Cell-type-specific gene expression patterns in the knee cartilage in an osteoarthritis rat modelSpringer Science and Business Media LLC - Tập 18 - Trang 79-87 - 2017
Michal Korostynski, Natalia Malek, Marcin Piechota, Katarzyna Starowicz
Osteoarthritis (OA) is a chronic degenerative disease that leads to joint
failure, pain, and disability. Gene regulation is implicated as a driver of the
imbalance between the expression of catabolic and anabolic factors that
eventually leads to the degeneration of osteoarthritic cartilage. In our model,
knee-joint OA was induced in male Wistar rats by intra-articular sodium
monoiodoacetate (MIA) ... hiện toàn bộ
MPZL1 suppresses the cancer stem-like properties of lung cancer through β-catenin/TCF4 signalingSpringer Science and Business Media LLC - Tập 23 - Trang 1-10 - 2023
Qiao Ge, Chao Zhou, Chao Zang, Chao Li, Haining Hong, Kangwu Wang, Liwei Chen, Haonan Zhu, Ansheng Wang
This study was designed to explore the influence of myelin protein zero-like
protein 1 (MPZL1) on the stem-like properties of cancer cells and the underlying
mechanism in lung adenocarcinoma. Real-time quantitative polymerase chain
reaction (RT-qPCR) was utilized to evaluate mRNA expression level. CCK8, wound
healing, and transwell assays were applied to assess cell proliferation,
migration, and i... hiện toàn bộ
Monitoring expression profiles of Arabidopsis genes during cold acclimation and deacclimation using DNA microarraysSpringer Science and Business Media LLC - Tập 6 - Trang 212-234 - 2006
Youko Oono, Motoaki Seki, Masakazu Satou, Kei Iida, Kenji Akiyama, Tetsuya Sakurai, Miki Fujita, Kazuko Yamaguchi-Shinozaki, Kazuo Shinozaki
A comparative analysis of gene expression profiles during cold acclimation and
deacclimation is necessary to elucidate the molecular mechanisms of cold stress
responses in higher plants. We analyzed gene expression profiles in the process
of cold acclimation and deacclimation (recovery from cold stress) using two
microarray systems, the 7K RAFL cDNA microarray and the Agilent 22K
oligonucleotide a... hiện toàn bộ
A high-throughput SNP array in the amphidiploid species Brassica napus shows diversity in resistance genesSpringer Science and Business Media LLC - Tập 14 - Trang 643-655 - 2014
Jessica Dalton-Morgan, Alice Hayward, Salman Alamery, Reece Tollenaere, Annaliese S. Mason, Emma Campbell, Dhwani Patel, Michał T. Lorenc, Bin Yi, Yan Long, Jinling Meng, Rosy Raman, Harsh Raman, Cindy Lawley, David Edwards, Jacqueline Batley
Single-nucleotide polymorphisms (SNPs)are molecular markers based on nucleotide
variation and can be used for genotyping assays across populations and to track
genomic inheritance. SNPs offer a comprehensive genotyping alternative to
whole-genome sequencing for both agricultural and research purposes including
molecular breeding and diagnostics, genome evolution and genetic diversity
analyses, gen... hiện toàn bộ
Spinach-based RNA mimicking GFP in plant cellsSpringer Science and Business Media LLC - Tập 22 - Trang 423-428 - 2022
Zhiming Yu, Yue Wang, Fengling Mei, Haiting Yan, Zhenhui Jin, Pengcheng Zhang, Xian Zhang, Mahmut Tör, Stephen Jackson, Nongnong Shi, Yiguo Hong
Spinach RNA-mimicking GFP (S-RMG) has been successfully used to monitor cellular
RNAs including microRNAs in bacterium, yeast, and human cells. However, S-RMG
has not been established in plants. In this study, we found that like bacterial,
yeast, and human cellular tRNAs, plant tRNAs such as tRNALys can protect and/or
stabilize the Spinach RNA aptamer interaction with the fluorophore DFHBI
enablin... hiện toàn bộ
Starch content differences between two sweet potato accessions are associated with specific changes in gene expressionSpringer Science and Business Media LLC - Tập 18 - Trang 613-625 - 2018
Songtao Yang, Xiaojing Liu, Shuai Qiao, Wenfang Tan, Ming Li, Junyan Feng, Cong Zhang, Xiang Kang, Tianbao Huang, Youlin Zhu, Lan Yang, Dong Wang
Sweet potato (Ipomoea batatas (L.) Lam.) is one of the most important root crops
in the world. Initial formation and development of storage roots (SRs) are key
factors affecting its yields. In order to study the molecular mechanism and
regulatory networks of the SRs development process, we have analyzed root
transcriptomes between the high and low starch content sweet potato accessions
at three di... hiện toàn bộ