUAD) is the most common histological type of lung cancer. In recent years, cell senescence emerges as a potential therapeutic target of cancer therapy. However, the role of cell senescence in LUAD has not been comprehensively unveiled. One single cell RNA sequencing (scRNA-seq) dataset (GSE149655) and two bulk RNA-seq datasets (TCGA and GSE31210) of LUAD were included. Seurat......
Transcriptome profiling of short-term response to chilling stress in tolerant and sensitive Oryza sativa ssp. Japonica seedlings
Springer Science and Business Media LLC - Tập 18 - Trang 627-644 - 2018
Low temperature is a major factor limiting rice growth and yield, and seedling is one of the developmental stages at which sensitivity to chilling stress is higher. Tolerance to chilling is a complex quantitative trait, so one of the most effective approaches to identify genes and pathways involved is to compare the stress-induced expression changes between tolerant and sensitive genotypes. Phenot......
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